Step 1 Buzzwords Anatomy Flashcards

USMLE Step 1 Recall: Buzzwords for the Boards Second Edition (687 cards)

0
Q

Is an Afferent or Efferent pupillary defect described as B/L pupillary constriction when light is shined in the Unaffected eye and B/L paradoxical dilation when light is shined in the Affected eye?

A

Afferent pupillary defect (CN II lesion); in an Efferent pupillary defect (CN III), B/L Constrict when light is shined in the unaffected eye and consentual pupil constriction occurs when light is shined in the affected eye.

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1
Q

GROSS ANATOMY

What gland is found in the muscular triangle of the neck?

A

Thyroid gland

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2
Q

What is the name of the spinal cord passing within the subarachnoid space and forming the spinal nerves that exit the lumbar and sacral foramina?

A

Cauda equinia

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3
Q

Name the laryngeal muscle described by the following:

Pulls the arytenoids cartilages closer to the thyroid, relaxing the vocal ligaments and thereby decreasing the pitch?

A

Thyroarytenoid muscles

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4
Q

Tenses the vocal ligaments, increasing the distance between the cartilages, thereby increasing the pitch?

A

Cricothyroid muscles

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5
Q

Adducts the vocal ligaments, closes the air passageway during swallowing, and allows phonation?

A

Lateral cricoarytenoid muscles

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6
Q

Only muscle to abduct the vocal cords?

A

Posterior cricoarytenoid muscles

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7
Q

Where does the parotid (Stensen’s) duct enter the oral cavity?

A

Opposite the second upper molar tooth

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8
Q

From what aortic arch are the following structures derived?

Common and internal carotid arteries

A

Third aortic arch

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9
Q

Degenerates

A

Fifth

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10
Q

Stapes artery

A

Second

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11
Q

Maxillary artery

A

First

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12
Q

Arch of the aorta and right subclavian artery

A

Fourth

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13
Q

Right and left pulmonary arteries and the ductus arteriosus

A

Sixth. MS CARD is the mnemonic for the aortic arch derivatives. M, Maxillary; S, Stapes; C, Common and internal carotid; A, Arch of the aorta and right subclavian; R, Right and left pulmonary arteries and the ductus arteriosus; D, Degenerates.

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14
Q

What abdominal muscle contributes to the anterior layer of the rectus sheath, forms the inguinal ligament, and in men gives rise to the external spermatic fascia of the spermatic cord?

A

External abdominal oblique

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15
Q

Name the compartment of the lower extremity and the nerve based on its movements.
Adduct the thigh and flex the hip

A

Medial compartment of the thigh, obturator nerve

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16
Q

Plantar flex the foot, flex the toes, and invert the foot

A

Posterior compartment of the leg, common peroneal nerve

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17
Q

Dorsiflex the foot, extend the toes, and invert the foot

A

Anterior compartment of the leg, deep peroneal nerve

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18
Q

Flex the hip and extend the knee

A

Anterior compartment of the thigh, tibial nerve

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19
Q

Extend the hip and flex the knee

A

Posterior compartment of the thigh, tibial nerve

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20
Q

Plantar flex the foot and evert the foot

A

Lateral compartment of the leg, superficial peroneal nerve

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21
Q

What are the five branches of the posterior cord of the brachial plexus?

A

STARS

  1. upper Subscapularis
  2. Thoracodorsal
  3. Axillary
  4. Radial
  5. lower Subscapularis
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22
Q

Name the correct artery.

The right recurrent laryngeal nerve passes around it.

A

Right brachiocephalic artery

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23
Q

The left recurrent laryngeal nerve passes around it.

