F3: Fecalysis (Part 2: Malabsorption-Intestinal Hypermobility) Flashcards
- Impaired absorption of fats, carbohydrates and proteins
- Results in: Creatorrhea and Steatorrhea
Malabsorption
MALABSORPTION
Increased meat fibers
Creatorrhea
MALABSORPTION
- Increased fats in stool (>6 g/day)
- Pancreatic disorders
- Malabsorption
- Absence of bile salts
Steatorrhea
Identify if Maldigestion or Malabsorption
- Deficiency of pancreatic enzymes (Pancreatitis, Cystic Fibrosis, Pancreatic Cancer)
- Decreased bile acid formation
Maldigestion
Identify if Maldigestion or Malabsorption
- Damaged intestinal mucosa (Celiac disease, Tropical Sprue)
- Lymphatic obstruction (Lymphoma, Whipple disease)
Malabsorption
T or F
Villi of patient with celiac disease absorb fewer nutrients due to inflammation (presents shorter villi)
T
Villi helps in the reabsorption of the nutrients; present in the small intestine
- Fecal fat
- Useful in diagnosing pancreatic insufficiency and small-bowel disorders that cause malabsorption
- Absence of bile salts that assist pancreatic lipase in the breakdown and subsequent reabsorption of dietary fat ( produces an increase in stool fat (steatorrhea) that exceeds 6 g per day)
- Present in those with either maldigestion or malabsorption conditions and can be distinguished by the D-xylose test
Steatorrhea
STEATORRHEA
Steatorrhea helps indicates
a. Pancreatic overload
b. Small-bowel disorders
c. both
d. NOTA
b. Small-bowel disorders
For a to be correct, it should be:
a. Pancreatic insufficiency
STEATORRHEA
These assist pancreatic lipase in the breakdown and subsequent reabsorption of dietary fat (primarily triglycerides)
Bile salts
STEATORRHEA
T or F
In STEATORRHEA, there is absence of bile salts which decreases digestion and reabosprotion
T
STEATORRHEA
T or F
Absence of bile salts = increase in stool fat exceeding 4g per day
F (Absence of bile salts = increase in stool fat exceeding 6g per day)
STEATORRHEA
Maldigestion or malabsoprtion conditions leading to steatorrhea can be distinguised by using what test?
D XYLOSE TEST
STEATORRHEA
- To distinguish pancreatic insufficiency (maldigestion) from intestinal malabsorption
- Absorbed without the aid of pancreatic enzymes
- Give 25g of D xylose orally
- Specimens: Blood, Urine
D xylose test
D XYLOSE TEST
Amount of D xylose taken orally by patient?
25g of D xylose
D XYLOSE TEST
What (2) specimens can be used for D xylose test
- Blood
- Urine
D XYLOSE TEST
T or F
For maldigestion or pancreatic insufficiency, d xylose value is normal
T
D XYLOSE TEST
Normal D xylose test indicates
a. Xylose is still absorbed by body even if there is pancreatic insufficiency or maldigestion
b. Xylose is unabsorbed by body because there is pancreatic insufficiency or maldigestion
c. Xylose is unabsorbed by body because there is malabsorpotion
d. Xylose is still absorbed by body because there is malabsorpotion
a. Xylose is still absorbed by body even if there is pancreatic insufficiency or maldigestion
D XYLOSE TEST
Decrease D xylose test indicates
a. Xylose is still absorbed by body even if there is pancreatic insufficiency or maldigestion
b. Xylose is unabsorbed by body because there is pancreatic insufficiency or maldigestion
c. Xylose is unabsorbed by body because there is malabsorption
d. Xylose is still absorbed by body because there is malabsorption
c. Xylose is unabsorbed by body because there is malabsorpotion
D XYLOSE TEST
Condition where there is decreased d xylose (less than 3 g)
Malabsorption syndrome
D XYLOSE TEST
Identify if Blood or Urine specimen is used
after 2 hrs should present xylose
Blood
D XYLOSE TEST
Identify if Blood or Urine specimen is used
5 hr-urine should present xylose
Urine specimen
D XYLOSE TEST
- Condition where there is decreased d-xylose
- Causes of this condition: Bacterial overgrowth, Intestinal resection, Celiac disease, Tropical sprue, Lymphoma
Malabsorption syndrome
D XYLOSE TEST
Why is xylose still absorbed in maldigestionn or pancreatic insufficiency?
a. Xylose is a disaccharide hence absorbed,
b. Xylose is a monosaccharide hence absorbed
c. Xylose is a monosaccharide, neither digested or absorbed
c. Xylose is a disaccharide, neither digested or absorbed
b. Xylose is a monosaccharide hence absorbed, indicating normal intestinal absorption
Monosaccharide: may be absorbed as is, should not need any aid
D XYLOSE TEST
Sugars that are absorbed as is, does not need any aid
ex. Xylose
Monosaccharides
