Heme 1 Flashcards

(34 cards)

1
Q

most common type of hemophilia in the US

A

hemophilia A

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2
Q

hemophilia A

A

x linked recessive disease that predominantly affects males who have only one x chromosome - caused by factor VIII deficiency

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3
Q

s/sx of hemophilia A
6

A

easy bruising
excessive bruising
bleeding into joints (hemarthrosis)
delayed bleeding or bleeding for several hours to days
heavy menses
hematuria

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4
Q

hemophilia A labs - aPTT, PT, fibrinogen, plts

A

aPTT is prolonged
normal - PT, fibrinogen, plts

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5
Q

hodgkin’s lymphoma

A

cancer of the beta lymphocytes (B cells)

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6
Q

cancer of the beta lymphocytes (B cells)

A

hodgkin’s lymphoma

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7
Q

hodgkin’s lymphoma s/sx
6

A

night sweats
fevers
pain w/ alocholic drinks
pruritis
painless enlarged lymph nodes (neck)
anorexia

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8
Q

hodgkin’s lymphoma is identified by the presence of what cells

A

Reed-Sternberg cells

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9
Q

multiple myeloma

A

cancer of the plasma cells

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10
Q

cancer of the plasma cells

A

multiple myeloma

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11
Q

multiple myeloma s/sx
6

A

fatigue
weakness
bone pain usually in back or chest
proteinuria
hypercalcemia
normocytic anemia

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12
Q

common meds that can cause neutropenia
7

A

psychotropics
antivirals
abx
NSAIDs
antithyroids
ACEIs
propanolol

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13
Q

non-hodgkin’s lymphoma

A

a group of metalogic malignancies that are derived from B cell progenitors, T cells progenitors, mature B cells, mature T cells, or natural killer cells

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14
Q

usually occurs in older adults >65, presents with night sweats, fever, weight loss, and painless lymphadenopathy

A

non-hodgkin’s lymphoma

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15
Q

gradual onset of symmetric peripheral neuropathy starting in the feet and/or arms

A

vitamin b12 deficiency

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16
Q

vitamin b12 def - cells are micro or macro

17
Q

the proportion of RBCs in 1 mL of plasma

18
Q

micro value

19
Q

macro value

20
Q

average hgb content in a RBC

21
Q

the stored form of iron

A

serum ferritin

22
Q

most sensitive test for IDA

A

serum ferritin

23
Q

serum ferritin level - IDA

24
Q

serum ferritin level - thalasemmia

A

normal to high

25
serum iron level - IDA
decreased
26
serum iron level - thalassemia and macrocytic anemias
normal to high
27
immature RBCs that still have their nuclei
reticulocytes
28
gold standard test to dx hemoglobinopathies such as SCA, thalassemia, and more
hgb electrophoresis
29
order what two labs when evaluating MCV >100
B12 and folate levels
30
microcytic, hypochromic anemias 2
IDA thalassemia
31
B12 and folate def anemia size and color
macro, normo
32
anemia of chronic disease MCV and MCH
normalcytice, normochromic
33
SCA RBC normal life span
10-20 days
34
SCA MCV and MCH
normocytic/normochromic