A

Arch of the aorta

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24
The inferior mesenteric artery drains into it.
The splenic vein
25
Are the quadrate and caudate lobs of the liver functionally part of the left or right lobe?
Functionally they are part of the Left lobe of the liver because they receive their blood supply from the left hepatic artery. Anatomically they are considered part of the Right lobe of the liver.
26
What bones make up the acetabulum?
Pubis, ilium, and ischium
27
What is the anatomic positioning of the right and left gastric nerve plexus of the esophagus as they pass through the diaphragm?
LARP: Left goes Anterior and Right goes Posterior (because of the rotation of the gut; remember your embryology!)
28
What vessel is lacerated in an epidural hematoma?
Middle meningeal artery
29
True or false? Below the arcuate line, all the aponeurotic fibers run anterior to the rectus abdominis.
True
30
What ocular muscle | Adducts the eyeball and is involved in horizontal conjugate gaze?
Medial rectus (CN III)
31
Elevates and adducts the eyeball?
Superior rectus (CN III)
32
Depresses and abducts the eyeball?
Superior Oblique (CN IV)
33
Elevates and abducts the eyeball?
Inferior Oblique (CN III)
34
Abducts the eyeball and is involved in horizontal conjugate gaze?
Lateral rectus (CN VI)
35
Depresses and adducts the eyeball?
``` Inferior rectus (CN III) "LR6 SO4 R3" (CN VI, Lateral Rectus. CN IV, Superior Oblique. CN III innervates the Rest.) ```
36
Which muscles of the eye are under parasympathetic control?
Constrictor pupillae and ciliary muscles
37
Which direction does the uvula deviate in a left vagus nerve lesion?
A Left CN X lesion results in the uvula deviating to the Right. (Uvula points Away from the affected side.)
38
Is a subdural hematoma an arterial or venous bleed?
Subdural hematoma is a rupture of the cerebral Veins where they enter the superior sagittal sinus.
39
Which CNs are found in the midline of the brainstem?
CN I, II, III, VI, and XII | Add 1 + 1 = 2, 1 + 2 = 3, 1 + 2 + 3 = 6, 1 + 2 + 3 + 6 = 12
40
What muscles insert in or on the intertubercular groove of the humerus?
"Lady between two Majors": latissimus dorsi, pectoralis major, and teres major
41
What nerve supplies taste sensation to the anterior two-thirds of the tongue?
Chorda tympani of CN VII
42
What part of the heart forms | The right border?
Right atrium
43
Left border?
Left ventricle and auricle of left atrium
44
Apex?
Tip of the left ventricle
45
Base?
Left atrium and tip of the right atrium
46
Superior border?
Conus arteriosus of the right ventricle and right and left auricles
47
Anterior wall?
Right ventricle
48
Posterior wall?
Left atrium
49
Diaphragmatic wall?
Left ventricle and tip of right ventricle
50
What nerves carry the sensory and motor components of the blink reflex?
CN V1 carries the Sensory and CN VII carries the Motor component of the blink reflex.
51
What muscle keeps the stapes taut against the oval window?
Stapedius muscle
52
Name of the components of the femoral canal, working laterally to medially.
NAVEL: femoral Nerve, Artery, Vein, Empty space, and Lymphatics/Lacunar ligament
53
What muscle is most superior in the orbit?
Levator palpebrae superioris
54
What portion of the pericardium adheres to the tunica adventitia of the great vessels?
Fibrous pericardium
55
What two veins form the portal vein?
The superior mesenteric vein and the splenic vein (after it receives the inferior mesenteric vein) join to form the portal vein.
56
What CNs are responsible for the sensor and motor components of the light reflex?
CN II is the Sensory limb and CN III is the Motor component through parasympathetic stimulation.
57
During a lumbar puncture the needle passes through the interlaminar space in the midline of L3-L4, with the tip of the iliac crest in the flexed position as the landmark.
Order of puncture: 1, Skin. 2, Superficial fasica. 3, Deep fascia. 4, Supraspinous ligament. 5, Interspinous ligament. 6, Interlaminar space. 7, Epidural space. 8, Dura mater. 9, Arachnoid mater. 10, Subarachnoid space.
58
What ocular ganglion is affected if the pupil on the affected side sluggishly responds to light with normal accomodation?
Ciliary ganglion producing a tonic pupil
59
What is the name for the most prominent spinous process?
Vertebra prominens (C7 in 70% of cases, C6 in 20%, T1 in 10%)
60
What muscles make up the rotator cuff?
SITS - Subscapularis, Infraspinatus, Teres minor, Supraspinatus
