Inflammatory Response Flashcards

0
Q

What are the cells of the non specific response?

A

Phagocytic cells

Non phagocytic cells

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1
Q

What are the 4 non specific innate defenses?

A

Structural barriers
White blood cells
Antimicrobial proteins
Inflammatory response

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2
Q

What characterises the non specific response?

A

Innate
Against anything foreign
Always the same

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3
Q

What are two examples of non specific response?

A

Inflammatory response

Acute phase response

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4
Q

What are the signs of acute inflammation?

A

Redness
Heat
Swelling
Pain

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5
Q

What does acute inflammation involve?

A

Dilation of small blood vessels
Increased blood flow
Increased permeability
Cell recruitment and migration

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6
Q

What are the mediators of the immune response?

A

Vasoactive amines
Arachidonic acid metabolites
Complement and other systems
Cytokines

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7
Q

What is the complement system?

A

A series of proteins in plasma

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8
Q

How can the complement system be activated?

A

Classical pathway

Alternate pathway

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9
Q

What are the products of the complement system?

A

Opsonins
Anaphylatoxins
Chemotactic factors
Attack complexes

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10
Q

What are the functions of cytokines?

A

Chemo taxis

Cellular proliferation

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11
Q

What are the stages of cell recruitment?

A
Margination
Adhesion
Migration
Chemotaxis
Phagocytosis
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12
Q

What is the acute phase response?

A

A whole body response to infection

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13
Q

What does the acute phase response cause?

A

Increased number of neutrophils

greater production of acute phase proteins

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14
Q

What is an immunogen?

A

Stimulates a specific immune response

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15
Q

What is an antigen?

A

Combines with the products of an immune response

16
Q

What is a epitope?

A

The part of the immunogen recognised by a small lymphocyte to which an antibody binds

17
Q

What happens when a small lymphocyte binds to the epitope?

A

The cell undergoes clonal expansion

18
Q

What are the two types of small lymphocytes?

A

B and T lymphocytes