Upper GI II Flashcards Preview

Histology Exam III Material > Upper GI II > Flashcards

Flashcards in Upper GI II Deck (36):
1

________ opens into bottom of gastic pit

Narrow isthmus

2

______ of the gastric gland extends into the lamina propria

Fundus (base)

3

Cells of the gastric gland

-mucous neck cells
- Stem cells in neck
- Chief cells (zymogenic cells)
- Parietal cells (oxyntic cells)
- Enteroendocrine Cells (APUD cells)

4

Mucous neck cells of the gastric glands secrete

soluble mucous

5

Chief cells (zymogenic cells) secrete

Pepsinogen

6

Parietal cells (oxyntic cells) manufacture _______ and secrete ______

Manufacture HCl (note that they secrete H+ and Cl-)
They secrete intrinsic factor

7

Enteroendocrine cells (APUD cells) function of gastric glands

-secrete hormones
- Amine Precursor uptake and decarboxylation

8

Parietal cells are unique cell of the

gastric gland

9

Histological characteristics of parietal cells

Large pyramidal shaped, eosinophilic cell

10

Parietal cells produce ______ and secrete ____-

Produce HCl
Secrete intrinsic factor

11

Parietal cells generate hydrogen ion from _______ similar to osteoclast

carbonic acid

12

Parietal cells have prominent __________ lined by ______

Parietal cells have a prominent intracellular canaliculi lined by microvilli

13

_________ of the parietal cells are part of exocytosis-endocytosis funciton

Turbulovesicle pools

14

Function of gastric intrinsic factor secreted by parietal cells

necessary for absorption of Vitamin B12 by the ileum

15

Chief cells secrete

pepsinogen

16

small cells of gastric glands with secretory vesicles polarized toward basal surface in proximity to blood vessels

Enteroendocrine (APUD cell)

17

The enteroendocrine cell (APUD cell) produce

peptide hormone and serotonin

18

What increases surface area of the Intestines

= Length of small and large intestine
- Plicae circulares (valves of Kreckring)
- Villi
- Microvilli

19

What are the 3 levels of folding in the small intestine that increase surface area

- Plicae
- Crypt-Villus System
- Microvilli

20

These are folds of the mucosa, each with a submucosal core

Plicae

21

Each villus contains a core of

lamina propria

22

The crypts extend down between the _____ below the

Villi, below the bases of the villi

23

Crypts and villi constitute _______ of the small intestine

glands

24

Wall of villus is composed of ________ epithelium with _______

simple columnar epithelium with goblet cells

25

Each villus contains a blind-ending lymphatic referred to as a

lacteal

26

Each villus contains a ______ plexus

Capillary plexus

27

Each villus contains

-A core of lamina propria
- A capillary plexus
- a blind-ending lymphatic referred to as a lacteal

28

Microvilli are covered with ______ and _______

Glycoprotein and glycocalyx (glycolipid coat)

29

Glycocalyx (glycolipid coat of microvilli) contains an array of ________ enzymes . Name them? and who produces them

Brush-boarder enzymes
- Maltase
- Sucrase
- Isomaltase
- Lactase
- Lipase
- Peptidases

- Produced by small intestinal epithelial cells

30

Gastric glands are simple ______ ______ glands

Gastric glands are simple branched tubular glands

31

Bundles of actin filaments within microvillus are covered by a

formin cap

32

The actin filaments of a microvillus are tied to terminal web intermediate filaments (cytokeratins) via

spectrin fibrils

33

Microvilli are supported by

actin microfilaments

34

Actin filaments of microvilli are tied to ________ via spectrin fibrils

Terminal web intermediate filaments (cytokeratins)

35

Actin filaments of microvilli are bound to plasma membrane covering villus via membrane-linking proteins____ and ____

- Myosin I
- Calmodulin

36

Actin filaments of microvilli are bound to each other via actin cross-linking proteins _____ and _____

villin and fimbrin