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Flashcards in GI III Deck (63)
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1

Describe the epithelium of small intestines

mainly absorptive columnar cells with well-developed brush borders

2

What type of lymphocytes are located in the mucosa of the small intestines?

intraepithelial lymphocytes (T cells)

3

Loose connective tissue that extends into the villi

Lamina propria of the small intestines

4

What are lacteals?

well endowed with blood and lymphatic vessels (within the lamina propria)

5

Where are goblet cells found in the small intestines?

their numbers increase as the ileum is approached

6

What is another name of intestinal glands found in lamina propria of the small intestines?

crypts of Lieberkuhn

7

What type of epithelium does crypts of Lieberkuhn have?

simple columnar

8

What are the three different cell types of the intestinal glands?

1) paneth cells
2) enteroendocrine cells
3) stem cells

9

What's the function of paneth cells?

secrete lysozyme, defensins, and tumor necrosis factor alpha

10

Paneth cells extend into which structure?

right colon

11

Where are the stem cell niche located?

at the base of the gland (different than the stomach)

12

Where does enteroendocrine cells secrete their products, toward the lumen or tissues?

Toward the tissues NOT the lumen

13

Which segment is the shortest of small intestines?

duodenum

14

Which layer are the glands located in the duodenum?

submucosa

15

Which gland is a signature feature of the duodenum?

Brunner's glands

16

What's the function of Brunner's glands?

secrete mucus and human epidermal growth factor

17

Which part of the duodenum are Brunner's glands most developed?

proximal

18

Which has a thicker wall, jejunum or ileum?

jejunum

19

Which is more richly vascularized, jejunum or ileum?

jejunum (redder than ileun)

20

Which part of the small intestines are Peyer's patches located?

ileum

21

Which part of the small intestines will you find M cells?

Peyer's patches of the ileum and lymphoid tissues of gut as well

22

Instead of plicae circulares, what does the large intestines have?

plicae semilunares - permanent folds of mucosa and submucosa

23

Does the large intestines have villi?

NO

24

Does the large intestines have brush border?

Yes, but it's poorly developed

25

True or False. Goblet cells are more numerous in the small intestine than the large intestine

False, it's the other way around

26

Does the crypt density increase or decrease in large intestine? What about goblet cell density?

Both increase

27

Why is paucity of lymphatic channels significant?

an intramucosal carcinoma has little or no potential to metastasize

28

In which direction does the lymphatics of large intestine extend, radially or longitudinally?

radially

29

Which smooth muscle layer does not completely surround the large intestine?

outer longitudinal

30

What is teniae coli?

three longitudinal bands of smooth muscle found in the muscularis externa