Rheum in STEP 1 Book (2) Flashcards Preview

ICM Infectious Disease > Rheum in STEP 1 Book (2) > Flashcards

Flashcards in Rheum in STEP 1 Book (2) Deck (19):
1

Sarcoidosis characterized by what?

Immune mediated widespread noncaseating granulomas
Elevated Serum ACE levels
Elevated CD4/CD8 ratio

2

Common symptoms of Sarcoidosis?

Usually asymptomatic besides enlarged lymph nodes

3

What will sarcoidosis look like on CXR?

Bilateral adenopathy and coarse reticular opacities

4

Sarcoidosis is associated with what lung problem?

Restrictive lung disease due to interstitial fibrosis

5

Treatment for Sarcoidosis?

Steroids

6

What is Polymyalgia rheumatica?

Pain and stiffness of shoulders an hips with fever, malaise, and weight loss

7

Polymyalagia rheumatica associated with what?

Giant cell arthritis

8

Lab findings in Polymyaliga rheumatica?

Increased ESR, increased CRP, and normal CK

9

Treatment of Sarcoidosis?

Low dose corticosteroids

10

Fibromyalgia associated with?

Chronic widespread musculoskeletal pain associated with stiffness, paraesthesias, poor sleep, and fatigue

11

How do you treat fibromyalgia?

Exercise
Antidepressants
anticonvulsants

12

Polymyositis characterized by what?

Progressive symmetric proximal muscle weakness with endomysial inflammation with CD8 T cells, most often hits shoulders

13

Dermatomyositis characterized by what?

similar to polymyositis, but with a malar rash
Grotton papules
Shawl and Face rash
Erythematous rash

14

Scleroderma triad?

Autoimmunity
Non-inflammatory vasculopathy
Collagen deposition with fibrosis

15

Common manifestations of Scleroderma?

Puffy taut skin without wrinkles
Fingertip itting
Sclerosis of Renal, pulmonary, cardiovascular, and GI systems

16

2 Major types of Scleroderma?

Diffuse
Limited

17

Characteristics of Diffuse Scleroderma?

Widespread skin involvement
Rapid progression
Anti Scl-70 antibody (anti-DNA topoisomerase 1)

18

Limited Scleroderma characteristics?

Limited skin involvement confined to fingers and face
CREST invovlement (Calcinosis, Raynauds, Esophageal dysmotility, Sclerodactyl, Telangeictasia

19

Limited Scleroderma associated with what antibody?

Anti-centromere antibody