Flashcards in GI III Deck (63)
Describe the epithelium of small intestines
mainly absorptive columnar cells with well-developed brush borders
What type of lymphocytes are located in the mucosa of the small intestines?
intraepithelial lymphocytes (T cells)
Loose connective tissue that extends into the villi
Lamina propria of the small intestines
What are lacteals?
well endowed with blood and lymphatic vessels (within the lamina propria)
Where are goblet cells found in the small intestines?
their numbers increase as the ileum is approached
What is another name of intestinal glands found in lamina propria of the small intestines?
crypts of Lieberkuhn
What type of epithelium does crypts of Lieberkuhn have?
What are the three different cell types of the intestinal glands?
1) paneth cells
2) enteroendocrine cells
3) stem cells
What's the function of paneth cells?
secrete lysozyme, defensins, and tumor necrosis factor alpha
Paneth cells extend into which structure?
Where are the stem cell niche located?
at the base of the gland (different than the stomach)
Where does enteroendocrine cells secrete their products, toward the lumen or tissues?
Toward the tissues NOT the lumen
Which segment is the shortest of small intestines?
Which layer are the glands located in the duodenum?
Which gland is a signature feature of the duodenum?
What's the function of Brunner's glands?
secrete mucus and human epidermal growth factor
Which part of the duodenum are Brunner's glands most developed?
Which has a thicker wall, jejunum or ileum?
Which is more richly vascularized, jejunum or ileum?
jejunum (redder than ileun)
Which part of the small intestines are Peyer's patches located?
Which part of the small intestines will you find M cells?
Peyer's patches of the ileum and lymphoid tissues of gut as well
Instead of plicae circulares, what does the large intestines have?
plicae semilunares - permanent folds of mucosa and submucosa
Does the large intestines have villi?
Does the large intestines have brush border?
Yes, but it's poorly developed
True or False. Goblet cells are more numerous in the small intestine than the large intestine
False, it's the other way around
Does the crypt density increase or decrease in large intestine? What about goblet cell density?
Why is paucity of lymphatic channels significant?
an intramucosal carcinoma has little or no potential to metastasize
In which direction does the lymphatics of large intestine extend, radially or longitudinally?
Which smooth muscle layer does not completely surround the large intestine?