Histology: Connective Tissue (lab) Flashcards Preview

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Flashcards in Histology: Connective Tissue (lab) Deck (33)
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1

What cells appear granular and blue as a result of ferritin injection and prussian blue die?

Macrophages

2

Compare loose connective tissue to dense connective tissue?

typically has more cells and less ECM

3

These cells have elongated nuclei that are typically larger and paler than that of macrophages?

Fibroblasts

4

Compare the nuclei of mesothelial cells to Fibroblast nuclei?

These are larger and more pale than fibroblasts

5

What cells appear red and are full of naturally occuring granules?

Mast cells

6

What cells have spotty looking nuclei with 3 to 5 lobes?

Granulocytes/Neutrophils

7

What makes up the mononuclear phagocytic system throughout the body?

Macrophages

8

What is the job of macrophages?

clean up of debris
Remodeling after injury
monitoring of the body through the innate immune system

9

T or F: Macrophages have antigens presented on their surface to the adaptive immune system by membrane proteins?

True

10

What are the types of membrane proteins presented on the macrophage?

major histocompatibility complex (MHC) or human leukocyte antigen (HLA)

11

When do macrophages become activated?

by injection or infection by foreign substances

12

What are macrophages in the hepatic sinusoids called?

Kupffer cells

13

T or F: in healthy mesentery tissue a large number of macrophages will be present?

False

14

What tissues typically have a larger number of macrophages?

Hepatic sinusiods, Alveolar walls, and Red pulp of the spleen

15

What cells are macrophages derived from?

Monocytes

16

What is a characteristic of macrophages in the lungs?

They might appear black because of carbon in the cytoplasm

17

In skin the nuclei around dense green collagen fibers are most likely....

Fibroblasts

18

Where are plasma cells commonly found?

Under the epithelium in G.I. tract, Bone marrow, and respiratory tract

19

What are the distinguishing features of the plasma cell?

round nucleus (off center), Heterochromatin clumped like a clock face, pyramid cytoplasm, basophilic cytoplasm

20

What color does collagen appear in H & E?

pink, sometimes hard to tell from smooth muscle

21

How do elastic fibers appear in H & E?

Thin dark streaks, while collagen is thicker and lighter (in unsectioned tissue)

22

What color stain is used to distinguish elastic tissue from collagen?

dark purple

23

What kind of type of fibers are often visualized using silver staining?

Reticular fibers (appear as black threads)

24

Where are reticular fibers common?

Stroma of the lymph node

25

What type of connective tissue predominates in mesentery?

Loose connective tissue - lots of space between collagen fibers

26

Where can dense irregular connective tissue often be found?

Surface of the skin, capsules of organs

27

Where is dense regular connective tissue often found?

Muscles, tendons, aponeurosis

28

What are the two components of tendon?

fibroblasts, collagen

29

What type of fiber secreting cells can be found within a lymph sinus with H&E stain?

reticular cells - elongated nucleus

30

T or F: reticular cells can be visualized with silver stain?

False - reticular fibers CAN be visualized with silver stain