Immunology 3

Question 1

found on surface of Dane particle

Answer 1

HBsAg

Question 2

foundin the body fluids of patients with HBV

Answer 2

hbsag

Question 3

first marker to appear in serum (2-12wks)

Answer 3

hbsag

Question 4

indicator of active infection

Answer 4

hbsag

Question 5

scrng blood donors

Answer 5

hbsag

Question 6

indicates high infectivity and very high transmission (serum)

Answer 6

hbeag

Question 7

present during periods of “active replication” of virus

Answer 7

hbeag

Question 8

not detectablein serum bec of viral env

Answer 8

hbcag

Question 9

detected only in hepatocytes (liver biopsy)

Answer 9

hbcag

Question 10

total ab to hbcag

Answer 10

anti-hbc total

Question 11

used as a marker of acute or chronic hbv infection and a life long marker of past exposure to HBV

Answer 11

anti-hbc total

Question 12

used as a marker of acute hbv infection

Answer 12

anti-hbc igm

Question 13

indicator of present or current infection

Answer 13

anti-hbc igm

Question 14

detect core window period

Answer 14

anti-hbc igm

Question 15

persists for the lifetime of the individual

Answer 15

anti-hbc igg

Question 16

predominant antibody detected in the test for total anti-hbc

Answer 16

anti-hbc igg

Question 17

marker for chronic hepatitis

Answer 17

anti-hbc igg

Question 18

marker of convalescence and favorable prognosis

Answer 18

anti-hbe

Question 19

low infectivity of blood

Answer 19

anti-hbe

Question 20

px is recovering from hbv infxn

Answer 20

anti-hbe

Question 21

used as a marker of past infxn and also a marker of immunity (immune state)

Answer 21

anti-hbs ab

Question 22

response to vaccination

Answer 22

anti-hbs ab

Question 23

vacci scr and post-vacci follow up

Answer 23

anti-hbs ab

Question 24

hepa C dx test

Answer 24

RIBA

inc ALT

Question 25

hepa E dx marker

Answer 25

antiHEV igM -acute | HEV RNA -detected in feces (PCR)

Question 26

manifes of IM

Answer 26

leukocytosis >50% lymphocytes downey cells atypical reactive lymphocytes

Question 27

heterophile ab

Answer 27

forssman ha serum sickness ha IM ha

Question 28

sero test for HA

Answer 28

paul-bunnel SHEEP davidsohn differential test monospot/rapid differential slide test HORSE

Question 29

ENV hiv codes for gp__ - - -

Answer 29

gp160 gp120 (knobs/spikes) gp41 (spans inner and outer mem)

Question 30

GAG codes for 3 structural proteins

Answer 30

p55 p24 p17

Question 31

POL codes for enz necessary for replication - cleaves structual proteins - transcribe RNA to DNA - inserts viral DNA to host DNA

Answer 31

p66 p51 Protease Reverse transcriptase Integrase

Question 32

HIV ab detection scr | confirm

Answer 32

``` scr ELISA Microfiltration EIA Agglu test ---- confirm WESTERN BLOT IFA RIP ```

Question 33

wetern blot bands

Answer 33

p24 gp41 gp120/gp160