F1- Practice Flashcards

(46 cards)

1
Q

Alpha
Fast growing

A

Herpes simplex virus type 1
Herpes simplex virus type 2
Varicella-zoster virus

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2
Q

Beta
Slow growing

A

Cytomegalovirus
Human herpesvirus 6
Human herpesvirus 7

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3
Q

Gamma

A

Epstein-Barr virus
Kaposi sarcoma-associated herpesvirus

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4
Q

Neurons

A

Herpes simplex virus type 1
Herpes simplex virus type 2
Varicella-zoster virus

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5
Q

Glands, kidneys

A

Cytomegalovirus

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6
Q

Lymphoid tissue

A

Human herpesvirus 6
Human herpesvirus 7
Epstein-Barr virus
Kaposi sarcoma-associated herpesvirus

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7
Q

Short, cytolytic

A

Herpes simplex virus type 1
Herpes simplex virus type 2
Varicella-zoster virus

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8
Q

Long, cytomegalic

A

Cytomegalovirus

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9
Q

Long, lymphoproliferative

A

Human herpesvirus 6
Human herpesvirus 7

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10
Q

Variable, lymphoproliferative

A

Epstein-Barr virus
Kaposi sarcoma-associated herpesvirus

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11
Q

• Causes GENITAL HSV infections;
latency in the sacral ganglia

• Reactivation occurs most frequently below the waist

• Affect young adults; sexual contact (typical transmission)

A

HSV-2 INFECTIONS IN HUMANS

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12
Q

Typical transmission of HSV-2 INFECTIONS IN HUMANS

A

• Affect young adults; sexual contact

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13
Q

Neonatal infections (skin, eye, mouth; encephalitis; disseminated)

(5) causes???

A

ToRCHeS:

Toxoplasmosis
Rubella
Cytomegalovirus
Herpes (or HIV)
Syphilis

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14
Q

Primary infection:
• Severe, painful genital herpes (lasts 3 weeks), with fever, malaise, dysuria, & inguinal lymphadenopathy
• Neonatal infections (skin, eye, mouth; encephalitis; disseminated)

A

HSV-2 INFECTIONS IN HUMANS

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15
Q

Painful urination, burning sensation, uncomfortable walking irritated by clothing

• Mostly transmitted when no lesions or symptoms are apparent

• Semen may contain the virus

A

HSV-2 INFECTIONS IN HUMANS: Genital Herpes

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16
Q
  • mild (primary) acute, highly contagious disease of children

A generalized vesicular eruptions of the skin & mucous membranes, itchy exanthematous rash, blisters dry & form scabs in 4-5 days, 300-400 lesions (severe in adults & immunocompromised individuals)

A

Varicella (chickenpox)

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17
Q

reactivation of varicella virus present in latent form in
neurons in sensory ganglia

A

Herpes zoster (shingles)

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18
Q

sporadic, incapacitating disease of the elderly & immunocompromised

• CXS: Severe pain, numbness, & itchy vesicular rash along sensory nerves (a single sensory ganglion) of head or trunk; postherpetic neuralgia

A

Herpes zoster (shingles)

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19
Q

headache,
fever,
malaise,
fatigue,
sore throat,
enlarged lymph nodes & spleen, some signs of hepatitis;

A

EPSTEIN-BARR Virus (EBV)

Intectious Mononucleosis

20
Q

Lesions: small, pink, pearl-like lesions molluscum) or wart-like tumors on the face, arms, back, and buttocks

rarely on palms, soles, or mucous membranes

1-5 mm in diameter, has a dimple center or umbilicated;

A

MOLLUSCUM CONTAGIOSUM VIRUS

21
Q

(henderson-Paterson bodies)

A

MOLLUSCUM CONTAGIOSUM VIRUS

22
Q

progressive multifocal leukoencephalopathy (a CNS (demyelinating) complication in immunosuppressed individuals

latent - kidneys, B cells, monocyte-lineage

A

JC virus

Polyomaviridae

23
Q

nephropathy in transplant recipients;

latent - kidneys

A

BK Virus

Polyomaviridae

24
Q

Merkel cell skin carcinomas, skin tumors of neuroendocrine origin

A

Merkel cell virus

Polyomaviridae

25
a primate polyomavirus, infects humans detected in brain tumors, mesotheliomas, bone marrows, & lymphomas
SV40
26
contaminated early lots of live and killed poliovirus vaccines that had been grown in monkey cells unknowingly infected with SV40 (between 1955-1963. Fecal-oral route in humans probable. Low prevalence in humans.
SV40
27
**Most common viral infection of the reproductive tract,***660 million people worldwide Accepted as the cause of anogenital cancers, ***99% cervical cancer,*** 80% anal cancers;
PAPILLOMAVIRIDAE - HUMAN PAPILLOMAVIRUS (HPV)
28
PARVOVIRIDAE - Human parvoviruses Human parvovirus B19 GENUS?
Erythroparvovirus genus
29
PARVOVIRIDAE - Human parvoviruses • Human bocavirus GENUS?
Bocaparvovirus genus
30
Transmitted through ***exposure to infected blood & bodily fluids*** (semen, vaginal secretions); It survives for prolonged periods outside the body
Hepatitis B Viral Infections
31
Most infections are acquired through ***perinatal transmission at birth,*** through horizontal transmission to/between young children, through sexual concact, through injecting drug use; 15-29 years old; throughout the year incidence.
Hepatitis B Viral Infections
32
Hepatitis B Most infections are acquired through…
perinatal transmission at birth
33
HbsAg - Negative Anti-HBs - Positive Anti-HBc - Positive
Indicates previous HBV infection and immunity to hepatitis B.
34
Indicates previous HBV infection and immunity to hepatitis B.
HbsAg - Negative Anti-HBs - Positive Anti-HBc - Positive
35
Detectable in ***high levels in serum during acute or chronic infections.*** Infectious except if transiently positive within 30 days after a dose of HepB vaccine.
HBsAg Hepatitis B surface antigen.
36
Detectable in ***new acute infection.*** ***Indicates viral replication, *** circulates as soluble antigen in serum. Associated with higher HBV DNA levels, thus increase infectiousness;
HBeAg Hepatitis B e-antigen.
37
Indicates ***past infection*** ***with immunity to HBV, *** presence of passive antibody from HBIG, or immune response from HBV vaccine.
Anti-HBs Antibody to HBsAg.
38
Indicates early convalescence.
Anti-HBe Antibody to HBeAg.
39
Indicates ***infection with HBV at some undefined time in the past.*** A marker of past HBV infection (remains + indefinitely)
Anti-HBc Antibody to HBcAg.
40
Indicates ***new acute infection with HBV;*** positive for within 6-9 months after infection or liver flare. Followup.
IgM anti-HBc IgM class antibody to HBcAg.
41
Class I → DS, Enveloped, Icosahedral/Complex
Herpesviridae, Poxviridae
42
Class I → DS, Naked, icosahedral
Papillomaviridae, Polyomaviridae (Papovaviridae), Adenoviridae
43
Class Il → SS, Naked, Icosahedral
Parvoviridae
44
Class VIII → DS, Enveloped, Icosahedral
Hepadnaviridae
45
Standard List of rash-causing childhood diseases: First: measles Second: scarlet fever Third: rubella Fourth: Duke's disease (no longer in use) Fifth:______ Sixth:_______
erythema infectiosum roseola
46
Fifth disease Slapped cheek syndrome
erythema infectiosum PARVOVIRIDAE