Intro to Antihypertensive Agents V Flashcards
(50 cards)
1
Q
acebutolol
A
beta-blocker
2
Q
atenolol
A
beta-blocker
3
Q
betaxolol
A
beta-blocker
4
Q
bisoprolol
A
beta-blocker
5
Q
carteolol
A
beta-blocker
6
Q
carvedilol
A
beta-blocker
7
Q
esmolol
A
beta-blocker
8
Q
labetolol
A
beta-blocker
9
Q
metoprolol
A
beta-blocker
10
Q
nadolol
A
beta-blocker
11
Q
nebivolol
A
beta-blocker
12
Q
penbutolol
A
beta-blocker
13
Q
pindolol
A
beta-blocker
14
Q
propranolol
A
beta-blocker
15
Q
timolol
A
beta-blocker
16
Q
doxazosin
A
alpha1 blocker
17
Q
prazosin
A
alph1 blocker
18
Q
terazosin
A
alpha1 blocker
19
Q
clonidine
A
central acting sympatholytic
20
Q
guanabenz
A
central acting sympatholytic
21
Q
guanfacine
A
central acting sympatholytic
22
Q
methyldopa
A
central acting sympatholytic
23
Q
alpha1
A
vasculature
24
Q
beta1
A
cardiac
25
catecholamine
from adrenal medulla
| -affect tone of resistance in vessels as well as HR and output
26
beta1 selective blocker
metoprolol and atenolol
27
non-selective beta blocker
propanolol
28
ISA
intrinsic sympathomimmetic activity
- low sympathetic tone - agonist
- high sympathetic tone - antagonist
29
carvedilol and labetalol
alpha and beta blockers
30
nadolol
non-selective beta blocker
| -contraindicated in asthma
31
beta2 bronchodilation
non-selective beta blockers
| -relative contraindication
32
diabetes
don't want non-selective beta blocker
33
beta-blockers
no longer first line treatment for HTN
-except when with heart failure, recent MI, or reduced left ventr. function
34
labetalol
selective alpha 1 blocker
non-selective beta 1 and 2 blocker
partial agoninst at beta 2
- IV for severe HTN
- acceptable for HTN during pregnancy
35
carvedilol
non-selective beta-blocker and alpha-1 blocker
also antioxidant
36
nebivolol
beta1 selective blocker
- also decreases TPR and BP
- via increased nitric oxide formation
37
phenylephrine
alpha agonist
| alpha 1 > alpha 2
38
beta blockers with vasodilator activity
non-selective - carteolol, carvedilol, labetalol
beta-1 selective - betaxolol, nebivolol
ex/ nebivolol - increases NO
39
esmolol
beta1 selective
-very rapid onset and short duration of action
IV for peri-op tachycardia and HTN, hypertensive emergencies, arrhythmias
also used in electroconvulsive therapy
aka brevibloc
40
prazosin
alpha-1 selective blocker
-no loss of alpha2 inhibition on NE release
admin of phenylephrine - no effect
41
phentolamine
non-selective alpha blocker
- decreased alpha 2 inhibitor
- therefore larger increase of NE release
42
men with HTN and BPH
alpha-1 selective blocker
| -prazosin
43
clonidine receptor agonist
clonidine
44
clonidine
alpha 2 receptor agonist
-central acting
increased BP, then decreased BP**
sudden withdrawal - hypertensive crisis
45
dangerous effect on fetus
ACE (-)
| -ends in pril
46
methyldopa
converted to methyl-NE
-stored in NE vesicles
central alpha2 agonist
- decreased sympathetic outflow
- decreased BP
-treat HTN in pregnancy***
aka aldomet
47
hypertensive emergency
involves organ damage
drugs given IV
48
renoprotective
ACE (-) or ARBs
49
no used unless specific indication
beta-blockers
50
african descent
ARB and ACE (-) worse
