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ICM Infectious Disease > HIV > Flashcards

Flashcards in HIV Deck (36):
1

What were the "4 H's"?

Heroin, Homosexual, Haitains, and Hemophilliac

2

How is HIV screen for now?

HIV RNA (plasma)

3

How long until 3rd generation antibody tests can detect HIV?

10 days

4

Most commonly reported symptom of HIV?

Fever and fatigue

5

Can a low CD4 cell count be diagnostic of HIV?

No, have to use HIV antibody testing

6

What happens if the ELISA test is positive?

You do it again.

7

What happens if 2nd ELISA test is positive?

You run a Western Blot test

8

What is the main marker for HIV disease progression?

CD4

9

Normal range of CD4?

350 to 1100/mm3

10

How can we measure viral RNA in plasma?

PCR or branched DNA techniques

11

How will HIV present at CD4 count >500/mm3?

Asymptomatic

12

How will HIV present at CD4 count 500-200?

Asymptomatic, generalized adenopathy, thrush, and Kapok's sarcoma

13

CD4

PCP, toxoplasmosis, and cryptococcus

14

CD4

CMV and mycobacterium increased risk

15

When do you start HIV treatment?

CD4 cell count

16

What is Lipodystrophy syndrome?

Body morphology changes and metabolic complications

17

Where is AIDs the worst?

Sub-Sahara Africa

18

How did HIV spread?

Africa to Haiti and then Haiti to U.S

19

Easiest way to get HIV?

Blood transfusion (90%)

20

Hardest way to get HIV?

Insertive oral intercourse (0.005%)

21

How often should you screen people at high risk for HIV?

Once a year

22

What are two HIV opportunistic associated diseases?

Pneumocystis pneumonia
Kaposi's sarcoma

23

An abrupt onset of 10 signs and symptoms in 24 hours would be indicative of what?

Primary HIV infection

24

What is the highly sensitive screen test used for HIV antibody testing?

ELISA (Enzyme linked immunosorbent assay)

25

What happens if the ELISA comes up as negative?

HIV antibodies reported as negative

26

What happens if the ELISA comes up as positive?

You repeat it a second time

27

What happens if the second ELISA test is positive?

You do a western blot test

28

What constitutes a positive WB test?

2 of the 3 specific bands show up

29

How do you measure viral RNA in plasma?

PCR or branched DNA techniques

30

What type of vaccines do you want to avoid giving an HIV patient?

Live

31

Which pathogen has the highest risk of seroconversion after percutaneous exposure?

Hep B (30%)

32

Was Zidovudine protective against HIV?

yes

33

Was is the correlation between HIV viral load and % to transmit to newborn?

The higher the HIV viral load the higher the likelihood to transmission

34

LDH value in Pneumocystis Pneumonia patients?

Elevated

35

How do you treat Pneumocystis Pneumonia?

Corticosteroids or antimicrobials

36

CD4 count less than 50 leads to what?

CMV and mycobacterium avid complex
Increased risk of lymphoma
Highest mortality