Glaucoma Drugs Flashcards Preview

Pharmacology > Glaucoma Drugs > Flashcards

Flashcards in Glaucoma Drugs Deck (16):
1

Alpha-agonists used for glaucoma?

Epinephrine, brimonidine

2

B-blockers used for glaucoma?

Timolol, betaxolol, carteolol

3

Diuretic used for glaucoma?

Acetazolamide

4

Cholinemimetics used for glaucoma?

Direct--pilocarpine, carbachol; indirect--physostigmine, echothiophate

5

Prostaglandin used for glaucoma?

Latanoprost (PGF2a)

6

MOA of epinphrine?

Decreases aqueous humor synthesis via vasoconstriction

7

MOA of brimonidine?

Decrease aqueous humor synthesis

8

MOA of B-blockers?

Decrease aqueous humor secretion

9

MOA of diuretics?

Decrease aqueous humor secretion via lowering HCO3- (by inhibiting carbonic anhydrase)

10

MOA of cholinomimetics?

Increase outflow of aqueous humor via contraction of ciliary muscle and opening of trabecular meshwork

11

What is used in emergencies?

Pilocarpine--very effective at opening meshwork into canal of Schlemm

12

MOA of latanoprost?

Increase outflow of aqueous humor

13

What drug is contraindicated in closed angle glaucoma?

Epinephrine

14

Which drug may darken the color the iris (browning)?

Latanoprost

15

Drugs that decrease aqueous humor SYNTHESIS?

1) Alpha agonist
2) B blockers
3) Acetazolamide

16

Drugs that increase OUTFLOW?

1) Cholinomimetics
2) Latanoprost