Flashcards in Hypertension Deck (72)
What do you use with reserpine and guanethdine to avoid fluid retention?
a diuretic pref a thiazide
What are the potential adverse effects of diuretics?
What are two aldosterone antagonists?
What are the mechanism of ACE inhibtitors?
block bradykinin degradation which stimulate syntehsis of other vasodilating substances like PGE2 and prostacyclin
blocks conversion of angiotensin I to angiotensin II
What disease can ACE inhibitiors it prevent or regress?
left ventricular hypertrophy
What are the adverse effects associated with ACE inhibitors?
neutropenia, agranulocytosis, proteinuria, glomerulonephritis, acute renal failure
What is the angiotensin II receptor blocker?
ARB, don't block bradykinin breakdown
less cough than ACE inhibitor
What is the renin inhibitor?
aliskiren; angiotensinogen to angiotensin I inhibitor
What are the precautions needed to be taken with ACE inhibitor or arbs?
can cause kidney failure
in pts with severe bilateral renal artery steoniss
What drug should you use in hypertensive emergency?
Combination therapy usually involves what?
two or more agents to control HTN
one should be a thiazide unelss contraindicated