General Neurophysiology iBook Flashcards Preview

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Flashcards in General Neurophysiology iBook Deck (16)
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1
Q

in the case of acidosis the firing rate of chemoreceptors will ___ and in alkalosis the rate will __

A

increase, decrease

2
Q

kidney has 2 types of intercalated cells that use carbonic anhydrase reaction

Type A secretes ___
Type B secretes___

A
A = H+
B = HCO3-
3
Q

acidosis activates which type of intercalated cells?

A

type A bc secretes H+ into tubule

-bicarb absorbed

4
Q

CO2 can enter the CSF then what

A
5
Q

if one is chronically high on CO2, CSF will be too ____

-cells making CSF will make and add ___ to CSF while pumping the ____ ion made to ____

A

acidic
HCO3-
H+ ion made to the blood

6
Q

what enzyme does the choroid plexus have

A

carbonic anhydrase

7
Q

what happens to the pH of the CSF if a patient is suffering from metabolic acidosis?

A

nothing because H+ ions cannot cross BBB

8
Q

CSF pathway

A

from ventricle–> through foramens of Magendie and Luschka —> to subarachnoid space

9
Q

what is another way CSF is taken up by arachnoid villi

A

pinocytosis by mesothelailal cells of arachnoid villi

-remainder diffuses directly into cerebral blood vessels

10
Q

what is an external hydrocephalus or communicating hydrocephalus?

A

decreased absorptive capacity of the arachnoid villi

11
Q

what is internal hydrocephalus or noncommunicating

A

blockage of either foramen or somewhere else in the ventricular system

12
Q

physiological importance of little mixing/crossing of blood in circle of willis

A

reduced blood flow in any one of the contributing vessels is not corrected by admixture from the other vessels po

13
Q

post ganglionic symp fibers: innervation of Cereb vasc

A

cell bodies in superior cervical ganglia: NPY and norep

-alpha adrenergic receptors cause vasoconstriction

14
Q

as intracranial presure increases, blood flow is ___ due to what

A

reduced due to compression of the BV

15
Q

if there is an increase in intracranial pressure it ___ blood flow to the brain which triggers what

A

reduce

triggers the increase in systemic MAP even if the systemic BP is normal/high

16
Q

what is one sign of an increase in intracranial pressure

A

increase in systemic blood pressure