Intro to Antihypertensive Agents V Flashcards Preview

RENAL II Exam 3 > Intro to Antihypertensive Agents V > Flashcards

Flashcards in Intro to Antihypertensive Agents V Deck (50):
1

acebutolol

beta-blocker

2

atenolol

beta-blocker

3

betaxolol

beta-blocker

4

bisoprolol

beta-blocker

5

carteolol

beta-blocker

6

carvedilol

beta-blocker

7

esmolol

beta-blocker

8

labetolol

beta-blocker

9

metoprolol

beta-blocker

10

nadolol

beta-blocker

11

nebivolol

beta-blocker

12

penbutolol

beta-blocker

13

pindolol

beta-blocker

14

propranolol

beta-blocker

15

timolol

beta-blocker

16

doxazosin

alpha1 blocker

17

prazosin

alph1 blocker

18

terazosin

alpha1 blocker

19

clonidine

central acting sympatholytic

20

guanabenz

central acting sympatholytic

21

guanfacine

central acting sympatholytic

22

methyldopa

central acting sympatholytic

23

alpha1

vasculature

24

beta1

cardiac

25

catecholamine

from adrenal medulla
-affect tone of resistance in vessels as well as HR and output

26

beta1 selective blocker

metoprolol and atenolol

27

non-selective beta blocker

propanolol

28

ISA

intrinsic sympathomimmetic activity
-low sympathetic tone - agonist
-high sympathetic tone - antagonist

29

carvedilol and labetalol

alpha and beta blockers

30

nadolol

non-selective beta blocker
-contraindicated in asthma

31

beta2 bronchodilation

non-selective beta blockers
-relative contraindication

32

diabetes

don't want non-selective beta blocker

33

beta-blockers

no longer first line treatment for HTN

-except when with heart failure, recent MI, or reduced left ventr. function

34

labetalol

selective alpha 1 blocker
non-selective beta 1 and 2 blocker

partial agoninst at beta 2

-IV for severe HTN
-acceptable for HTN during pregnancy

35

carvedilol

non-selective beta-blocker and alpha-1 blocker

also antioxidant

36

nebivolol

beta1 selective blocker
-also decreases TPR and BP
-via increased nitric oxide formation

37

phenylephrine

alpha agonist
alpha 1 > alpha 2

38

beta blockers with vasodilator activity

non-selective - carteolol, carvedilol, labetalol

beta-1 selective - betaxolol, nebivolol

ex/ nebivolol - increases NO

39

esmolol

beta1 selective
-very rapid onset and short duration of action

IV for peri-op tachycardia and HTN, hypertensive emergencies, arrhythmias

also used in electroconvulsive therapy

aka brevibloc

40

prazosin

alpha-1 selective blocker
-no loss of alpha2 inhibition on NE release

admin of phenylephrine - no effect

41

phentolamine

non-selective alpha blocker
-decreased alpha 2 inhibitor
-therefore larger increase of NE release

42

men with HTN and BPH

alpha-1 selective blocker
-prazosin

43

clonidine receptor agonist

clonidine

44

clonidine

alpha 2 receptor agonist
-central acting

increased BP, then decreased BP**

sudden withdrawal - hypertensive crisis

45

dangerous effect on fetus

ACE (-)
-ends in pril

46

methyldopa

converted to methyl-NE
-stored in NE vesicles

central alpha2 agonist
-decreased sympathetic outflow
-decreased BP

-treat HTN in pregnancy***

aka aldomet

47

hypertensive emergency

involves organ damage

drugs given IV

48

renoprotective

ACE (-) or ARBs

49

no used unless specific indication

beta-blockers

50

african descent

ARB and ACE (-) worse