GI - 8 Antibiotic Associated Diarrhea and C. Diff Flashcards Preview

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Flashcards in GI - 8 Antibiotic Associated Diarrhea and C. Diff Deck (15)
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1
Q

Is antibiotic-associated diarrhea common?

A

Hells yes

2
Q

What resolves antibiotic associated diarrhea?

A

Discontinuation of antibiotic

3
Q

What’s the most common cause of antibiotic-associated diarrhea?

A

changes in colonic bacterial fermentation of carbohydrates (C diff causes fewer cases)

4
Q

What’s the cause of Antibiotic-associated colitis?

A

C diff

5
Q

How does Antibiotic-associated colitis happen?

A

Antibiotics knock out good flora as well as bad flora. Then a hospital patient/staff passes C. Diff to them and they get this.

6
Q

Drug to treat antibiotic associated colitis

A

Clindamycin

7
Q

2 examples of fluoroquinolones:

A

Ciprofloxicin, levofloxicin

8
Q

Mild-mod greenish, foul smelling watery diarrhea
Lower abdominal cramps when going to the bathroom
Normal or mild left lower quadrant tenderness

A

C diff diarrhea

9
Q

The key 2 symptoms of C Diff colitis are:

A

Watery diarrhea

with mucous and lots of blood

10
Q

What’s a test to diagnose C diff? How does it work?

A

PCR - tests for toxin B (one of A&B toxins made by C diff)

11
Q

Yellow adherent plaques over colonic mucosa is a sign of:

A

Pseudomembranous colitis

12
Q

What imaging test is done for patients with severe symptomatology when rapid diagnosis needed?

A

Sigmoidoscopy

13
Q

Drug for treating Pseudomembranous colitis

A

Metronidazole

14
Q

What’s the difference between Antibiotic-associated colitis and antibiotic associated pseudomembranous colitis?

A

Pseudomembranous colitis is a very severse case of antibiotic-associated colitis. It has yellow adherent plaques as well

15
Q

Drug for relapses of antibiotc pseudomembranous colitis

A

**Most relapses respond promptly to a 2nd course of metronidazole therapy.