HUNTINGTON DISEASE Flashcards
(9 cards)
1
Q
Huntington disease is a chronic, progressive, hereditary disease of the nervous system that results in progressive involuntary
A
choreiform movement and dementia
2
Q
Huntington Disease is transmitted by
A
autosomal dominant gene
3
Q
In huntington disease, pathology involve premature death of cells in the
A
Striatum (Caudate and Putamen) of the basal ganglia.
4
Q
a building block for protein, abnormally collects in the cell nucleus, causing cell death.
A
Glutamine
5
Q
Most prominent clinical manifestation of huntington disease
A
Choreiform movement
6
Q
what genetic marker is present in Huntington disease?
A
Cytosine-adenine-guanine
7
Q
Huntington Gene
A
(HTT)
8
Q
Treatment for Chorea
A
Tetrabenazine
9
Q
motor restlessness
A
Akathisia
