High Risk & Multiple Gestation Flashcards

1
Q

Twin gestation account for how many of all live births in the US?

A

3.2%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Twins have a __ times greater chance of perinatal death than a singleton.

A

5

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Clinically, twin pregnancies present with symptoms of…

A
  1. increased MS-AFP
  2. earlier and more severe pelvic pressure causing hemorrhoids, constipation, backaches, shortness of breath
  3. increased fetal activity
  4. increased uterine size
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

T/F? The baby closer to the cervix is designated as Twin A.

A

true

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Twins are either monozygotic or dizygotic, depending on…

A

the number of eggs fertilized at conception.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

The term ‘zygosity’ refers to…

A

the number of zygotes involved.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

The term ‘chorionicity’ refers to…

A

the type of placentation in a twin pregnancy.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

T/F? The second trimester is the best time to determine chorionicity and amnionicity in multiples.

A

FALSE, first

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

In the first trimester, what do you look at to determine chorionicity?

A

The number of gestational sacs, amnions, and yolk sacs.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

In the 2nd & 3rd trimester, what do you look at to determine chorionicity?

A

The genders, the number of placentas, the appearance of the dividing membrane.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

If differing genders or two distinct placentas are noted then __chorionic placentation has occured.

A

di-

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

If the same gender and one placenta are noted, then what can we determine about the placentation?

A

It could be anything!! Look at the membranes next to narrow it down.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

T/F? The dividing membrane in a di-di gestation is only two layers thick.

A

FALSE, four layers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

T/F? The dividing membrane in a mono-di gestation is only two layers thick.

A

true

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

A cut-off level of greater than __ in septal thickness suggests dichorioncity.

A

2 mm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

The type of chorionicity in monozygotic twinning is determined by…

A

how early the twins divided from the single zygote.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Identical twins occur when the embryo splits between __ and __ days post conception.

A

2 and 14

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Identical twinning occurs in about __ pregnancies.

A

1/250

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

If the embryo splits before day 3, what kind of chorionicity results?

A

di-di

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

If the embryo splits between days 4 and 7, what kind of chorionicity results?

A

mono-di

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

If the embryo splits between 8 and 13 days, what kind of chorionicity results?

A

mono-mono

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

If the embryo splits after 14 days, what kind of chorionicity results?

A

mono-mono conjoined twins :(

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Di-di twins occur when the embryo splits before day…

A

3.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Mono-di twins occur when the embryo splits between day…

