Fungi

Question 1

Unlike bacteria
Unlike plant
Cell wall

Answer 1

Eukaryotic
Lack property of photosynthesis
Chitin

Question 2

Fungal disease usually…..

Answer 2

Chronic

Question 3

Classification depending on morphology

Answer 3

1 yeast unicellular produced by budding
2 mold multicellular filamentous
3 dimorphic fungi mostly pathogenic

Question 4

Branching cylindrical tubules

Answer 4

Hyphe

Question 5

Mass of interwined hyphe called

Answer 5

Mycelium

Question 6

Hyphe divided into….. And other ….

Answer 6

Septate
Non septate

Question 7

Parasitic form seen in

Answer 7

Tissu, exudates, or enriched media at 37
Seen as yeast

Question 8

In nature or if grown at 25 exis as

Answer 8

Mold (mycelia)

Question 9

Why it’s difficult to make antimycotic therapy

Answer 9

Because drugs that inhabit the synthesis of DNA and RNA or protein in fungal may have the same effect on human cells

Question 10

Fungal cell wall.
Rigid cell wall of…

Answer 10

Chitin

Question 11

Fungal membrane contain……. Where as mammalian cells contain……
This difference is the basic for…

Answer 11

Ergosterol
Cholesterol
Fungal sensitivity to intimycotic agent

Question 12

Asexual spores formed by….

Answer 12

Modification of hyphe

Question 13

Pityriasis versicolore or……. Caused by…….

Answer 13

Tinea versicolor
Malassezia furfur mould septate hyphae

Question 14

Disease of pityriasis versicolor

Infected area recognized by..

Answer 14

Dépigmentation of infected skin may be accompanied by itching
By discoloration

Question 15

Diagnosis of
Pityriasis versicolor
Tinea versicolor

Answer 15

Microscopic examination koh
Treated skin scraping

Question 16

The lesion of pityriasis versicolor appear fluorescence yellow orange under…….. Lesion found in……

Answer 16

Wood light
Trunk and arms

Question 17

Tenia Nigra….

Answer 17

Brown to black macular lesion usually on the hands and feet and the causative agent fungus found in soil and environment

Question 18

Piedra is infection of……. Caused by…….. And……….

Answer 18

Scalp hair
Piedraia hortae and Trichosporon Beigelii

Question 19

p.hortae is a dark pigmented……. cause….., Small brown black modules are formed on……..
Dark coloured thick…….

Answer 19

Mould
Black piedra
Hair surface
Hyphae

Question 20

Trichosporon Beigelii is not…… Infect………. Causing…….
White nodules are formed having………

Answer 20

Dark coloured
Course of hair (axillary, facial, genital)
White piedra
No pigmented hyphae

Question 21

Diagnosis of peidra

Answer 21

Microscopic examination koh
p.hortea show dark coloured branching thick septete hyphae+Ascospores sexal
Trichosporon Beigelii show soft white or pale brown hyphae+arthrospores

Question 22

Another name of cutaneous mycosis

Answer 22

Dermatophytosis
Ring worm
Tinea

Question 23

Ring worm affect……

Answer 23

Keratinized tissue of nails and hair and skin

Question 24

…. Infect skin and hair and nails
….infect skin and hair not nails
….infect skin and nails

Answer 24

Trichophyton Rubrum
Microsporum
M.canis

Question 25

Tenea corporis

Answer 25

Ring worm occur any where on the body

Question 26

Tinea pedis

Answer 26

Athletes foot Toe webs and sole of feets

Question 27

Tinea unguium

Answer 27

Onchomycosis Infections of nails

Question 28

Tinea manuum

Answer 28

Infections of hands

Question 29

Tinea capitis

Answer 29

Affect scalp of children transmitted by comb in school going children

Question 30

Tinea cruris

Answer 30

Jock itch Infections of groin, perineum, perianal

Question 31

Tinea barbae

Answer 31

Ring worm of bearded area on face

Question 32

Skin ring worm common in ......

