Flashcards in Hematology/Oncology Disorders Deck (95)
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61
translocation 9;22
CML philadelphia chromosome
62
most common form of hodgkin's lymphoma
nodular sclerosis
63
starry-sky pattern due to phagocytosis of apoptotic tumor cells
burkitt's lymphoma
64
high hematocrit/hemoglobin, pruritis, burnign pain in hands or feet
polycythemia vera
65
blood smear with hair-like projections, splenomegaly
hairy cell leukemia
66
antiretroviral that causes lactic acidosis
NRTIs
67
antiretroviral that causes GI intolerance
protease inhibitors
68
antiretroviral that causes pancreatitis
didanosine, stavudine, zalcitabine, ritonavir
69
antiretroviral that causes peripheral neuropathy
didanosine, stavudine, zalcitabine
70
antiretroviral that causes megaloblastic anemia
zidovudine
71
antiretroviral that causes rash
NNRTIs
72
antiretroviral that causes hyperglycemia, diabetes mellitus, and lipid abnormalities
protease inhibitors
73
antiretroviral that causes bone marrow suprression
zidovudine
74
antiretroviral that is given to pregnant women with HIV
HAART therapy +/- ziduvodine during labor
75
antiretroviral regimen for occupational HIV exposures
HAART: 2 NRTIS + NNRTI/protease inhibitor
zidovudine + lamivudine
76
antibiotic prophylaxis for HIV patients
< 200: TMP-SMX/dapsone for PCP
< 100: erythryomycin/clarithromycin for MAC
77
treatment for CLL
rituximab
78
no alpha-globin production, fetal death occurs
hydrops fetalis
4 abnormal alpha genes
79
minimal alpha-globin production, chronic hemolytic anemia, pallor, splenomegaly, microcytic RBCs on blood smear, decreased lifespan
hemoglobin H disease
3 abnormal alpha genes
80
reduced alpha-globin production, mild anemia, microcytic RBCs and target cells
alpha-thalassemia minor
2 abnormal alpha genes
81
generally asymptomatic hematologic disorder, children are at increased risk for alpha-thalassemia
alpha-thalassemia minima
1 abnormal alpha gene
82
no beta-globin production, asymptomatic until decline of fetal hemoglobin, growth retardation, increase in hemoglobin A2 and F, patients die in childhood without transfusions
beta-thalassemia major
2 abnormal beta genes
83
reduced beta-globin production, mild anemia, transfusions may be needed during periods of stress
beta-thalassemia minor
1 abnormal beta gene
84
treatment for anti-phospholipid syndrome
heparin, warfarin
hydroxychloroquine
85
prophylaxis when CD4 < 200
TMP-SMX for toxoplasmosis and PCP
86
treatment for porphyria cutanea tarda
phlebotomy and chloroquine
87
treatment for coxsackie virus herpangina
reassurance and symptomatic treatment
88
causes of distributive shock
sepsis, anaphylaxis, burns, adrenal insufficiency, drug reactions, and CNS injury
89
ovalo-macrocytes, leukopenia, thrombocytopenia, neutrophils with decreased segmentation
myelodysplastic syndrome
90
