F2- Practice

Question 1

SARS-CoV 1&2:
cellular receptors - (2)

MERS-CoV: (1)

Answer 1

angiotensin-converting
enzyme 2 (ACE2) &
transmembrane
protease, serine 2 (TMPRSS2)

dipeptidyl peptidase 4 (DPP4)

Question 2

Coronaviridae
 Dx:

Answer 2

RT-PCR (GOLDEN STANDARD)

CRISPR-based assays

Question 3

Most common cause of adult GASTROENTERITIS

Answer 3

Noroviruses (Norwalk viruses)

Question 4

T or F

Norovirus

Naked virus:
Acid stable (survive in the GIT), resistant to heat (60° C),
pH 3, detergent, even chlorine levels of drinking water

Answer 4

True

Naked sila

Question 5

very small unit;

28 to 30 nm naked icosahedral
capsid,

+ssRNA,

infectious
genome-linked protein (VPg)

Answer 5

Picornaviridae

Question 6

(foot-and-mouth disease virus)

Answer 6

Aphthovirus

Question 7

Enteroviruses

Answer 7

Rhino
Echo
Entero
Cox
HAV

Question 8

Hand-foot-and-mouth disease: lesions on hands, feet, mouth, tongue;

Types 5, 10, 16

Answer 8

Coxsackie A viruses [Types 1-24]

Question 9

German measles, or three-day measles

Answer 9

Rubella- Togaviridae

Question 10

DENV

• detects viral antigen during early phase
  (1-5 days of illness)

Answer 10

Dengue NS 1 RDT

Question 11

High-impact high-threat disease, with risk of international spread, represents a potential threat to global health security

Answer 11

YELLOW FEVER

Question 12

A positive ____and____confirms HCV infection but cannot distinguish between acute and chronic infection.

If negative, recheck in 4 weeks.

Answer 12

HCV antibody and positive HCV RNA

Question 13

Parenteral transmission

Answer 13

BCD

Question 14

Fecal oral HEPATITIS

Answer 14

AE

Question 15

Hepatitis CHRONIC DISEASE

Answer 15

Often BCD

Question 16

Hepatitis NEVER CHRONIC DISEASE

Answer 16

AE

Question 17

Naked HEPATITIS

Answer 17

AE

Question 18

The only DNA Hepatitis

Answer 18

HBV