Infectious Dz Lab Interpretation

Question 1

What does the in-house SNAP 4Dx Plus test for?

Answer 1

(Heartworm (antigen), lyme (antibodies), Ehrlichia canis and ewingii (antibodies), and Anaplasma platys and phagocytophilum (antibodies))

Question 2

What infectious agents cause morulae in neutrophils on blood smear?

Answer 2

(Ehrlichia ewingii and Anaplasma phagocytophilum)

Question 3

(T/F) The quantitative C6 lyme test only confirms exposure.

Answer 3

(T, it is an antibody test, though you will be given reference intervals that indicate if an true infection is more likely or not)

Question 4

IgG antibodies for RMSF infections do not increase until how many weeks post infection?

Answer 4

(2-3 weeks, a single titer needs to be >1024 to be considered positive for infection or can do convalescent titers → 4x increase indicates infection)

Question 5

IgM antibodies for RMSF infections increase within how many weeks of infection?

Answer 5

(1 week)

Question 6

How long can Ehrlichia canis positive antibody titers persist post treatment and resolution of clinical signs?

Answer 6

(Months to years)

Question 7

What sample(s) should be collected to submit for PCR in a dog you suspect has leptospirosis?

Answer 7

(Blood and urine)

Question 8

You run a Witness IgM test on a dog you suspect has leptospirosis, it comes back positive, what additional information do you want to know prior to trusting this test is true?

Answer 8

(If the dogs has been vaccinated for lepto in the past 3-6 months, if so it could be the vaccination (need further testing), if not you can believe the test)

Question 9

(T/F) A negative Blastomyces urine antigen test helps you to rule out the presence of a fungal infection.

Answer 9

(T)

Question 10

In addition to confirming there is a fungal infection in your patient, how else is a fungal urine antigen test useful?

Answer 10

(It can be run throughout treatment, it should decrease to indicate the treatment is working)