GIT

Question 1

ulcer associated with burns and trauma

Answer 1

CuRLing ulcers

Question 2

ulcers associated with increased ICP due to TBI

Answer 2

CuSHings ulcer

Question 3

MC type of esophageal atresia

Answer 3

Type C, distal tracheoesophageal fistula with proximal esophageal atresia

Question 4

MC form of congenital intestinal atresia

Answer 4

imperforate anus - failure of cloacal membrane involution

Question 5

posterolateral defect of diaphragmatic hernia, left sided

Answer 5

Bochdalek - most common

Question 6

anteromedial defect of diaphragmatic hernia

Answer 6

Morgagni

Question 7

MC congenital anomaly of the GI tract

Answer 7

Meckel diverticulum

Question 8

2 association of Pyloric Stenosis

Answer 8

Turner syndrome, Trisomy 18
Erythromycin/Azithromycin exposure in 1st 2 weeks of life

Question 9

mutation in Hirschsprung disease

Answer 9

RET mutations

Question 10

MC esophageal obstruction

Answer 10

Nutcracker esophagus
high amplitude contractions of the distal esophagus

Question 11

false diverticulum above UES
Cricopharyngeus dysfunction
regurgitation, halitosis

Answer 11

Pharyngoesophageal/ Zenker

Question 12

Plummer Vinson syndrome TRIAD

Answer 12

UE webs
IDA
Glossitis, Cheilosis

webs: semi-circumferential ledge-like mucosal protrusions

Question 13

TRIAD of Achalasia (aganglionic esophagus)

Answer 13

Incomplete LES relaxation
Increase LES tone
Esophageal aperistalsis

Question 14

longitudinal mucosal tear near GEJ
severe retching or vomiting
hematemesis
antipersitaltic contractile wave

Answer 14

Mallory Weiss tear

Question 15

MCC of esophageal varices

Answer 15

Liver cirrhosis

Question 16

hallmark of barrett esophagus

Answer 16

Goblet cells

Question 17

MC Esophageal carcinoma

Answer 17

Squamous Cell Carcinoma
site: middle thrid

Question 18

Precursor lesion of Squamous cell carcinoma

Answer 18

Squamous dysplasia

Question 19

which has an increased acid secretion in PUD

Answer 19

Duodenal Ulcer

Question 20

disease characterized by GIANT CEREBRRIFORM enlargement of rugal folds due to epithelial hyperplasia without inflammation

Answer 20

Hypertrophic Gastropathies

Question 21

MC gastric polyp

Answer 21

Inflammatory/hyperplastic polyp
assoc with H. pylori infection

Question 22

MC malignancy of GI

Answer 22

Adenocarcinoma

Question 23

MC site of extranodal lymphomas

Answer 23

Stomach

Question 24

MC mesenchymal tumor of the abdomen

Answer 24

GI stromal tumor

Question 25

Mutation in WNT signaling Bulky exophytic masses Ulcerative infiltrative masses Glandular structures lined by dysplastic intestinal-type epithelial cellsq

Answer 25

Intestinal Gastic Ca

Question 26

loss of function mutation of CDH1 Linitis plastica Dyscohesive cells Signet-ring cells

Answer 26

Diffuse infiltrative Gastric Ca

Question 27

Thickened stiff wall with flattened rugae (leather bottle appearance)

Answer 27

Linitis plastica

Question 28

virulence factor of H.pylori

Answer 28

CagA

Question 29

MC GI Lymphoma

Answer 29

Extranodal Marginal Zone B cell Lymphoma

Question 30

Only malignancy that can be cured by antibiotics

Answer 30

MALT lymphoma H. pylori eradication

Question 31

Carney TRIAD

Answer 31

GIST Paraganglioma pulmonary chondroma

Question 32

Cytogenic origin of GIST

Answer 32

interstitial cells of Cajal

Question 33

MC site of ishemic bowel disease

Answer 33

Colon

Question 34

painful, bloody, small-volume diarrhea

Answer 34

Exudative diarrhea seen in Amebic dysentery

Question 35

most feared long-term complication of UC and CD

Answer 35

Colitis associated neoplasia

Question 36

Hallmark of Chrons

Answer 36

Noncaseating granulomas

Question 37

AD, site: SI multiple GI hamartomatous polyp and mucocutaneous hyperpigmentation `

Answer 37

Peutz Jeghers polyp

Question 38

factors of malignancy risk for colorectal adenoma

Answer 38

Size - >/4cm architecture - villous degree of dysplasia - high-grade

Question 39

Amsterdam criteria of Verified Lynch Syndrome

Answer 39

3 members (1 should be 1st degree relative) 2 generations 1 diagnosed under 50 y/o

Question 40

MC malignancy of GI tract

Answer 40

Colorectal adenoCa

Question 41

gatekeeper of colonic mucosa

Answer 41

APC

Question 42

Histologic criterion of AP

Answer 42

PMN in muscularis propria

Question 43

IHC for GIST

Answer 43

CD117

Question 44

Mucinous tumors of the appendix spread to the peritoneum -- causing build-up of semisolid mucin in the abdomen

Answer 44

pseudomyxoma peritonei

Question 45

neuroendocrine tumors found in which part of the body tend to be multiple and aggressive

Answer 45

midgut - jejunum and ileum

Question 46

MC site foe neuroendocrine tumors

Answer 46

SI