Repro Ex III PART TRES (mostly testes) Flashcards

(33 cards)

1
Q

What is the tumor marker for the yolk sac tumor of infancy produce?

A

AFP-Alpha FetoProtein

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2
Q

What is the homologous tumor of the yolk sac tumor?

A

Endodermal Sinus Tumor in the ovary

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3
Q

Which is more severe: an embryonal carcinoma or Seminoma?

A

Embryonal carcinoma is more aggressive and lethal then a Seminoma

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4
Q

What 8 tissues can be found in a testicular teratoma? DO I find teeth like the female germ cells tumors?

A

1.neural 2.skeletal 3.cartilage 4.thyroid 5.respiratory 6.epithelium 7.Squamous epi 8.GI tract..no teeth :(

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5
Q

How does age of the Pt relate to malignancy in a Testicular Teratoma?

A

The older and more mature the teratoma the more malignant.

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6
Q

What is the female equivalent to the Testicular Teratoma?

A

The Dermoid Cyst/ovarian teratoma

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7
Q

What are the two hormone producing tumors of the testies? What do they secrete?

A
  1. Leydig Cell Tumor/Interstitial Cell Tumor (androgens, estrogens, or both) 2.Sertoli Cell Tumor (mostly estrogen, some androgen)
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8
Q

What is the tumor that is a highly malignant testicular tumor, which represents germ cell extraembryonic differentiation to the components of the placenta, namely, cyto and syncytiotrophoblast?

A

A Choricocarcinoma!

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9
Q

Which tumor has no testicular enlargement and is detected as a small, painless nodule?

A

a choriocarcinoma

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10
Q

Which tumor am I? Microscopically, the trophoblastic tissues are found in the areas of hemorrhage.

A

a choriocarcinoma

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11
Q

What is a marker for a choriocarcinoma?

A

hCG

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12
Q

What cancer represents the most common urinary tract neoplasm?

A

Cancer of the Urinary Bladder

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13
Q

What is the EGYPTIAN parasite that has been linked to causing bladder cancer?

A

Sc-hist-o-soma Hae-mat-o-bium

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14
Q

Which prostate tumor markers are made by the prostate itself? Which marker is made elsewhere?

A

PSA and PAP are made by the prostate….Alkaline Phosphatase made by osteoblasts in the bone

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15
Q

What are the two markers that would indicate in an old man that prostate cancer has metastasized to the bone?

A

PAP and Alkaline phosphatase

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16
Q

What does BPH stand for?

A

Benign Prostatic Hyperplasia

17
Q

What type of cancer is prostate cancer?

A

Adenocarcinoma (the prostate is a gland!)

18
Q

Who is most likely to get BPH???It is most frequent in Western Europe and the ___ and least common in the ______. The prevalence is higher among U.S. _____ than whites and the disease peaks at about ___ years.
75% of men over 80 years of age have some degree of BPH. It is rare to see this disease in men younger than _____.

A

U.S…..Orient…blacks…70 years…40 years

19
Q

What is the pathogenesis of BPH?

A

Testosterone plays a crucial role, castration stopped development of BPH

20
Q

DOES BPH PROGRESS TO CANCER?

A

no (at least the almighty NIH says so)

21
Q

What does TURP stand for?

A

TransUrethral Resection of the Prostate

22
Q

Which ethnic group has the highest risk for BPH? Prostate Cancer?

A

Blacks & Blacks

23
Q

The prostate contains about 30-50 individual compound tubuloalveolar ____, each gland having its own duct that delivers the secretory product to the ________.

A

glands…prostatic urethra

24
Q

The prostate is about the size of a _______, and secretes an _______ fluid and constitutes 13-33% of semen.

A

chestnut…alkaline

25
The prostate is a single _______-shaped gland that lies inferior to the urinary bladder and surrounds the upper portion of the urethra.
doughnut
26
What type of epithelium lines the prostate gland?
simple-->pseudo stratified columnar epithelium
27
What are the lumens of the prostate gland usually surrounded by? (composed of calcified glycoproteins)
CORPORA AMYLACEA
28
What organism causes acute prostatitis? What host cell is going to show up first?
E.Coli....PMNs
29
What are the 3 hallmark cells of chronic bacterial prostatitis?
Lymphocytes, Plasma Cells, Macrophages
30
What 2 organisms are most likely to cause granulates prostatitis?
1.Mycobacterium tuberculosis and 2. Histoplasma capsulatum
31
What is a good GLEASON score? What is a bad score? What are the majority of prostate cancers?
Majority pattern (1-5) + minority pattern (1-5)....BEST score 2....WORST score 10...majority of prostate cancers are 4-7
32
Both malignant and ______ prostatic cells express a specific antigen called Prostate Specific Antigen (PSA).
NORMAL!
33
The PSA levels in the serum usually correlate with the cancer _______.
volume