61
What is the function of white rami communicantes?
They are preganglionic sympathetic axons. They are white because they are myelinated.
62
What muscle or muscles are innervated by the following nerves? Suprascapular nerve
Supraspinatus and infraspinatus
63
Upper subscapularis nerve
Subscapularis
64
Thoracodorsal nerve
Latissimus dorsi
65
Long thoracic nerve
Serratus anterior
66
What nerve is associated with the following functions? Flex the wrist and digits, pronate the wrist and the LOAF (Lumbricales, Opponens pollicis, Abductor pollicis brevis, Flexor pollicis brevis) muscles of the hand
Median nerve
67
Flex the shoulder, flex the elbow, and supinate the elbow
Musculocutaneous nerve
68
Innervation of the flexor carpi ulnaris, flexor digiti profundus (pinky and ring fingers), and the intrinsic muscles of the hand
Ulnar nerve
69
Supinate the wrist, extend the wrist and digits, extend the shoulder and elbow
Radial nerve
70
What abdominal muscle runs horizontally, contributes to the posterior rectus sheath, and contributes to form the conjoint tendon?
Transverse abdominis
71
Which CNs act as the sensory and motor components of the gag reflex?
The Sensory limb is via CN IX, and the Motor limb is from CN X.
72
Which kidney is lower? Why?
The right kidney is lower in the abdominal cavity because of the amount of space the liver occupies.
73
What two regions of the vertebral column are considered primary curvatures?
Thoracic and sacral
74
What vein drains the lower third of the thoracic wall?
Hemiazygous vein
75
At what point does the axillary artery become the brachial artery?
When it crosses the teres major
76
What direction would the tongue protrude in a left CN XII lesion?
Left CN XII lesion would result in the tongue pointing to the Left (points At the affected side).
77
At what vertebral level does the common carotid artery bifurcate?
C4 (the upper border of the thyroid cartilage)
78
True or false? Males are more likely to develop femoral hernias than females.
False. Females are more likely to develop femoral hernias than males (remember Female's Femoral).
79
In what compartment of the thigh is the profundus femoris artery found?
Anterior compartment (it's the blood supply to the posterior compartment)
80
Where is the cupola of the lung in relation to the subclavian artery and vein?
The cupola of the lung is Posterior to the subclavian artery and vein. It is the reason one must be cautious when performing subclavian venipuncture.
81
Trur or false? The first cervical vertebra has no vertebral body.
True. The odontoid process of C2 acts as the vertebral body of C1 allowing Lateral Rotation of the head.
82
What is the largest muscle in the body?
Gluteus maximus
83
At what vertebral levels does the Aortic Arch begin and end?
It both begins and ends at T4 (sternal angle [of Louis]).
84
What artery travels with the following veins? | Great cardiac vein
Left anterior descending artery
85
Middle cardiac vein
Posterior interventricular artery
86
Small cardiac vein
Right coronary artery
87
The ophthalmic artery is a branch of what vessel?
Internal carotid artery
88
What structure or structures cross the diaphragm at | T8 level?
IVC
89
T10 level?
Esophagus and esophageal nerve plexus (CN X)
90
T12 level?
Aorta, azygos vein, and thoracic duct. (Remember: 1 at T8, 2 at T10, and 3 at T12.)
91
Is the carotid sinus sensitive to pressure or oxygen?
The carotid sinus is a pressure-sensitive (low) receptor, while the carotid body is an oxygen-sensitive (low) receptor. (Remember "Sinus Pressure")
92
What nerve or nerves supply general sensation and taste to the posterior third of the tongue?
CN XI and X
93
Which muscle of the eye is under sympathetic control?
Dilator pulillae muscle
94
True or false? both the left and right lungs have an oblique fissure?
True. on the Right lung the Oblique Fissure divides the middle from the inferior lobe and the Horizontal Fissure further divides the middle from the upper lobe. On the Left the Oblique divides the superior from the inferior lobe.
95
What are the three branches of the lateral cord of the brachial plexus?
1. Lateral pectoral 2. Lateral head of the median 3. Musculocutaneous
96
What is the major difference between the veins in the face and the veins in the rest of the body?
There are no valves and no smooth muscle in the walls of the veins in the face.
97
Name the bony articulations of the following sites. Be specific. Shoulder
