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Flashcards in Haem Deck (57):
1

Normocytic anaemia 6 weeks after flucloxacillin therapy

Autoimmune haemolytic anaemia

2

Osteopenia/lytic lesions + hypercalcaemia + rouleaux

Multiple myeloma

3

Target cells

Thalassaemia

4

Stomatocytes

Thalassaemia

5

Hypersegmented neutrophils

Megaloblastic anaemia

6

Heinz bodies and bite cells

G6PDH deficiency or pyruvate kinase deficiency

7

Jaundice after eating fava beans/ciprofloxacin/sulphonamide

G6PDH deficiency

8

Spherocytes

Hereditary or autoimmune haemolytic anaemia

9

Schistocytes

Microangiopathy (e.g. DIC) or intravascular prostheses

10

Haemolytic anaemia and aplastic anaemia after parvovirus infection

Sickle cell anaemia

11

Acanthocytes

Severe liver disease (hyperlipidaemia)

12

Cold-reacting antibodies (4)

  1. HIV
  2. Mycoplasma
  3. EBV
  4. Lymphoma

13

Reticulocytes

Haemolysis

14

Anaemia and peripheral neuropathy

B12 deficiency

15

Young boy with swollen knee

Haemophilia

16

Tissue death and bleeding in a septic patient

DIC

17

Jaundice and kidney failure after diarrhoea in child

HUS

18

FTL3 mutation

AML

19

Marrow >20% blasts

AML, ALL

20

TEL-AML1 mutation

ALL

21

Philadelphia chromosome/BCR-ABl/9 to 22

CML

22

Reed-Sternberg cells

Hodgkin lymphoma

23

Facial lymphoma caused by EBV

Burkitt's lymphoma

24

Starry sky appearance

Burkitt's lymphoma

25

Mesenteric lymphadenopathy

Non-Hodgkin lymphoma

26

CD 19, 20, 21, 23, 32, 25, 40

B cell neoplasm

27

CD 2, 3, 5, 7

T cell neoplasm

28

5q mutation

Myelodysplaia

29

Replacement of stem cells with fat in bone marrow

Aplastic anaemia

30

Pancytopenia in Ashkenazi Jew

Fanconi anaemia

31

JAK2 mutation

Myeloproflierative disorder (PV, ET, PMF)

32

Teardrop cells, blasts, gout and pancytopenia

Myelofibrosis

33

Pruritis, red skin and headache

PRV

34

Treat with Glivec (imatinib)

CML

35

SLE, livedo reticularis and recurrent miscarriage

Antiphospholipid syndrome

36

Lupus anticoagulant, anti-cariolipin, anti-B2-glycoprotein-I, anti-ApOH

Antiphospholipid sydrome

37

Pancytopenia, thrombosis, haemolytic anaemia and positive Ham test What's the treatment?

Paroxysmal nocturnal haematuria Ecluzimab

38

Hair-on-end skull, frontal and parietal bossing

Beta thalassaemia

39

Most common complication in multiple myeloma

Fractures

40

Iron-related complications of myelodysplastic diseases

Iron overload and refractory anaemia

41

Thrombosis 4 days after heparin

Heparin-induced thrombocytopenia

42

Afro-Caribbean

Sickle cell

43

Abdo pain + headaches after a respiratory infection

Sickle cell crisis

44

DRUG SE: folate deficiency (6)

  1. Sulfasalazine
  2. Trimethoprim
  3. Anticonvulsants
  4. Methotrexate
  5. Metformin
  6. OCP

45

Burr cells

Uraemia

46

Howell-Jolly bodies

Hyposplenism

47

Lymphoplasmacytoid cells

Waldenstrom's macroglobulinaemia

48

Osmotic fragility test

Hereditary spherocytosis

49

Cancer associated with pernicious anaemia

Gastric

50

Renal failure + light chains

Multiple myeloma

51

RA + splenomegaly + pancytopenia

Felty's syndrome

52

Hepatosplenomegaly + pigmentation + anaemia + pathological fractures

Gaucher's syndrome

53

Non-existent coagulation factor

VI

54

Monoclonal spikes

Multiple myeloma, MGUS

55

Bence-Jones proteins

Multiple myeloma

56

Pepperport skull (lytic lesions)

MM, hyperparathyroidism

57

Schilling test

B12