Flashcards in Rheum in STEP 1 Book (2) Deck (19):
Sarcoidosis characterized by what?
Immune mediated widespread noncaseating granulomas
Elevated Serum ACE levels
Elevated CD4/CD8 ratio
Common symptoms of Sarcoidosis?
Usually asymptomatic besides enlarged lymph nodes
What will sarcoidosis look like on CXR?
Bilateral adenopathy and coarse reticular opacities
Sarcoidosis is associated with what lung problem?
Restrictive lung disease due to interstitial fibrosis
Treatment for Sarcoidosis?
What is Polymyalgia rheumatica?
Pain and stiffness of shoulders an hips with fever, malaise, and weight loss
Polymyalagia rheumatica associated with what?
Giant cell arthritis
Lab findings in Polymyaliga rheumatica?
Increased ESR, increased CRP, and normal CK
Treatment of Sarcoidosis?
Low dose corticosteroids
Fibromyalgia associated with?
Chronic widespread musculoskeletal pain associated with stiffness, paraesthesias, poor sleep, and fatigue
How do you treat fibromyalgia?
Polymyositis characterized by what?
Progressive symmetric proximal muscle weakness with endomysial inflammation with CD8 T cells, most often hits shoulders
Dermatomyositis characterized by what?
similar to polymyositis, but with a malar rash
Shawl and Face rash
Collagen deposition with fibrosis
Common manifestations of Scleroderma?
Puffy taut skin without wrinkles
Sclerosis of Renal, pulmonary, cardiovascular, and GI systems
2 Major types of Scleroderma?
Characteristics of Diffuse Scleroderma?
Widespread skin involvement
Anti Scl-70 antibody (anti-DNA topoisomerase 1)
Limited Scleroderma characteristics?
Limited skin involvement confined to fingers and face
CREST invovlement (Calcinosis, Raynauds, Esophageal dysmotility, Sclerodactyl, Telangeictasia