Liver, Pancreas

Question 1

acidophilic apoptotic bodies

Answer 1

Councilman bodies

Question 2

Test of Hepatocyte integrity

Answer 2

ALT AST LDH

Question 3

Test for Hepatocyte synthetic function

Answer 3

Albumin
PT aPTT
Ammonia

Question 4

Test of Biliary excretory function

Answer 4

Bilirubin
ALP
gamma - glutamyl transpeptidase

Question 5

MCC of Portal hypertension

Answer 5

Cirrhosis 85%

Question 6

Characteristic of Ascites

Answer 6

Serous, <3g/dL protein (mostly albumin)
Serum:ascitic fluid albumin gradient >/1.1g/dL

Question 7

Hepatitis that can cause severe hepatitis in pregnant

Answer 7

HEV

Question 8

Hepatitis that is more associated with chronic liver disease

Answer 8

HCV

Question 9

Hallmark of chronic viral hepatitis

Answer 9

Portal inflammation with fibrosis

Question 10

Hepatitis C specific findings

Answer 10

CaLaBaSa

Lymphoid follicles
Bile duct injury
Steatosis

Question 11

Specific findings in Hepatitis B

Answer 11

Ground Glass hepatocytes

Question 12

inflammatory cells (lymphocyte and plasma cells) within cytoplasm of hepatocytes

Answer 12

Emperipolesis
seen in AI Hepatitis

Question 13

hepatocellular pattern seen in Drug induced hepatitis

Answer 13

centrizonal necrosis

Question 14

Diagnosis criteria of NASH

Answer 14

Steatosis
Lobular inflammation
Ballooned hepatocytes

Question 15

MCC of chronic liver disease in US

Answer 15

Non-alcoholic Fatty Liver disease (NAFLD)
Assoc with Metabolic syndrome

Question 16

TRIAD of Hemochormatosis

Answer 16

Micronodular cirrhosis
DM
Skin pigmentation

Excessive Iron absorption and deposition into liver and pancreas

Question 17

AD, impaired Cu excretion into bile and incorporation to Ceruloplasmin
ATP7B mutation Ch13
Movement disorder
Kayser-Fleischer rings

Answer 17

Wilson Disease
inc tissue Cu, Dec serum ceruloplasmin, inc urinary Cu excretion

Question 18

MC diagnosed inherited hepatic disorder in infants and children

Answer 18

A1 antitrypsin deficiency

Question 19

AR, MRP2 mutation (impaired transport of non-bile salt organic anions at canalicular membrane)
black liver discoloration

Answer 19

Dubin-Johnson

Question 20

AR
Impaired STORAGE of conjugated bilirubin in hepatocytes

Answer 20

Rotor syndrome

Question 21

Charcots TRIAD

Answer 21

Fever
Jaundice
RUQ pain

Question 22

Cholestatis and paucity of bile ducts

Answer 22

Alagille syndrome

Question 23

Severe UGT1A1 deficiency

Answer 23

Criggler-Naijar Type 1
this involved in conjugation of bilirubin

Question 24

Treatment for Extrahepatic biliary atresia

Answer 24

Kasai procedure

Question 25

Associated conditions Primary Biliary Cholangitis

Answer 25

Sjogren syndrome Hashimoto thyroditis Scelroderma female, + AMA histo: Florid duct lesion, elongated cirrhotic nodules nodular regenerative hyperplasia

Question 26

Radiology seen in Primary Sclerosing Cholangitis

Answer 26

Strictures and beading of large bile ducts assoc. IBD + ANCA onion skin strictures

Question 27

Sequelae of PBC

Answer 27

Increase risk of HCC

Question 28

Sequalae of PSC

Answer 28

inc risk of cholangicarcinoma

Question 29

MCC of small portal vein obstruction

Answer 29

Schistomiasis

Question 30

Sinusoidal dilation secondary to impaired efflux of hepatic bloody

Answer 30

Peliosis hepatis

Question 31

liver enlargement, pain and ascites secondary to thrombosis

Answer 31

Budd-Chiari Syndrome

Question 32

MC benign tumor

Answer 32

Cavernous Hemangioma

Question 33

MC liver tumor of early childhood

Answer 33

Hepatoblastoma

Question 34

MC primary malignant tumor

Answer 34

HCC

Question 35

2nd MC Primary malignant tumor

Answer 35

Cholangiocarcinoma

Question 36

Nodules/tumor: obese young women, taking OCP and anabolic steroid angiography: Hypovascular

Answer 36

Hepatocellular adenoma assoc with: OPCa and anabolic steroid Obese, metabolic syndrome

Question 37

Adult women central stellate scar angiography: Hypervascular wtih dense capillary blush

Answer 37

Focal nodular hyperplasia (vascular lesion) liver scan: Normal to inc uptake

Question 38

MC Congenital anomaly of the Gallbladder

Answer 38

folded fundus "Phrygian cap"

Question 39

mucosal cholesterol-laden macrophages

Answer 39

Cholesterolosis radiolucent seen in Cholesterol stone

Question 40

MC biliary tract disease

Answer 40

Cholelithiasis RF: forty, female, fat

Question 41

Calculous Mononuclear cells in GB Rokitansky-Aschoff sinuses

Answer 41

Chronic Cholecystitis notable forms: Porcelain GB - calcification Hyalinazing - fibrosing Xanthogranulomatous cholecystitis Hydrops

Question 42

MC pancreatic anomaly

Answer 42

Pancreatic divisum failure of fusion of fetal pancreatic ducts

Question 43

congenital anomaly cause by mutation of PDX1 mutation

Answer 43

Agenesis of pancreas