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Flashcards in Integument II Deck (21):
1

Sebaceous glands

-Holocrine glands
- branched acinar glands with short ducts
- found everywhere except palms and soles
- continuously produce sebum
- released into hair follicle
- Growth is stimulated at puberty by sex hormones

2

Sebaceous glands continually secrete

Sebum

3

Sebum is released into

hair follicles

4

Sebaceous glands use what type of secretion

holocrine

5

Sweat (sudoriferous) glands are what type of glands (secretion)

-both merocrine and apocrine glands

6

Merocrine sweat (sudoriferous) glands

-Coiled, simple tubular secretory portions:
- Lined by simple epithelium
- Apical dark secretory cells secrete glycoproteins
- Basal clear cells secrete water and electrolytes
- Myoepithelial cells (found between the basal lamina and the basal domain of clear cells)
- Duct system consists of stratified cuboidal epithelium except in epidermis
- Cholinergic endings

7

Apocrine sweat (sudoriferous) glands

- found in labia major, areola, and axillary and anal regions
- secretions are thicker and more viscous than merocrine types
-excretory duct opens into hair follicle
- Adrenergic innervation
- inactive until puberty
- Special types: Ceruminous glands, Glands of Moll

8

What are the two special types of apocrine sweat glands

-Ceruminous glands
- Glands of Moll

9

apocrine sweat glands have what type of secretion

Although called apocrine the name is a incorrect interpretation that the apical domain of the secretory cells is shed during secretion. These sweat glands release their secretion by a merocrine process

10

Development of hair follicle

Develop from epidermis as elastic, keratinized threads

11

Components of hair follicle

-Root
-Free shaft
- Hair follicle

12

____ glands and ______ muscles are associated with hair follicles

sebaceous glands, arrector pili

13

Hair bulb

-Expanded lower part of hair follicle
- Matrix
- Vascularized dermal papilla

14

epithelial cells covering the apex of the dermal papilla give rise to the _____ of the hair. cells at the sides give rise to the hair ____.cells at the margin form the _____

Medulla of hair, Hair cortex, cuticle

15

Patients with _____ syndrome have silvery hair because of a mutation in the myosin Va gene involved in the transport of melanin-containing melanosomes

Griscelli

16

The external root sheath of hair follicle

down growth of epidermis

17

Internal root sheath of hair follicle

-Generated by bulb
- Layers:
- Henle's layer (outermost)
- Huxley's layer
- Cuticle
- Interlocks with cuticle of hair shaft

18

What are the layers of the hair shaft

-medulla (innermost
- Cortex
- Cuticle

19

What cells can reestablish epidermis in severely burned patients

Keratinocyte stem cells

20

Migration pathways for keratinocyte stem cells

-bulb-epidermis stem cell pathway
- bulb-sebaceous gland stem cell pathway
- bulb-hair stem cell pathway

21

Signaling pathways for Keratinocyte stem cells

-Wnt signaling pathway
- Notch signaling pathway