Practice Test FEBRUARY 2007: Test 2 Flashcards Preview

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Flashcards in Practice Test FEBRUARY 2007: Test 2 Deck (39):
1

If plasma osmolality is 300 mOsm, what is the best estimate of filtrate osmolality in the urinary space?

300 mOsm

2

All reabsorptive and secretory processes in the nephron are ultimately attributable to the activity of _________?

Basolateral Na+K+ ATPase

3

Each of the following undergoes a decrease in filtrate concentration as filtrate flows through the proximal tubule EXCEPT:
a. protein
b. glucose
c. HCO3-
d. urea
e. phosphate

d. Urea does not undergo a decrease in concentration through the proximal tubule

-Protein, glucose, HCO3-, and phosphate all decrease in concentration through the proximal tubule

4

Plasma [creatinine] is 0.7 mg/dL. The excretion rate of creatinine is 8 mg/min. The GFR is 10 dL/min. At what rate is creatinine secreted?

1 mg/min

5

Why is iohexol clearance preferred over creatinine clearance as a kidney function test?

Because urine is not collected in the iohexol test

6

What is a common clinical finding in an animal with renal amyloidosis?

Pronounced proteinuria

7

Each is synthesized in the kidney EXCEPT:
a. urea
b. calcitriol
c. erythropoeitin
d. renin
e. glucose

a. Urea is not made in the kidney.

-Calcitriol, Erythropoeitin, Renin, and Glucose CAN all be synthesized in the kidney

8

An animal has just experienced a decrease in normal blood pressure. What is the renal autoregulatory response to this decrease?

DILATION of AA. and CONSTRICTION of EA

9

Renal plasma flow in a normal kidney is 200 ml/min. What is the best estimate for plasma flow leaving the efferent arterioles and entering peritubular capillaries?

135 ml/min

10

Over what period of time is the entire plasma volume of an animal filtered?

30 minutes

11

What is found ONLY in the proximal tubule?

Na+Phosphate Symport

12

What best characterizes the urine of an animal with diabetes insipidus?

High flow and (+) free water clearance

13

The nephron is net secretory for K+ where?

DCT and CCD only

14

The nephron is net reabsorptive where?

PCT, LOH, DCT and CCD

15

If plasma [Na+] in the renal artery is 140 mOsm, what is the best estimate of of plasma [Na+] in the renal vein?

140 mOsm

16

Where is [Cl-] the greatest?

Filtrate entering the 2nd half of the PCT

17

ADH exerts a KNOWN effect on each of the following EXCEPT:
a. CCD
b. PCT
c. DCT
d. aLOH

b. PCT is not effected by ADH

18

Aldosterone promotes each of the following at target cells of the kidney EXCEPT:
a. Active transport of K+ into the filtrate
b. Increased number of Na+ ports in the luminal membrane
c. Increased activity of Na+K+ATPase
d. Increased number of K+ ports in the luminal membrane

a. Active transport of K+ into the filtrate is NOT promoted by aldosterone

19

Catecholamines exert KNOWN effects on each of the following EXCEPT:
a. Afferent Arteriole
b. aLOH
c. Efferent Arteriole
d. PCT

b. aLOH is not effected by catecholamines

20

T or F: PCOP in plasma entering peritubular capillaries is greater than PCOP in plasma leaving peritubular capillaries

T

21

T or F: Creatinine concentration in the renal vein is greater than creatinine concentration in the renal artery

F

22

T or F: Urea concentration in aLOH filtrate is greater than urea concentration at the end of the nephron

F

23

T or F: Na+ concentration entering in filtrate is greater than Na+ concentration entering DCT

T

24

T or F: Urine osmolality of an animal on a high protein diet is greater than urine osmolality of an animal on a low protein diet

T

25

T or F: The excretion ratio of creatinine is greater than the excretion ration of glucose

T

26

T or F: The osmolality of plasma entering the vasa recta is greater than the osmolality of plasma leaving the vasa recta

F

27

T or F: The "single effect" of a nephron refers to the separation of solute and water at the aLOH

T

28

T or F: An animal the consumes too much fresh water should exhibit a (+) free water clearance, a USG less than 1.008, and low plasma [ADH]

T

29

T or F: Low plasma [urea] is a sign of kidney disease

F

30

T or F: The PCT is the major site of phosphate secretion in the nephron

F

31

T or F: Calcium oxalate crystalluria is a common finding in an animal that has consumed large amounts of ethylene glycol

T

32

T or F: Elevated plasma [urea] is a more common finding than elevated plasma [creatinine] in an animal with a ruptured bladder

T

33

T or F: Filtered albumin is endocytosed and exocytosed by the PCT

F

34

T or F: Aldosterone antagonists are diuretics

T

35

T or F: Urea is a uremic toxin

F

36

T or F: Approximately 90% of plasma osmolality is attributed to the 4 most abundant electrolytes in plasma

T

37

T or F: Transcellular and paracellular reabsorption of K+ occur in the PCT

F

38

T or F: Transcellular and paracellular reabsorption of Na+ occurs in the aLOH

T

39

T or F: Catecholamines promote the secretion of Renin and ANP

F