Integumentary system Flashcards

(41 cards)

1
Q

what are the 2 layers of the integumentary system?

A

epidermis

dermis

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2
Q

what type of epithelium is the epidermis and what is it derived from

A

stratified squamous epithelium (keratinized)

ectoderm

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3
Q

what type of epithelium is the dermis and what is it derived from?

A

dense connective tissue

mesoderm

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4
Q

what is the layer beneath the dermis?

A

hypodermis

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5
Q

what are the 5 layers of the epidermis?

A
Stratum basale
Stratum spinosum
Stratum granulosum
Stratum lucidum
Stratum corneum
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6
Q

how are cells of the stratum basale connected to the basal lamina?

A

hemidesmosomes

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7
Q

how are the cells of the stratum basale connected to each other?

A

desmosomes

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8
Q

what do the cells of the stratum basale contain?

A

melanin

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9
Q

what special process happens in the stratum basale because of the abundant o2 and nutrients?

A

mitosis

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10
Q

what special feature do the cells in the stratum spinosum have?

A

spines

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11
Q

how are the spines connected to adjacent cells?

A

desmosomes

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12
Q

what are the thickening of the desmosomes in the stratum spinosum called?

A

nodes of Bizzozero

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13
Q

what granules are in the cells of the stratum granulosum?

A

keratohyalin granules

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14
Q

what proteins/compounds are in the keratohyalin granules?

A

cysteine and histadine-rich proteins

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15
Q

what are cells of the stratum corneum filled w/?

A

keratin

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16
Q

what type of collagen makes up the papillary layer of the dermis?

A

type 1 and 3

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17
Q

what are dermal papillae?

A

protrusions into the epidermis= fingerprints

18
Q

what type of collagen/fibers make up the reticular layer of the dermis?

A

type 1 collagen + elastic fibers

19
Q

what do the type 1 collagen and elastic fibers of the reticular layer of the dermis form in the skin?

A

Langer’s lines

20
Q

what does excessive stretching of the reticular layer of the dermis cause?

A

stretch marks

21
Q

where are two examples of smooth muscle in the hypodermis?

A

arrector pili muscle (cause goose bumps around hair)

dartos muscle in scrotum

22
Q

what is the layer of adipose tissue of the hypodermis called?

A

panniculus adiposus

23
Q

what is the vestigual layer of striated muscle deep to the subcutaneous fascia in the hypodermis?

A

panniculus carnosus

24
Q

what 3 things do keratinocytes of the epidermis synthesize?

A

keratin
keratohyalin granules
lamellar bodies

25
what are melanocytes derived from?
neural crest cells
26
What is an epidermal-melanin unit?
Melanocyte+ a # of keratinocytes
27
what is the most significant factor in skin color?
melanin content
28
what enzyme is critical to produce melanin?
tyrosinase
29
what are the most common characteristics in Waardenburg syndrome?
Patch of white hair and skin Heterochromia irides (eyes of different colors) Deafness
30
what causes Waardenburg syndrome?
faulty proliferation/migration of neural crest cells
31
what are 3 key features of Langerhans cell?
Part of the mononuclear phagocytic system APC Initiates cutaneous hypersensitivity
32
what is Merkel’s corpuscle
Merkel’s corpuscle= neuron + Merkel cell
33
what are Pacinian corpuscles
Deep pressure receptors
34
what are Meissner’s corpuscles
Touch receptors (dermal papillae)
35
what are Ruffini corpuscles
Mechanical displacement of collagen fibers
36
How is the Sebaceous gland connected to the hair?
by the pilosebaceous duct
37
what is the type of secretion that is used to secrete sebum?
holocrine
38
what are eccrine sweat glands also called?
sudoriferous glands
39
how is the excretory product discharged from apocrine sweat glands?
exocytosis
40
what are the parts of the nail?
``` Root Matrix Lunula (white half moon) Eponychium (cuticle) Hyponychium (under the nail) ```
41
what is the name of the eyelash mite?
Demodex folliculorum