Osteoporosis Flashcards Preview

ICM Infectious Disease > Osteoporosis > Flashcards

Flashcards in Osteoporosis Deck (20):
1

What characterizes Osteoporosis? (4)

Low bone mass
Deterioration of bone tissue
Compromised bone strength
Increased risk of fracture

2

What factors determine peak bone mass? (4)

Genetics
Nutrition
Endocrine status
Physical activity and health during growth

3

Increased bone loss by? (4)

Aging
Hypogonadism
Menopause
High bone turnover

4

Osteoclastic activity?

Removing older bone

5

Osteoblastic activity?

Replacing old bone with new bone

6

Where are the changes in osteoporosis?

Cancellous bone
Thinning of trabeculae

7

Women of what age are more at risk?

Over 50, postmenopausal

8

What dietary inadequacies can cause osteoporosis? (4)

Low calcium
Low Vit D
Excess Vit A
Excess salt

9

Cystic fibrosis causes a problem with what in bones?

Absorption

10

Turners is what chromosome defect?

XO

11

Klinefelter's are what chromosome problem?

XXY

12

Cushing's syndrome or exogenous corticosteroids cause whaT?

Corticosteroid excess

13

Hyperparathyroid results in what?

Too much calcium taken from the bone

14

Gastrointestinal disorders affect what in osteoporosis?

Absorption

15

Fractures of dorsal spine can lead to what?

Increasing kyphosis

16

Main screen and diagnostic study for osteoporosis?

DEXA (Dual xray absorbiometry

17

DEXA is based on what?

Density, not morphology

18

What is osteomalacia?

Impaired mineralization of the bony matrix

19

Neoplasm metastatic to bone can cause what?

Compression fractures

20

Therapy? (2)

Weight bearing
Muscle strengthening exercise