Flashcards in Hist for Path: 2 Deck (22):
What do afferent arterioles arise from?
What do efferent arterioles arise from?
What is mesangial matrix?
- Area in glomeruli between capillaries that holds them together
What is name of smooth muscle in glomeruli that regulates blood flow and filtration?
3 functions of mesangium?
1. Contraction to regulate flow: smooth muscle cell
2. Structural support
Where are the fenestrations found?
- Cell walls of endothelial cells
What does basement membrane divide?
Extracapillary: Urinary space
What is in visceral epithelium?
What is in between foot processes of epithelium?
What is the glomerular filtration barrier?
"Glomerular basement membrane" made of:
1. Basal lamina of endothelial
What does glomerular membrane prevent from filtering?
1. Large molecules: Proteins
2. Negative molecules: albumin
What is immunofluorescence used to detect?
Components of the nephron?
2. Prox tubule
Where does the distal tubule pass?
Near the glomerulus
Which tubules have wider lumen?
What structures are not found in medulla?
2. Proximal tubule
3. Distal tubule
What is found in medulla?
1. Loop of henle
2. Collecting ducts
What is found on surface of proximal tubule?
- Brush border greatly increasing resorptive ability
What is the macula densa?
- Region of distal tubule that runs by glomerulus
What is the JG apparatus?
- Formed by distal tubule and afferent arteriole
- Regulates BP and filtration rate
- Regulates based upon distal  of NaCl
What is loss of glomerular slit diaphragms and appearance of a continuous layer of podocyte cytoplasm indicative of?