Glia 1 2..0

Question 2

Four types of glia?

Answer 2

Astrocyte, microglia, oligodendroglia, schwann cell

Question 3

Roles of oligodendrocytes and schwann cells?

Answer 3

Myelinate the neurones

Question 4

Location of oligodendrocytes?

Answer 4

Brain, SC (CNS)

Question 5

Location of schwann cells?

Answer 5

PNS

Question 6

2 examples of neural cells?

Answer 6

Neurons or glia

Question 7

Two subtypes of glia?

Answer 7

Macroglia and microglia

Question 8

Four types of macroglia?

Answer 8

Astrocytes, radial glia, oligodendroglia, schwann cells

Question 9

Role of myelinating glia?

Answer 9

Encase the axon with a myelin sheath

Question 10

Role of myelin sheath?

Answer 10

Insulates axons and speeds up the rate of nerve conduction of AP along axons

Question 11

Roles of radial glia?

Answer 11

Provide scaffolding during nervous system development, pathways for migrating cells
Produce matrix and adhesion proteins

Question 12

Why are radial glia no longer needed into adulthood?

Answer 12

No more neuronal migration is occurring

Question 13

Radial glia role in adults?

Answer 13

Persits in cerebellum (Bergmann glia) and retina (Muller cells)

Question 14

Role of cerebral spinal fluid?

Answer 14

brain health, allows movement of various molecules

Question 15

Where are ependymal cells found?

Answer 15

Lining walls of fluid filled ventricles in the brain

Question 16

Functional component of ependymal cells?

Answer 16

Beating cilia that allows movement of cerebral spinal fluid over the brain and SC

Question 17

Embryonic origin of neurons, astrocytes and oligodendrocytes?

Answer 17

Neural tube

Question 18

Embryonic origin of schwann cells?

Answer 18

Neural crese

Question 19

Origin of microglia?

Answer 19

Derived from macrophages (blood)

Question 20

Embryonic origin of microglia?

Answer 20

Blood cells that develop in the placental yolk region

Question 21

Which two cell types can neuroepithelial stem cells develop into?

Answer 21

Neurons or glial-restricted precursors

Question 22

Which cell types can glial-restricted precursors differentiate into?

Answer 22

Astrocyte precursor cells or O2A progenitors

Question 23

Which cell types can O2A progenitors differentiate into?

Answer 23

Oligodendrocytes or type 2 astrocytes

Question 24

Which cell type does astrocyte precursor cell differentiate into?

Answer 24

Type 1 astrocytes

Question 25

Which type of astrocyte is mainly found in the brain?

Answer 25

Type 1

Question 26

Which cell type that was made in culture has not been identified in the brain?

Answer 26

Type 2 astrocytes

Question 27

Role of projections coming out of astrocytes?

Answer 27

Make contact with other cells in the environment

Question 28

Role of projections coming out of oligodendrocytes?

Answer 28

Wrap around axons to make the myelin sheath

Question 29

Where, embryonically, do the majority of microglia come from?

Answer 29

Placental yolk

Question 30

What happens to microglia in development after being generated by macrophages?

Answer 30

They migrate to the brain

Question 31

Other, smaller, way of microglia entering the brian?

Answer 31

Cells generated in the bone marrow go to the blood, then enter the brain, then become microglia