Infection - TB Flashcards

1
Q

TB initial phase tx and duration

A

RIPE
- rifampicin
- isoniazid
- pyrazinamide
- ethambutol
TWO MONTHS

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2
Q

TB continuous phase tx and duration

A
  • rifampicin
  • isoniazid
    FOUR MONTHS
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3
Q

latent TB tx and duration

2 options

A
  • 3 MONTHS of rifampicin and isoniazid
  • 6 MONTHS of isoniazid
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4
Q

what needs to be cleared before giving TB medication?

and age

A

hepatotoxicity in 35-65yr

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5
Q

s/e and interaction of rifampicin

A
  • discolour soft contact lesnes + bodily fluids orangey red
  • CYP450 enzyme inducer
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6
Q

s/e of isoniazid

A
  • peripheral neuropathy
  • cyp450 inhibitor
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7
Q

tx of peripheral neuropathy

A

prophylactic pyridoxine HCL (vit b6) given

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8
Q

s/e of pyrazinamide

A

heptatotoxic

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9
Q

s/e of ethambutol

A
  • visual impairment
  • ocular toxicity
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