GI - 5 Liver Disease pt 4 Flashcards Preview

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Flashcards in GI - 5 Liver Disease pt 4 Deck (21)
1

AST>ALT usually by 2x or more. AST rarely >300, not nearly as high as viral hepatitis in:

Alcoholic liver disease

2

#1 treatment for alcoholic liver disease is

abstinence

3

3 causes of cirrhosis. which is most common?

Chronic Heb B and C, alcohol (most common)

4

What causes cirrhosis in Autoimmune Hep?

High AMA - irritatoin and swelling blocking bile flow - primary biliary cirrhosis

5

Big symptom of cirrhosis is:

loss of libido

6

First check which 2 places for jaundice?

Conjunctiva and sclera of eyes

7

Treatment of cirrhosis

Treat the underlying disorder
Healthy diet, no alcohol
Check sonogram and AFP q 6 mos***

8

What makes encephalopathy worse? (2)

Ace inhibitors & narcotics

9

Azotemia without shock or significant proteinuria
Failure of renal function to improve after fluids
Oliguria (not urinating b/c of low blood flow to kidneys), hyponatremia, low urinary sodium
Increased renal vasoconstriction, kidneys nl
Often terminal
Kidneys are normal though

Hepatorenal syndrome

10

__ is most measurable toxin but not solely responsible for Hepatic encephalopathy

Ammonia

11

Ammonia is the most measurable toxin, but NOT solely responsible for:

Hepatic encephalopathy

12

Flapping of the hands is a sign of

Hepatic encephalopathy

13

Why should you restrict protein in hepatic encephalopathy?

protein breakdown creates ammonia

14

Treatment for hepatic encephalopathy. how does it work?

Lactulose - makes ammonia into ammonium so it can pass thru GI tract

15

Arise from parenchymal cells
80% associated with cirrhosis
Men>women
Chronic hepatitis B and C infections, Etoh, hemochromatosis, NASH (non alcoholic steato? hepatitis)

Hepatocellular Carcinoma

16

cancer of the actual ducts

Cholangio carcinoma

17

Lab, diagnosis, and staging of Hepatocellular Carcinoma: (3)

Serum alpha-fetoprotein levels
MRI
Staging: PET Scan

18

4 causes of Nonalcoholic Fatty Liver Disease

Obesity, Diabetes, High Triglycerides, Meds (various)

19

Obese + alcoholic =

Steatosis

20

Signs and symptoms of Steatosis
What test diagnoses it?

Steatosis is mainly asymptomatic
Dx: Ultrasound

21

Which one has high LFT’s? Steatohepatitis or Steatosis?

Steatohepatitis