A

4 and 7.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Mono-mono twins occur when the embryo splits between day...
8 and 13.
26
Conjoined twins occur when the embryo splits after day...
14.
27
Mono-di twins have how many placentas?
one
28
Di-di twins have how many placentas?
Either two separate placentas or one big fused one.
29
From the __ weeks, the number of sacs and/or placentas is an accurate method for determining chorionicity.
6th through 10th
30
Diamnionicity occurs in __% of cases.
90%
31
Amnionicity is established by the number of...
yolk sacs and/or amniotic sacs.
32
If it's too early to identify the amnion, what can you use to determine amnionicity?
the number of yolk sacs
33
Mono-di twins have how many yolk sacs?
two
34
Mono-mono twins have how many yolk sacs?
one (or sometimes one partially divided yolk sac)
35
T/F? Identification of a single placenta differentiates between a monochorionic and a dichorionic gestation.
FALSE, does not differentiate
36
In the 2nd/3rd trimester, what 'sign' can we use to identify di-di twins?
'twin peak' or 'lamba' sign
37
T/F? Identification of two placentas differentiates between a monochorionic and a dichorionic gestation.
true
38
This is the most common kind of twinning.
mono-di
39
This is the least common kind of twinning.
mono-mono
40
The presence of more than three vessels in a cord is a strong indication of __ twins.
conjoined
41
With conjoined twins: the later the division of the embryo, the __ the number of shared organs.
greater
42
Conjoined twins are described by the...
site of union.
43
Thoracopagus twins are joined at the...
chest.
44
Pygopagus twins are joined at the...
sacrum.
45
Craniopagus twins are joined at the...
head.
46
Omphalpagus twins are joined at the...
abdominal wall.
47
Ischiopagus twins are joined at the...
pelvis.
48
The prognosis for conjoined twins is...
poor. Most are born prematurely, 40% are stillborn, and 35% die within a day.
49
Of the conjoined twins that survive, the riskiest separations involve a shared...
liver or heart.
50
Dizygotic ('fraternal') twins occur in about __ pregnancies.
1:83
51
Some factors associated with dizygotic twinning include...
1. recent cessation of long term oral contraceptives 2. maternal family history of multiples 3. maternal age 35-40 4. assisted reproduction
52
Is monozygotic or dizygotic twinning more common?
dizygotic
53
Dizygotic twinning is more common among __ than among caucasians.
african-americans
54
Women over __ have a higher incidence of dizygotic twinning.
40
55
Fetal growth discrepancy is defined as a greater than __ difference in the twins' estimated weight, __ or greater difference in the AC, and __ or greater difference in femur length.
20%, 20 mm, 5 mm
56
Fetal growth discrepancy is generally caused by...
1. placental insufficiency 2. death of one twin after week 16 3. chromosomal abnormalities
57
Fetal growth discrepancy can be described as mild (weight differences of __%) or severe (weight differences of __%).
15-25%, > 25%
58
This treatment consists of serial amniocenteses to normalize the intrauterine pressure, prevent premature labor, and relieve maternal symptoms.
therapeutic amniocentesis
59
The stress of a multiple pregnancy can affect the maternal respiratory, GI, renal & musculoskeletal systems causing...
1. preeclampsia 2. HTN 3. placenta abruption 4. hemorrhage 5. anemia 6. UTIs
60
This is the resorption of a non-viable fetus in a twin gestation.
vanishing twin
61
Sonographically, a vanishing twin is seen as...
1. a lack of multiple sacs on follow-up u/s 2. failure of sac growth in one twin 3. irregularly marginated sac 4. the 'vanishing' sac may mimic an implantation bleed in the cavity
62
This is a serious condition that occurs in monozygotic twins with a shared placenta.
twin to twin transfusion syndrome (TTTS)
63
TTTS is also known as...
'cross transfusion' or 'third circulation'
64
This results when the vascular supply of the twins develops an artery-to-vein anastomosis.
TTTS
65
T/F? Both twins are at risk of dying with TTTS.
true
66
Sonographically, the donor twin in TTTS is seen as...
1. small for dates 2. oligohydramnios 3. a 'stuck' twin with empty bladder and restricted movement**
67
The 'stuck' twin syndrome usually manifests itself between __ weeks gestation.
16-26
68
Sonographically, the recipient twin in TTTS is seen as...
1. hydropic (swollen) 2. ascites 3. enlarged liver, heart, and kidneys 4. polyhydramnios
69
This is the passage of thromboplastic material from a dead monochorionic twin to the remaining living twin through shared intraplacental vasculature.
twin embolization syndrome
70
Twin embolization syndrome can result in __ for the living twin.
neurological, GI, or genitourinary deficits***
71
Sonographically, the twin embolization syndrome is seen as...
1. intrauterine death of one twin** 2. hydrops 3. polyhydramnios 4. intraparenchymal hemorrhage 5. encephaly 6. enlarged, echogenic kidneys
72
This is a form of monozygotic twinning in which a severely malformed acardiac twin is perfused by the normal twin.
acardiac twin
73
Acardiac twin is also known as...
parabiotic twin.
74
The acardiac twin is often also...
aencephalic.
75
Perfusion of the acardiac twin is accomplished through what two kinds of anastomoses?
one vein-to-vein and one artery-to-artery
76
T/F? The normal co-twin in an acardiac pair has a typical level of risk.
FALSE, higher risk for CHF and hydrops
77
In this condition, the acardiac/acephalic twin receives all of its blood supply from the normal 'pump' twin.
Twin reversed arterial perfusion (TRAP sequence)
78
In TRAP sequence, blood enters the acardiac/acephalic twin through its umbilical __ and exits through the umbilical __.
artery/vein
79
T/F? TRAP sequence occurs only in a monochorionic gestation.
true
80
TRAP complicates approximately __ of monochorionic twins and 1:__ births.
1%, 1:35,000
81
Sonographically, TRAP sequence is seen as...
1. polyhydramnios 2. mono-di or mono-mono gestation 3. extremely malformed acardiac twin 4. hydropic pump twin
82
This is characterized by a macerated fetus, resulting from fetal death after it was too large to be reabsorbed.
fetus papyraceous
83
This is the term for when, hours after death, the skin of the fetus detaches from the underlying tissues.
'skin slippage'
84
This is a system designed to detect fetal asphyxia and assess fetal well being.
biophysical profile (BPP)
85
The BPP parameters are...
1. fetal breathing movements 2. gross body movements 3. fetal tone 4. amniotic fluid volume 5. non-stress test
86
In a BPP, fetal breathing must last at least...
30 seconds over a 30 minute period.
87
In a BPP, at least __ episodes of fetal body and/or limb movements must be seen over 30 minutes.
3
88
In a BPP, all fetal extremities should appear __ and the fetal chin __ OR at least __ episode of limb extension/flexion.
flexed, tucked to the chest; one
89
In a BPP, the amniotic fluid volume should exceed...
5 cm.
90
In a BPP, at least __ episodes of pulse acceleration of greater than __ over 30 minutes.
two, 15 bpm for 15 seconds
91
Fetal Doppler plays a vital role in the diagnosis of __ and in the assessment of __.
fetal cardiac defects and other non-cardiac malformations; the hemodynamic responses to hypoxia and anemia
92
Fetal Doppler measures the resistance of blood flow within the...
placenta.
93
Fetal Doppler has a good correlation between the absence of effective diastolic flow and...
poor outcomes.
94
This has a characteristic saw-tooth appearance of arterial flow in one direction and continuous umbilical venous flow in the other.
umbilical artery flow
95
With advancing gestation umbilical arterial Doppler wave forms demonstrate a progressive rise in __ and a decrease in __.
end-diastolic velocity, pulsatility index
96
Fetal Doppler of the umbilical vein showing pulsations later in pregnancy is an ominous sign that indicates...
CHF in a compromised fetus.
97
Cervical cerclage is most often recommended between __ weeks of pregnancy.
14-16
98
In this cervical condition, there are changes in the length and shape of the inner cervical os.
cervix funneling