Glaucoma Drugs Flashcards Preview

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Flashcards in Glaucoma Drugs Deck (18)
1

Name the alpha agonists for glaucoma

epinephrine (alpha1) and brimonidine (alpha2)

2

Mechanism of alpha agonists for glaucoma

decrease aqueous humor synthesis (via vasoconstriction is alpha1 effect)

3

Side effects of epinephrine for glaucoma

mydriasis (alpha1); do NOT use in closed-angle glaucoma

4

Side effects of brimonidine for glaucoma

blurry vision, ocular hyperemia, foreign body sensation, ocular allergic reactions, ocular pruritis

5

Name the beta blockers for glaucoma

timolol
betaxolol
carteolol

6

Mechanism of beta blockers for glaucoma

decrease aqueous humor synthesis

7

Side effects of beta blockers for glaucoma

no pupillary or vision changes

8

Name the diuretic used for glaucoma

acetazolamide

9

Mechanism of acetazolamide for glaucoma

decrease aqueous humor synthesis via inhibition of carbonic anhydrase

10

Side effect of acetazolamide for glaucoma

no pupillary or vision changes

11

Name the direct cholinomimetics for glaucoma

pilocarpine
carbachol

12

Name the indirect cholinomimetics for glaucoma

physostigmine
echothiophate

13

Mechanism of direct/indirect cholinomimetics for glaucoma

increase outflow of aqueous humor via contraction of ciliary muscle and opening of trabecular meshwork

14

Side effects of direct/indirect cholinomimetics for glaucoma

miosis (contraction of pupillary sphincter muscle)
cyclospasm (contraction of ciliary muscle)

15

Special note about pilocarpine for glaucoma

use in emergencies
very effective at opening meshwork into canal of Schlemm

16

Name the prostaglandin for glaucoma

latanoprost (PGF2alpha)

17

Mechanism of latanoprost for glaucoma

increase outflow of aqueous humor

18

Side effect of latanoprost for glaucoma

darkens color of iris (browning)