Flashcards in IUGR Deck (32):
Causes of baby being small? Placental?
4 congenital disease
UPD uni parental disomy dangerous why?
Because will get all autosomal recessive disorders
Maternal restraint of growth?
Prevent too big a baby in uterus
If have UPD both from mom? Dad?
Double growth genes from mother = big baby
Dad: both growth genes off = small Abby
How to get UPD?
trisomy and loses drops one
Confined placental mosaicism?
Placenta has trisomy, fetus doesn't
important Structural defect
two infections that cause IUGR?
Where to get CMV?
What kind of CMV virus is virus?
How to prevent CMV?
Where do you get toxo?
Stray cats - pooing in garden and your gardening/sandbox.
Toxoplasmosis is What species?
DM - atherosclerosis
Acquired: anti phospholipid
-Rest, sx, cancer
6 hereditary thrombophilias?
Protein S, C
High altitude (lower O2)
Common reason for placenta abrupt ion?
Hemorrhagic infarct (99%)
Screening for IUGR
Optimal single biometric measure?
-Work and rest optimization
-NOT vitamin E or C
Mx of IUGR?
Look for cause
How to confirm genetically small?
Absence of risk factors
Normal growth trajectory
Bio physically active
Normal amniotic fluid
Normal umbilical and other Dopller studies
How to investigate IUGR
Karyotyping NIPS, why do it at 35weeks?
-Won't compromise future reproduction, prevent unnecessary C-section if baby was destined to die anyways.
-prepare the paediatricians
-termination in late preg
Can you terminate pregnancy?
Need 2 doctors, not reason
Viability of baby after how many weeks?
Why terminate late?
-If prognosis is not known until late preg (eg. CMV)
Rx of IUGR?
Can't use aspirin - too late
Control DM better
TPN will work - hyperalimentation but will die: grow too big for placenta (O2)
Yes, will grow, but will outgrow O2 placenta supply and die. Not use.