Iron Deficiency Flashcards
0
Q
What is the aetiology of anaemia?
A
Decreased proliferation of RBC
Impaired maturation of RBC
Loss of blood
1
Q
What is anaemia?
A
Lowering of haemoglobin levels
2
Q
What are the stages of erythrocyte development?
A
Stem cell Early erythroblast Intermediate erythroblast Late erythroblast Reticulocyte Mature red blood cell
3
Q
What are characteristics of erythrocytes?
A
Biconcave disk
120 day lifespan
No organelles
4
Q
What is the function of haemoglobin?
A
Carry gases around the body
Can bind to multiple gases
Can form carboxyl haem
5
Q
Where does a red blood cells energy come from?
A
Embden-Meyerhof Glycolyic Pathway
6
Q
What is microcytic hypochromic anaemia?
A
Nutritional deficiency of iron
Iron overload
7
Q
Why is unbound iron toxic?
A
It causes free radical formation
8
Q
Where is iron absorbed into the body?
A
Duodenum
9
Q
What molecule does iron bind to be transferred to erythrocytes?
A
Transferrin
