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Cell Bio Block 3 > Integumentary system > Flashcards

Flashcards in Integumentary system Deck (41):
1

what are the 2 layers of the integumentary system?

epidermis
dermis

2

what type of epithelium is the epidermis and what is it derived from

stratified squamous epithelium (keratinized)
ectoderm

3

what type of epithelium is the dermis and what is it derived from?

dense connective tissue
mesoderm

4

what is the layer beneath the dermis?

hypodermis

5

what are the 5 layers of the epidermis?

Stratum basale
Stratum spinosum
Stratum granulosum
Stratum lucidum
Stratum corneum

6

how are cells of the stratum basale connected to the basal lamina?

hemidesmosomes

7

how are the cells of the stratum basale connected to each other?

desmosomes

8

what do the cells of the stratum basale contain?

melanin

9

what special process happens in the stratum basale because of the abundant o2 and nutrients?

mitosis

10

what special feature do the cells in the stratum spinosum have?

spines

11

how are the spines connected to adjacent cells?

desmosomes

12

what are the thickening of the desmosomes in the stratum spinosum called?

nodes of Bizzozero

13

what granules are in the cells of the stratum granulosum?

keratohyalin granules

14

what proteins/compounds are in the keratohyalin granules?

cysteine and histadine-rich proteins

15

what are cells of the stratum corneum filled w/?

keratin

16

what type of collagen makes up the papillary layer of the dermis?

type 1 and 3

17

what are dermal papillae?

protrusions into the epidermis= fingerprints

18

what type of collagen/fibers make up the reticular layer of the dermis?

type 1 collagen + elastic fibers

19

what do the type 1 collagen and elastic fibers of the reticular layer of the dermis form in the skin?

Langer's lines

20

what does excessive stretching of the reticular layer of the dermis cause?

stretch marks

21

where are two examples of smooth muscle in the hypodermis?

arrector pili muscle (cause goose bumps around hair)
dartos muscle in scrotum

22

what is the layer of adipose tissue of the hypodermis called?

panniculus adiposus

23

what is the vestigual layer of striated muscle deep to the subcutaneous fascia in the hypodermis?

panniculus carnosus

24

what 3 things do keratinocytes of the epidermis synthesize?

keratin
keratohyalin granules
lamellar bodies

25

what are melanocytes derived from?

neural crest cells

26

What is an epidermal-melanin unit?

Melanocyte+ a # of keratinocytes

27

what is the most significant factor in skin color?

melanin content

28

what enzyme is critical to produce melanin?

tyrosinase

29

what are the most common characteristics in Waardenburg syndrome?

Patch of white hair and skin
Heterochromia irides (eyes of different colors)
Deafness

30

what causes Waardenburg syndrome?

faulty proliferation/migration of neural crest cells

31

what are 3 key features of Langerhans cell?

Part of the mononuclear phagocytic system
APC
Initiates cutaneous hypersensitivity

32

what is Merkel’s corpuscle

Merkel’s corpuscle= neuron + Merkel cell

33

what are Pacinian corpuscles

Deep pressure receptors

34

what are Meissner’s corpuscles

Touch receptors (dermal papillae)

35

what are Ruffini corpuscles

Mechanical displacement of collagen fibers

36

How is the Sebaceous gland connected to the hair?

by the pilosebaceous duct

37

what is the type of secretion that is used to secrete sebum?

holocrine

38

what are eccrine sweat glands also called?

sudoriferous glands

39

how is the excretory product discharged from apocrine sweat glands?

exocytosis

40

what are the parts of the nail?

Root
Matrix
Lunula (white half moon)
Eponychium (cuticle)
Hyponychium (under the nail)

41

what is the name of the eyelash mite?

Demodex folliculorum