infective endocarditis Flashcards
what is effective endocarditis
infection involving the innermost layer of the heart
in what ways can endocarditis be contracted
older patients with degenerative heart disease (aortic) stenosis
healthcare procedures
intra cardiac device
valve disease
prothetelic valve
what are the risk factors of endocarditis
mitral valve disease
rheumatic heart disease
congenital heart disease
symmetric septal hypertrophy
what is the basic pathophysiology of infective endocarditis
normal valve endothelium resistant
endothelial disruption - expose extracellular matrix
deposition of fibrin and platelets
bacteria adhere to the thrombus, and grow
what causes damage to the endothelium
turbulent blood flow
electrodes
catheters
inflammation - caused by rheumatic carditis
degenerative valve disease
what are some common symptoms of infective endocardidtis
fever and chilis
night sweats
weight loss
fatigue
weakness
SOB
what are the sings of Infective endocarditis
cardiac murmur - regurgitate - heart failure
Janaway lesions
splinter haemorrhage
bacteraemia with murmur
what are the investigations of infective endocarditis
blood culture
FBC
WBCs
U+Es
urinalysis
ECG - PR prolongation
Chest X-ray - pulmonary congestion
what is the treatment for infective endocarditis
targeted antibiotics (often bacterial infection )
why have preventative measures
outcomes are poor
15-30% mortality
what are some preventative measures
prophylactic antibiotics
good dental hygiene
disinfect wounds
curative antibiotics when getting a infection