Clavicle, acromion, and glenoid fossa of the scapula and the humerus
98
Elbow
Humerus with ulna (major) and radius (minor)
99
Wrist
Radius with scaphoid and lunate and ulna with triquertrum and pisiform (Remember, for major articulations, wrist/radius and humerus/ulna = elbow)
100
What is the only laryngeal muscle innervated by the external laryngeal nerve?
Cricothyroid muscle; all other laryngeal muscles are innervated by the recurrent laryngeal nerve.
101
What seven structures are found in more than one mediastinum?
Esophagus, SVC, vagus nerve, azygos vein, thoracic duct, thymus, and phrenic nerve
102
How many bronchopulmonary segments are on the right lung? Left lung?
There are 10 bronchopulmonary segments on the Right and 8 on the Left.
103
The duodenal-jejunal flexure is suspended from the posterior abdominal wall by what?
Ligament of Treitz
104
What is the only tongue muscle innervated by CN X?
Palatoglossus muscle is innervated by CN X; all other tongue muscles are innervated by CN XII.
105
What abdominal muscle runs in a posteroinferior direction, splits to contribute to the rectus sheath, contributes to the formation of the conjoint tendon, and in men gives rise to the middle spermatic fascia and the cremasteric muscle of the spermatic cord?
Internal abdominal oblique
106
What are the five branches of the superior mesenteric artery?
Inferior pancreaticoduodenal, middle colic, right colic, ileocolic, and 10 to 15 intestinal arteries
107
What spinal nerves contribute to the pelvic splanchnic (parasympathetic) nerves that innervate the detrusor muscle of the urinary bladder?
S2, S3, S4 - keeps the pee-pee off the floor!
108
What connects the third and the fourth ventricles?
Cerebral aqueduct
109
What nerve and artery could be affected in a humeral neck fracture?
Axillary nerve and posterior humeral artery
110
What type of hernia is described as passing through the deep lateral ring of the inguinal canal?
Indirect hernia passes In the inguinal canal; a Direct hernia passes Directly through Hesselbach's triangle.
111
What two vessels come together to form the external jugular vein?
1. Posterior auricular vein | 2. Posterior division of the retromandibular vein
112
What is the only vein in the body with a high O2 content?
The pulmonary vein, which carries oxygenated blood from the lung to the left atrium.
113
What are the three branches of the celiac trunk?
The left gastric, splenic, and common hepatic arteries
114
What region of the pharynx does the eustachian tube enter?
Nasopharynx
115
What is the only muscle of the soft palate that is innervated by CN V3?
The tensor veli palatine is innervated by the mandibular division of the trigeminal nerve; all others are innervated by CN X.
116
How many pairs of spinal nerves exit from the spinal cord?
31 pairs
117
What artery turns into the dorsalis pedis when it crosses the extensor retinaculum?
Anterior tibial artery
118
What is the term for pupils that react Normally to Accomodation but have bilateral loss of constriction in response to Light?
Argyll Robertson pupils
119
What connects the lateral ventricles to the third ventricle?
Foramen of Monro
120
What nerve supplies General sensation to the anterior two-thirds of the tongue?
Lingual nerve of CN V3
121
What type of pleura is adherent to the surface of the organ?
Visceral pleura
122
What artery supplies the left ventricle, left atrium, and interventricular septum?
Left coronary artery
123
Where are the tonsillar tissues?
Waldeyer's ring
124
What is the name of the superficial Subcutaneous fascia of the abdomen containing Fat?
Camper's fascia; Scarpa's fascia is devoid of fat. (Remember campers are Fat.)
125
What are the three anatomic characteristics that differentiate the large bowel from the small bowel and the rectum?
1. Tinea coli 2. Haustra 3. Epiploic appendages
126
What area of the posterior aspect of the eye has no photoreceptors?
The optic disk is the blind spot.
127
At the level of rib 6, the internal thoracic artery divided into what two arteries?
Musculophrenic and superior epigastric arteries
128
What is the name of inflammation of the prepatellar bursa?
Housemaid's knee
129
What nerve roots constitute the cervical plexus?
C1 through C4
130
Name the compartment of the mediastinum associated with the following thoracic structure: Heart and pericardium
Middle
131
Descending aorta
Posterior
132
Thymus
Superior and anterior
133
Phrenic nerve
Superior and middle
