Introduction to genetics Flashcards

1
Q

G1 phase

A

Growth phase where a cell grows in size and prepares later for DNA replication

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2
Q

S-phase

A

DNA replication occurs

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3
Q

G2 phase

A

Cell preparing proteins like microtubules, needed for cell division during mitosis

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4
Q

M-phase

A

Mitosis

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5
Q

G0-phase

A

Some cells may remain in quiescent, non-dividing stage

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6
Q

Structure of DNA

A

double stranded helix

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7
Q

Nitrogenous Bases: 4 types

A

Adenine (A)
Thymine (T)
Guanine (G)
Cytosine (C)

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8
Q

Bases have specific pairing

A

A=T, C=G

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9
Q

Two strands run in opposite directions, one from ______ and the other from ________

A

5’ to 3’ , 3’ to 5’

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10
Q

DNA replication

A
  • Parent DNA molecule; two complementary strands of base-paired nucleotides
  • Parental strands unwind and separate at several points along the DNA molecule, forming replication forks
  • Each parental strand provides a template that attracts and binds complementary bases, A with T and G with C
  • Sugar-phosphate back-bone of daughter strands closed. Each new DNA molecule consists of one parental and one daughter strand, as a result of semiconservative replication.
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11
Q

Cell division

A

A process by which a cell (parent cell) , divide into two or more cells (daughter cells)

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12
Q

Mitosis (produces body cells)

A

generates 2 identical diploid daughter cells and are capable of dividing

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13
Q

Meiosis (produces sex cells)

A

Generates 4 haploid cells called gametes and cannot divide again until fertilization

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14
Q

Diploid

A

2N , actual number of chromosomes in a cell

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15
Q

Haploid

A

N, half the number of chromosomes in a sperm or egg cell

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16
Q

In humans one set of chromosomes

A

23 pairs / 46 chromosomes

17
Q

how many chromosomes in sperm/egg cell

A

23 chromosomes

18
Q

Mitosis + cytokinesis

A

mitotic phase/ M phase

19
Q

WHAT IS cytokinesis

A

division of nuclei, cytoplasm, organelles & cell membrane

Cytokinesis completion signals the end of the cell division

20
Q

The period of one mitosis to the next is referred to as

A

interphase

21
Q

4 stages of mitosis

A
  • Prophase
  • Metaphase
  • Anaphase
  • Telophase
22
Q

Prophase

A

DNA condenses into visible threads

Nuclear envelope disintegrates

23
Q

Metaphase

A

Chromosomes line up in the middle of the cell

24
Q

Anaphase

A

Chromosomes (sister chromatids) separate in opposite directions

25
Telophase
Chromosomes restored to less compact, non-mitotic state Nuclear envelope form around daughter nuclei
26
Error in Mitosis
- Error in cell mitosis will activate programmed cell death ( apotosis ) , which will kill the cell - Can lead to cancer or tumour formation
27
meiosis essential
for sexual reproduction
28
Meiosis occurs in 2 stages
Meiosis 1, meiosis 11
29
Meiosis 1
Homologous pairs in a diploid cell separate producing two haploid cells (23 chromosomes)
30
Meiosis 11
By the end of Meiosis 1, sister chromatids are finally split, creating 2 haploid cells per daughter cell (23 chromosomes)
31
End product of meiosis is
4 haploid cells from two haploid cells