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ICM Infectious Disease > Staph infections > Flashcards

Flashcards in Staph infections Deck (51):
1

Staph Gram + or -?

+

2

Staph catalase + or -?

+

3

Staph aureus coagluase + or -?

+

4

Staph Epidermis coaglusase + or -?

-

5

Staph aureus shows up how on blood agar?

Golden beta hemolytic colonies

6

Coagulase - staph shows up how on blood agar?

Small white non hemolytic colonies

7

Most virulent of staph species?

Staph aureus

8

How do staph epidermis infections usually happen?

Prosthetic devices

9

Is staph aureus part of normal flora?

Yes

10

Rate of colonization of S. aureus greater in who?

Diabetes patient
HIV patient
Skin damage

11

Diseases that cause increased risk for S. aureus?

Chronic granulomatous disease
Job's/Chediak-Higashi syndrome

12

Majority of MRSA cases are confined to where?

Skin and soft tissue (not that dangerous)

13

Pyogenic organisms cause what?

Abscesses

14

3 Toxins produced by Staph?

1) Cytotoxins
2) Pyogenic toxin superantigens
3) Exfoliative toxin

15

Pyogenic toxin superantigens mediate what two problems?

Food borne illness
Staph toxic shock syndrome

16

In staph food borne illness what gives the clue that it's staph?

Symptoms in absence of viable bacteria

17

Where is toxin produced in toxic shock syndrome?

Site of colonization

18

IS there a staph vaccine?

No

19

Are anti-staph antibodies beneficial?

Only in-vitro so far

20

Infection of epidermis?

Impetigo

21

Infection of superficial dermis?

Folliculitis

22

Infection of deep dermis?

Carbuncles, furuncles, and abscess

23

Pyomyositis?

Infection of skeletal muscle

24

Cellulitis, erysipelas, and fascitisi?

Infection of subcutaneous tissue

25

Hidradenitis suppurativa?

Follicular infection of intertriginous areas

26

Staph sepsis usually produced by what?

Bacteremia

27

Leading cause of community acquired and healthcare acquired bacteremia?

Staph

28

3 categories of acquired zones?

1) Healthcare associated (nosocomial)
2) Community acquired
3) Healthcare associated community onset (long term care facility)

29

Infective endocarditis causes what growths that destroy heart valves?

Vegetations

30

How long for duration of therapy for uncomplicated infection?

14 days of IV therapy

31

What is SIRS?

Systemic inflammatory response syndrome, clinical syndrome complicating a nonifectious insult

32

What is septic shock?

Sepsis induced hypotension persisting despite adequate fluid resuscitation

33

Frequency of pathogens?

Gram + > Gram - > Fungals

34

To do list for septic patient?

Source of infection
Check respiratory status
Check perfusion
Check end organ effects

35

At what point is mortality establish as highest?

Septic shock

36

Methicillin resistance medicated by?

PBP-2a (Penicillin binding protein encoded by mecA)

37

Where is mega gene>

Mobile genetic element

38

Big risk factor for MRSA?

Recent antibiotic therapy

39

Which two antibiotics are especially correlated with MRSA?

Cephalosporin
Fluoroquinolone

40

Which is higher? Death rates from hospital acquired MRSA or community acquired?

Hospital acquired

41

When do MRSA infections show up in hospital acquired?

Healthcare acquired community onset

42

Key interventions Billings Clinic used>

Hand hygiene
Decontamination of environment
Contact precautions
Active surveillance cultures

43

Next threat on the horizon in terms of resistant staph?

Vancomycin resistant S. aureus

44

Staphylococcal scalded skin syndrome caused by?

Exfoliative toxin from Staph

45

S. aureus meningitis most commonly occurs with what?

Head trauma
neurosurgery

46

Abdominal pain in left upper quadrant is indicative of what in staph bacteremia?

Splenic abscess/infarction

47

What do you give as treatment before blood cultures are back?

Empiric antibiotic therapy
Vancomycin

48

If cultures come back as methicillin sensitive what do you give

Nafcillin
Oxacillin
Cefazolin
Penicillinase resistant penicillin

49

What do you give for meth resistant Staph?

Vancomycin

50

Diagnostic criteria for SIRS?

Temp > 38
HR > 90
RR > 20
WBC >12k 10% immature bands
SBP

51

Vasodilatory shock?

Sepsis induced hypotension persisting despite adequate fluid resuscitation