134
Esophagus
Superior and posterior
135
Trachea
Superior
136
Ascending aorta
Middle
137
Thoracic duct
Superior and posterior
138
Azygos vein
Superior and posterior
139
SVC
Superior and middle
140
Splanchnic nerves
Posterior
141
Aortic arch
Superior
142
IVC
Middle
143
Vagus nerve
Posterior
144
Branchiocephalic vein
Superior
145
Pulmonary artery and veins
Middle
146
Left common carotid artery
Superior
147
Left subclavian artery
Superior
148
What is the only organ in the body supplied by preganglionic sympathetic fibers?
Adrenal medulla
149
The Left subclavian artery is a branch of what artery?
The Left is a branch of the Aortic arch, while the Right is a branch of the Branchioecephalic trunk.
150
What are the four muscles of mastication?
1. Masseter 2. Temporalis 3. Medial pterygoid 4. Lateral pterygoid
151
With what thoracic vertebra or vertebrae does rib 7 articulate?
Rib 7 articulates with T7 and T8. Each rib articulates with the corresponding numerical vertebral body and the vertebral body Below it.
152
What are the three branches of the inferior mesenteric artery?
Left colic, superior rectal, and sigmoidal arteries
153
What is the only valve in the heart with two cusps?
Mitral (bicuspid) valve
154
What are five clinical signs of portal HTN?
Caput medusa, internal hemorrhoids, esophageal varices, retroperitoneal varices, and splenomegaly
155
What three muscles constitue the erector spinae?
1. Iliocostalis 2. Longissimus 3. Spinalis ("I Love Science" muscles)
156
What nerve is compromised in carpal tunnel syndrome?
Median nerve
157
What vascular injury may result from a supracondylar fracture of the femur?
The popliteal artery, the deepest structure in the popliteal fossa, risks injury in a supracondylar fracture of the femur.
158
What nerve and artery could be affected in a Midshaft Humeral fracture?
Radial nerve and the profunda brachii artery
159
Name the 10 retroperitoneal organs.
1. Duodenum (all but the first part) 2. ascending Colon 3. Ureters 4. Pancreas 5. Supra renal glands (adrenals) 6. Descending colon 7. Aorta 8. Kidneys 9. Rectum 10. IVC. D CUPS DAKRI is the mnemonic, everything else is covered with peritoneum
160
Ventral rami of what cervical nerves constitute the phrenic nerve?
C3, C4, and C5 keep the diaphragm alive!
161
What is the region of the fallopian tube where fertilization most commonly occurs?
Ampulla
162
What foramen must be traversed for entry into the lesser peritoneal sac?
Foramen of Winslow
163
Name the structure that enters or exits the following foramina: Foramen magnum
CN XI, vertebral arteries
164
Foramen spinosum
Middle meningeal artery
165
Foramen rotundum
CN V2
166
Foramen ovale
CN V3 and the lesser petrosal nerve
167
Jugular foramen
CN IX, X, and XI; sigmoid sinus
168
Carotid canal
Internal carotid artery and sympathetic plexus
169
Stylomastoid foramen
CN VII
170
Hypoglossal canal
CN XII
171
Internal auditory meatus
CN VII and VIII
172
Optic canal
CN II and ophthalmic artery
173
Cribriform plate
CN I
174
What vessel can be found atop the scalene anterior?
Subclavian vein
175
What component of the corneal reflex is lost in a CN VII deficit?
Motor aspect
176
A motor lesion to the Right CN V results in deviation of the jaw to which side?
A Right CN V lesion results in weakened muscles of mastication, and the jaw deviates to the Right.
177
What two arteries join to form the superficial and deep palmar arches of the hand?
Ulnar and radial arteries (ulnar is the main supplier)
178
What two ligaments of the uterus are remnants of the gubernaculum?
Round and ovarian ligaments
179
What segments of the lumbosacral plexus form the following nerves? Tibial nerve
L4 to S3
180
Common peroneal nerve
L4 to S3
181
Femoral nerve
L2 to L4
182
Obturator nerve
L2 to L4 | L2 to L4, thigh; L4 to S3, leg
183
What three structures are in contact with the left colic flexure? With the right colic flexure?
Left: stomach, spleen, and left kidney; Right: liver, duodenum, and right kidney
184
What three muscles constitute the pes anserinus?
1. Sartorius 2. Gracilis 3. Semitendinous
185
What is the only Pharyngeal muscle Not innervated by CN X?
Stylopharyngeus muscle is innervated by CN IX; all other pharyngeal muscles are innervated by CN X.
186
What vessels carry Deoxygenated blood into the lungs from the right ventricle?
The right and left pulmonary Arteries, the only arteries that carry deoxygenated blood
187
Fracture of the fibular neck, resulting in foot drop, is an injury of what nerve?
