General Neurophysiology iBook Flashcards Preview

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Flashcards in General Neurophysiology iBook Deck (16):
1

in the case of acidosis the firing rate of chemoreceptors will ___ and in alkalosis the rate will __

increase, decrease

2

kidney has 2 types of intercalated cells that use carbonic anhydrase reaction

Type A secretes ___
Type B secretes___

A = H+
B = HCO3-

3

acidosis activates which type of intercalated cells?

type A bc secretes H+ into tubule
-bicarb absorbed

4

CO2 can enter the CSF then what

it gets converted to H+ and HCO3- so changes in CO2 will alter the pH of the CSF just as they do the blood
-

5

if one is chronically high on CO2, CSF will be too ____
-cells making CSF will make and add ___ to CSF while pumping the ____ ion made to ____

acidic
HCO3-
H+ ion made to the blood

6

what enzyme does the choroid plexus have

carbonic anhydrase

7

what happens to the pH of the CSF if a patient is suffering from metabolic acidosis?

nothing because H+ ions cannot cross BBB

8

CSF pathway

from ventricle--> through foramens of Magendie and Luschka ---> to subarachnoid space

9

what is another way CSF is taken up by arachnoid villi

pinocytosis by mesothelailal cells of arachnoid villi
-remainder diffuses directly into cerebral blood vessels

10

what is an external hydrocephalus or communicating hydrocephalus?

decreased absorptive capacity of the arachnoid villi

11

what is internal hydrocephalus or noncommunicating

blockage of either foramen or somewhere else in the ventricular system

12

physiological importance of little mixing/crossing of blood in circle of willis

reduced blood flow in any one of the contributing vessels is not corrected by admixture from the other vessels po

13

post ganglionic symp fibers: innervation of Cereb vasc

cell bodies in superior cervical ganglia: NPY and norep
-alpha adrenergic receptors cause vasoconstriction

14

as intracranial presure increases, blood flow is ___ due to what

reduced due to compression of the BV

15

if there is an increase in intracranial pressure it ___ blood flow to the brain which triggers what

reduce
triggers the increase in systemic MAP even if the systemic BP is normal/high

16

what is one sign of an increase in intracranial pressure

increase in systemic blood pressure