Flashcards in Intro to Antihypertensive Agents V Deck (50):
1
acebutolol
beta-blocker
2
atenolol
beta-blocker
3
betaxolol
beta-blocker
4
bisoprolol
beta-blocker
5
carteolol
beta-blocker
6
carvedilol
beta-blocker
7
esmolol
beta-blocker
8
labetolol
beta-blocker
9
metoprolol
beta-blocker
10
nadolol
beta-blocker
11
nebivolol
beta-blocker
12
penbutolol
beta-blocker
13
pindolol
beta-blocker
14
propranolol
beta-blocker
15
timolol
beta-blocker
16
doxazosin
alpha1 blocker
17
prazosin
alph1 blocker
18
terazosin
alpha1 blocker
19
clonidine
central acting sympatholytic
20
guanabenz
central acting sympatholytic
21
guanfacine
central acting sympatholytic
22
methyldopa
central acting sympatholytic
23
alpha1
vasculature
24
beta1
cardiac
25
catecholamine
from adrenal medulla
-affect tone of resistance in vessels as well as HR and output
26
beta1 selective blocker
metoprolol and atenolol
27
non-selective beta blocker
propanolol
28
ISA
intrinsic sympathomimmetic activity
-low sympathetic tone - agonist
-high sympathetic tone - antagonist
29
carvedilol and labetalol
alpha and beta blockers
30
nadolol
non-selective beta blocker
-contraindicated in asthma
31
beta2 bronchodilation
non-selective beta blockers
-relative contraindication
32
diabetes
don't want non-selective beta blocker
33
beta-blockers
no longer first line treatment for HTN
-except when with heart failure, recent MI, or reduced left ventr. function
34
labetalol
selective alpha 1 blocker
non-selective beta 1 and 2 blocker
partial agoninst at beta 2
-IV for severe HTN
-acceptable for HTN during pregnancy
35
carvedilol
non-selective beta-blocker and alpha-1 blocker
also antioxidant
36
nebivolol
beta1 selective blocker
-also decreases TPR and BP
-via increased nitric oxide formation
37
phenylephrine
alpha agonist
alpha 1 > alpha 2
38
beta blockers with vasodilator activity
non-selective - carteolol, carvedilol, labetalol
beta-1 selective - betaxolol, nebivolol
ex/ nebivolol - increases NO
39
esmolol
beta1 selective
-very rapid onset and short duration of action
IV for peri-op tachycardia and HTN, hypertensive emergencies, arrhythmias
also used in electroconvulsive therapy
aka brevibloc
40
prazosin
alpha-1 selective blocker
-no loss of alpha2 inhibition on NE release
admin of phenylephrine - no effect
41
phentolamine
non-selective alpha blocker
-decreased alpha 2 inhibitor
-therefore larger increase of NE release
42
men with HTN and BPH
alpha-1 selective blocker
-prazosin
43
clonidine receptor agonist
clonidine
44
clonidine
alpha 2 receptor agonist
-central acting
increased BP, then decreased BP**
sudden withdrawal - hypertensive crisis
45
dangerous effect on fetus
ACE (-)
-ends in pril
46
methyldopa
converted to methyl-NE
-stored in NE vesicles
central alpha2 agonist
-decreased sympathetic outflow
-decreased BP
-treat HTN in pregnancy***
aka aldomet
47
hypertensive emergency
involves organ damage
drugs given IV
48
renoprotective
ACE (-) or ARBs
49
no used unless specific indication
beta-blockers
50