Common peroneal nerve
188
What vein is formed by the union of the right and left brachiocephalic veins?
Superior vena cava
189
If inserting a needle to perform a pleural tap or insertion of a chest tube, do you use the inferior or the superior border of a rib as your landmark? Why?
The Superior border of the inferior intercostal rib is your landmark for a pleural tap because along the inferior border of each rib is the Neurovascular bundle, and you would risk injury if you went below the rib.
190
What muscle laterally rotates the femur to unlock the knee?
Popliteus
191
What chamber of the eye lies between the iris and the lens?
Posterior chamber
192
What artery supplies the right atrium, right ventricle, sinoatrial and atrioventricular nodes?
Right coronary artery
193
What four branches of the brachial plexus arise prior to the first rib?
1. Dorsal scapular 2. Suprascapular 3. Long thoracic 4. Nerve to subclavius
194
What vertebral level is makred by the xiphoid process?
T9
195
What lower extremity nerve is described by the following motor loss? Loss of eversion, inversion, dorsiflexion, and plantarflexion of the foot
Common peroneal nerve
196
Loss of flexion of the knees and toes, plantarflexion, and weakened inversion
Tibial nerve
197
Loss of knee extension, weakened hip flexion
Femoral nerve
198
Loss of abduction of the hip resulting in Trendelenburg gait
Superior gluteal nerve
199
Loss of flexion of the knee and all function below the knee, weakened extension of the thigh
Sciatic nerve
200
Loss of adduction of the thigh
Obturator nerve
201
What nerve lesion presents with ape or simian hand as its sign?
Median nerve lesion
202
What muscle acts in all ranges of motion of the arm?
Deltoid
203
What is the first branch of the abdominal artery?
Inferior phrenic artery
204
What vessel does the Right gonadal vein drain into?
The Right gonadal vein drains into the Inferior vena cava directly, and the Left gonadal vein drains into the Left renal vein.
205
What two muscles do you test to see whether CN XI is intact?
Trapezius and sternocleidomastoid
206
What two CNs are responsible for the carotid body and sinus reflexes?
CN IX and X
207
At what vertebral level does the trachea bifurcate?
T4 vertebral level posteriorly and anteiorly at the sternal angle (angle of Louis).
208
What is the function of the arachnoid granulations?
Resorb CSF into the blood
209
Damage to what nerve will give you winged scapula?
Long thoracic nerve. To avoid confusing Long thoracic nerve and Lateral thoracic artery: long has N for nerve; lateral has an A for artery.
210
What portion of the intervertebral disk is a remnant of the notochord?
Nucleus pulposus
211
What component of the pelvic diaphragm forms the rectal sling (muscle of continence)?
Puborectalis
212
What are the five branches of the median cord of the brachial plexus?
Four Ms and a U 1. Median 2. Medial antebrachial 3. Medial pectoral 4. Medial brachial cutaneus 5. Ulnar
213
What bone houses the ulnar groove?
Humerus (between the medial epicondyle and the trochlea)
214
What CN is associated with the sensory innervation of | Nasopharynx?
Maxillary division of CN V and glossopharyngeal nerves
215
Oropharynx?
Glossopharyngeal nerve
216
Laryngopharynx?
Vagus nerve
217
What protective covering adheres to the spinal cord and CNS tissue?
Pia mater
218
What is the name of the urinary bladder where the ureters enter and the urethra exits?
Urinary trigone
219
What is the term when the brachial artery is compressed, resulting in Ischemic contracture of the hand?
Volkmann's contracture
220
What attaches the cusps of the valves to the papillary muscles in the heart?
Chordae tendineae
221
What is the lymphatic drainage of the pelvic organs?
Internal iliac nodes
222
What bursa is inflamed in clergyman's knee?
Infrapatellar bursa
223
What muscle is the chief flexor of the hip?
Psoas major
224
What component of the ANS, when stimulated, results in bronchoconstriction?
Parasympathetic stimulation, via the vagus nerve, results in Bronchoconstriction, whereas Sympathetic stimulation results in Bronchodilation.
225
What muscles in the hand Adduct the fingers?
The Palmar interosseus ADducts, whereas the Dorsal interosseus ABducts (PAD and DAB)
226
What type of cerebral bleed is due to a rupture of a berry aneurysm in the circle of Willis?
Subrachnoid hematoma
227
What are the five terminal branches of the facial nerve?
