Final Exam GI Physiology: Small Intestine Flashcards Preview

RUSVM Physiology II > Final Exam GI Physiology: Small Intestine > Flashcards

Flashcards in Final Exam GI Physiology: Small Intestine Deck (23):
1

The small intestine produces three types of secretions. Name them.

Exocrine, Paracrine, and Endocrine

2

What do goblet cells secrete?

Mucin

3

What do crypt cells secrete?

Cl- followed by Na+, K+, and H20
Also secretes guanylin

4

Secretagogue neurotransmitters of the small intestine include...?

VIP and ACh
Guanylin

5

Why is guanylin unique?

It is an exocrine secretagogue which results in increased secretion

6

What does the toxin that many pathogenic enteric bacteria have developed do?

Stimulate the guanylin receptor which results in secretory diarrhea leading to death via hypovolemia, hypotension and shock

7

What does histamine do at the small intestine?

Increases secretory activity and is vasodilatory

8

What do prostaglandins do at the small intestine?

Increases secretory activity and is vasodilatory

9

What promotes the secretion of GIP?

glucose, fatty acids and monoacylglycerols

10

What does GIP do?

It's an incretin and promotes the release of insulin

11

What does CCK do?

Promotes contraction of the gallbladder
Promotes pancreatic acinar secretion
Inhibits gastric motility
Inhibits HCl secretion

12

What stimuli promote the secretion of CCK?

Fatty acids, monoacylglycerols and AAs

13

What is known as "nature's antacid"?

Secretin

14

What stimulates the release of secretin?

Luminal pH less than 3.5

15

What does secretin stimulate the release of?

Bile and pancreatic ductular cells

16

What does secretin inhibit?

Gastrin secretion
Gastric motility
Gastric emptying

17

T or F: Since secretin and CCK act to inhibit gastric emptying, both are important elements of the enterogastric reflex.

True

18

Where is gastrin produced?

By the G-cells in the mucosa

19

What does gastrin stimulate?

Gastric secretion
Closure of pyloric sphincter
Delays gastric emptying

20

What is GLP-1?

Glucagon-like peptide 1

21

What does GLP-1 do?

It is a potent incretin (along with GIP)

22

Where is GLP-1 secreted?

By mucosal cells of the ileum

23

What stimulates the release of GLP-1?

Food breakdown products