Hyperthyroidism Flashcards
(20 cards)
It is a form of thyrotoxicosis resulting from excessive synthesis and secretion of endogenous or exogenous thyroid hormones by the thyroid
HYPERTHYROIDISM
Common causes of hyperthyroidism
- Graves disease
- Toxic multinodular goiter
- Toxic adenoma
- Thyroiditis
- Excessive ingestion of thyroid hormone.
Distinguishing signs & symptoms of HYPERthyroidism
- Tachycardia / palpitations
- Heat intolerance w/ increased perspiration
- Weight loss
- Diarrhea
- Thin skin
- Exopthalmos
- Goiter
- Oligomenorrhea
What is the most common form of treatment for Graves disease?
RADIOACTIVE IODINE
What are the beta-adrenergic blocking agents used to treat hyperthyroidism
- Propranolol
- Atenolol
- Metoprolol
3 common tx for hyperthyroidism
- Radioactive iodine therapy
- Antithyroid
- Medications (ex. thionamides)
- Subtotal Thyroidectomy
Patients with Graves disease may sustain remission for up to ____ to ____ months
12-18 months
What radiation isotope is used for irradiation / radiation iodine therapy?
RADIATION 131 I
> Considered the treatment of choice due to its high efficacy
> Used to treat toxic adenomas, toxic multinodular goiter, and various forms of thyrotoxicosis.
RADIOACTIVE IODINE THERAPY (RAI)
These medications that interfere with the synthesis of thyroid hormones and other agents that control manifestations of hyperthyroidism.
ANTITHYROID MEDS
What is the MOA of radioactive iodine 131 I?
It targets thyroid cells, destroying them without affecting other tissues
For breastfeeding moms, how many weeks is it contraindicated prior to treatment to prevent infant exposure?
6 WEEKS
Must have a negative pregnancy test ____ hours before treatment and avoid conception for at least _____ months post-treatment.
48 HOURS; 6 MONTHS
Indications of RAI
- Graves disease
- Toxic multinodular goiter
- Toxic adenomas
Thyroid storm is characterized by:
- Hyperpyrexia (>38.5 C)
- Extreme Tachycardia (>130 bpm)
What medication is contraindicated for hyperthyroidism because the displace thyroid hormone from binding proteins and worsen the hypermetabolism.
SALICYLATES (ASPIRIN)
It is a form of severe hyperthyroidism, usually of abrupt onset.
THYROID STORM OR THYROTOXICOSIS
Surgery for treatment of hyperthyroidism
SUBTOTAL THYROIDECTOMY
Signs of heart failure
- dyspnea
- jugular vein distention
- crackles
- peripheral edema
is the drug of choice to reduce elevated body temperature
ACETAMINOPHEN
