Knowmedge Internal Medicine ABIM Exam Review Questions - General Internal Medicine

Question 0

What is the fundoscopic exam finding often seen with idiopathic intracranial hypertension (Pseudotumor cerebri)?

Answer 0

Papilledema

Question 1

What vitamin deficiency can occur with use of Isoniazid (INH)?

Answer 1

Vitamin B6 (Pyridoxine)

Question 2

What is the ideal LDL goal in CAD patients or CAD equvialent patients?

Answer 2

Less than 70 mg/dl

Question 3

What is the inheritance pattern for Hereditary Hemorrhagic Telangiectasia (HHT)?

Answer 3

Autosomal dominant. HHT is also known as Osler-Weber-Randau syndrome

Question 4

What is the most common symptom of Hereditary Hemorrhagic Telangiectasia (HHT)?

Answer 4

Epistaxis (nose bleeding)

Question 5

What are the possible agents for treating hypertension in pregnant women?

Answer 5

Hydralazine, Labetalol, Alpha methyldopa

Question 6

Which pain medication should be avoided in patients who are taking SSRIs for depression?

Answer 6

Tramadol (concurrent use of SSRI with tramadol can cause serotonin syndrome)

Question 7

On fundoscopic examination, which condition is associated with cherry red spots of the macula?

Answer 7

Retinal artery occlusion

Question 8

Which disease is associated with decreased uroporphyringoen decarboxylase activity?

Answer 8

Porphyria cutanea tarda

Question 9

Best next step after pt has tried NSAIDs / OCPs for primary dymenorrhea but symptoms persist >3 months?

Answer 9

Ultrasound to rule out uterine abnormalities like fibroids

Question 10

What is the anti-depressant category of choice in patients with bulemia?

Answer 10

SSRIs

Question 11

What is the main anti-depressant to be avoided in patients with seizure disorder?

Answer 11

Buproprion

Question 12

Anaphlyaxis reaction is an example of which type of hypersensitivity reaction?

Answer 12

Type 1 hypersensitivity reaction

Question 13

Which class of anti-depressants are associated with widened QRS complex that can be treated with bicarbonate?

Answer 13

Tricyclic antidepressants (TCAs)

Question 14

Which statin is the drug of choice in HIV patients?

Answer 14

Pravastatin

Question 15

Within what age range does USPSTF recommend one-time screening for AAA in men with a smoking history?

Answer 15

65 to 75 years

Question 16

Name the supplement: Sleep aid also used for stress/anxiety relief. If combined with EtOH, can oversedate.

Answer 16

Kava

Question 17

Name the supplement: Used for benign prostatic hyperplasia. Can cause headaches and/or abdominal pain/nausea.

Answer 17

Saw Palmetto

Question 18

Name the supplement: Used against the common cold. Can cause nausea, rash and itchiness.

Answer 18

Echinacea

Question 19

Name the supplement: Used as an anti-depressant. Can potentially induces cytochrome P450 drug metabolism.

Answer 19

St. John’s Wort

Question 20

Name the supplement: Used against dementia. Can increase the risk of bleeding.

Answer 20

Ginkgo Biloba

Question 21

Long-term use of which potent antibiotic requires performing regular eye exams?

Answer 21

Linezolid

Question 22

What is the treatment of choice of dermatitis herpetiformis?

Answer 22

Dapsone

Question 23

What class of anti-depressants can be used for patients who are suffering from urge incontinence?

Answer 23

TCAs (Tricyclic anti-depressants)

Question 24

What is the enzyme that converts testosterone to estradiol?

Answer 24

Aromatase

Question 25

In hemochromatosis, which condition, if developed, is irreversible?

Answer 25

Hypogonadism which can lead to infertility

Question 26

Which gene test should be checked before administering azaithioprine to prevent dangerous bone marrow suppression?

Answer 26

TPMT gene test (thiopurine S-methyltransferase)

Question 27

What is the laboratory screening test for chronic alcohol abuse?

Answer 27

Carbohydrate free transferrin level elevated

Question 28

What blood test is the initial screening test for suspected systemic mastocytosis?

Answer 28

Serum tryptase level

Question 29

Strong family history of premature heart disease + patient has a low HDL. What level is likely to be elevated?

Answer 29

Lipoprotein a or Lp(a)

Question 30

What vitamin or mineral deficiency is associated with rash and alopecia in patients on TPN feeding?

Answer 30

Zinc deficiency