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Flashcards in Rheum/MSK Deck (50):
1

Anti CCP

RA

2

Anti dsDNA

SLE

3

Anti-Ro, anti-La

Sjogren's syndrome, SLE

4

Serum ACE

Sarcoidosis

5

Anti-centromere antibody

Limited scleroderma

6

Anti Jo-1

Polymyositis with lung involvement (may be dermatomyositis)

7

Negatively birefringent crystals under polarised light (needle-like)

Gout

8

Anti-cardiolipin

SLE + APLS

9

Heliotropic rash and Gottron's papules

Dermatomyositis

10

Headache, raised ESR, trouble getting out of chair

GCA with polymyalgia rheumatica

11

Anti-Smith

SLE

12

Global loss of joint motion with stiffness

Adhesive capsulitis

13

Anti-SCL-70 (anti topoisomerase)

Systemic sclerosis

14

Polyarthritis, conjunctivitis, urethritis

Reactive arthritis (can't see, can't pee, can't climb a tree)

15

Positively birefringent crystals under polarised light

Pseudogout

16

IgA with purpuic rash

Henoch-Schonlein purpura

17

Anti-GBM

Goodpastures

18

Shawl's sign

Dermatomyositis

19

Tensilon test

Myasthenia gravis

20

Wrist pain on forced thumb adduction and flexion

De Quervain's tenosynovitis

21

Prominent and tender tibial tubercle

Osgood-Schlatter's disease

22

Hypopigmentation + autoimmune disease

Vitiligo

23

Arthalgia + uveitis + orogenital ulcers

Behcet's disease

24

Positive Schirmer's

Sjogren's syndrome

25

Question mark posture

Ankylosing spondylitis

26

Arthralgia + reduced lung volumes

SLE

27

Obese boy - hip flexed, abducted and externally rotated

Slipped femoral epiphysis

28

Round-shouldered

Scheuermann's disease

29

Gold standard for diagnosing Sjogren's

Salivary gland biopsy (lymphocytic infiltrate)

30

Investigations for pathological fracture (2)

1. DEXA (OA)

2. CMP/Bence-Jones (myeloma)

31

Pencil in cup

Psoriasis

32

RA + splenomegaly

Felty's syndrome

33

Contortionist

Ehlers-Danlos syndrome

34

Back pain + TB

Pott's disease of the spine

35

Increased trabeular pattern and cortical thinking of the rigth hemipelvis with loss of joint space and osteophyte formation of the right hip

Paget's disease of bone

36

PAS positive macrophages in intestinal biopsies

Whipple's disease

37

Absent callus

Delayed union

38

Painful shoulder after seizure

Posterior dislocation

39

Twisting injury

Meniscal tear

40

Posterior fat pad sign

Radial head fracture

41

Cancer associated with Paget's disease of bone

Osteosarcoma

42

Gait seen in proximal myopathy

Waddling gait

43

Back pain + anterior uveitis

Ank spond

44

DRUG SE: nephrotic syndrome

Gold

45

DRUG SE: pulmonary and hepatic fibrosis

Methotrexate

46

DRUG SE: reversible oligospermia

Sulfasalazine

47

DRUG SE: gum hypertrophy

Ciclosporin

Others: phenytoin, calcium channel blockers

48

DRUG SE: exfoliative dermatitis

Gold

49

DRUG SE: irreversible retinopathy and alopecia

Hydroxychloroquine

50

DRUG: scleroderma crisis

ACE inhibitor