Answer 32

Moist sweaty skin folds Obisity increase susceptibility to infection beneath breast and tight clothes help infection in groin

Question 33

Maceration and moisture help setting infections between......

Answer 33

Toes (athletes foot)

Question 34

Lab diagnosis of tinea

Answer 34

Skin scraped from advancing edge (septete hyphae) Dermatophytes fluoresce seen under u.v light (wood lamp)

Question 35

Treatment of ring worm Tinea

Answer 35

Topical therapy Tolneftate,Naftifne,clotrimazole.miconazole Oral therapy griseofulvin or ketoconazole or allylamine (nails bed infections)

Question 36

Subcutaneous mycosis

Answer 36

Introduced by injury through the skin Involved subcutaneous tissue،lymphatic tissue, and nearby tissue Rarely spread to distan organ

Question 37

Etiology of sporotrichosis

Answer 37

Sporothrix schenckii Dimorphic fungi Cigar shaped yeast in tissue

Question 38

Sporothrix schenckii is....... found in soil in decaying organic matter. Acquired by....

Answer 38

Ubiquitous saprophytes Traumatic inoculation through skin of Gardeners, farmers

Question 39

Pathology of sporothrix schenckii

Answer 39

Pyogenic and granulomatous inflammation

Question 40

Skin lesions of sporothrix schenckii begin as...... ....... Is most often involved ...... Later...........

Answer 40

Painless papule Hand Papule Ulcerate, draining lymph channels thickened or firm nodules

Question 41

Diagnosis of Sporothrix schenckii

Answer 41

Specimens Direct microscopic examination Culture sda,bhia

Question 42

In sporothrix schenckii Koh preparation usually........ Due to.....

Answer 42

Negative Small number of fungi

Question 43

Asteroid bodies in the lesion of......

Answer 43

Sporothrix schenckii Is central fungus cell surrounded by refractile esinophilic halo called Splendor hoeppli phenomenon due to complex deposition around the organisms

Question 44

Culture of sporothrix schenckii

Answer 44

Septate hyphae Very thin carry flower like cluster of small conidia

Question 45

Treatment of sporothrix schenckii

Answer 45

Itraconazole Sever amphotericin B

Question 46

Chromoblastomycosis?

Answer 46

Chronic warty mycosis of the skin and subcutaneous tissue cused by Phialophora and cladosporium genera which are pigment producing filamentous fungi

Question 47

Chromoblastomycosis occur in.....or..... Appear as..... that develop after several years into......... Extension is.... And...... And doesn't involve.....

Answer 47

Foot or legs Papule Flat scaly or warty like structure under the feet like tips of Cauliflower Slow Painless Lymphatic vessels

Question 48

Lab diagnosis of chromoblastomycosis depending on...

Answer 48

Culture and isolation

Question 49

In chromoblastomycosis Diagnosis Organisms are called........... Fungi because they grow as......... The pigment accumulates in the mycelia cell wall in culture and in tissue......

Answer 49

Dematiaceous Black colonies Sclerotic bodies

Question 50

Treatment of chromoblastomycosis

Answer 50

Surgery and antifungal therapy Itraconazole , amphotericin B and fluorocytosine

Question 51

Mycetoma is........ It characterised by......... It's typically affect the........... Predominantly occur in......

Answer 51

Chronic granulomatous disease of the skin and subcutaneous tissue which sometimes involve muscle bone and neighboring organ Tumefaction, abscess formation, and fistulae Lower extremities Farm workers

Question 52

Mycetoma swelling is ..... And contain...... ...... Containing small granules.... Is discharge through..... Which opens on the skin surface

Answer 52

Nodular Sinuses Mucopus Colonies Sinuses

Question 53

Diagnosis of mycetoma

Answer 53

Specimens exudates from sinuses And biopsy from granules Culture

Question 54

Treatment of mycetoma

Answer 54

Surgical excision Ketoconazole 1,3 years Actinomycetes mycetoma respond to antibiotics and sulphonamide