1. Temporal 2. Zygomatic 3. Buccal 4. Mandibular 5. Cervical (Two Zebras Bit My Clavicle.)
228
What structure of the knee is described thus? | C-shaped shock absorber; aids in attachment of the tibia to the femur via the medial collateral ligament
Medial meniscus
229
Prevents posterior displacement and has medial-to-lateral attachment on the tibia
Posterior cruciate ligament
230
Prevents adduction
Lateral collateral ligament
231
Prevents anterior displacement and has lateral-to-medial attachment on the tibia
ACL
232
Prevents abduction
Medial collateral ligament
233
What branches of CN X are the sensory and motor components of the Cough reflex? Be specific.
The Sensory component is through the Superior laryngeal nerve, and the Motor limb is via the recurrent laryngeal nerve.
234
What nerves provide sensory innervation above the vocal cords? Below the vocal cords?
The Internal laryngeal nerve supplies sensory information from Above the vocal cords while the Recurrent laryngeal nerve supplies sensory information Below.
235
EMBRYOLOGY | From what pharyngeal groove is the external auditory meatus derived?
First pharyngeal groove; all others degenerate.
236
What embryonic structure forms the adult male structure? | Corpus cavernosus, corpus spongiosum, and glans and body of the penis
Phallus
237
Scrotum
Labioscrotal swelling
238
Urinary bladder, urethra, prostate gland, bulbourethral gland
Urogenital sinus
239
Testes, seminiferous tubules, and rete testes
Gonads
240
Ventral part of the penis
Urogenital folds
241
Gubernaculum testes
Gubernaculum
242
Epididymis, ductus deferens, seminal vesicle, and ejaculatory duct
Mesonephric duct
243
Which PG is associated with maintaining a PDA?
PGE and intrauterine or neonatal asphyxia maintain Patency of the ductus arteriosus. Indomethacin, ACh, and catecholamines promote Closure of the ductus arteriosus.
244
When does the primitive gut herniate out the embryo?
6 weeks
245
When does it go back into the embryo?
10 weeks
246
What results when the Palatine prominences fail to fuse with the other side?
Cleft palate
247
What is the term for a direct connection between the intestine and teh external environment through the umbilicus because the vitelline duct persists?
Vitelline fistula
248
Where do the primordial germ cells arise?
From the wall of the yolk sac
249
What disorder is due to a 5-α-reductase deficiency, resulting in testicular tissue and stunted male external genitalia?
Male pseudo-intersexuality (hermaphrodite); these individuals are 46XY.
250
Does the zygote divide mitotically meiotically?
The zygote divides Mitotically; only germ cells divide meiotically.
251
During what embryonic week does the intraembryonic coelom form?
Third week
252
Name the Primary vesicle the following structures are derived from (proencephalon, mesencephalon, or rhombencephalon. Cerebral hemispheres
Proencephalon
253
Midbrain
Mesencephalon
254
Cerebellum
Rhombencephalon
255
Medulla
Rhombencephalon
256
Diencephalon
Proencephalon
257
Metencephalon
Rhombencephalon
258
Telencephalon
Proencephalon
259
Thalamus
Proencephalon
260
Eye
Proencephalon (diencephalon derivative)
261
Pons
Rhombencephalon
262
Myelencephalon
Rhombencephalon
263
Pineal gland
Proencephalon (diencephalon derivative)
264
Cerebral aqueduct
Mesencephalon
265
Neurohypophysis
Proencephalon (diencephalon derivative)
266
Third ventricle
Proencephalon
267
Hypothalamus
Proencephalon (diencephalon derivate)
268
Lateral ventricles
Proencephalon
269
What malignant tumor of the trophoblast causes high levels of hCG and may occur after a hydatidiform mole, abortion, or normal pregnancy?
Gestational trophoblastic neoplasia (GTN or choriocarcinoma)
270
What syndrome is due to a deficiency of Surfactant?
Respiratory distress syndrome; treatment with cortisol and thyroxine can increase production of surfactant.
271
How many oogonia are present at birth?
None; they are not formed until a girl reaches puberty.
272
What right-to-left shunt occurs when the aorta opens into the right ventricle and the pulmonary trunk opens into the left ventricle?
Transposition of the great vessels arises from a failure of the aorticopulmonary septum to grow in a spiral.
273
What are the adult remnants of the following structures? | Left umbilical vein
Ligament teres
274
Foramen ovale
Fossa ovale
275
Right and left umbilical arteries
Medial umbilical ligaments
276
Ductus arteriosus
Ligamentum arteriosum
277
Ductus venosus
Ligamentum venosum
278
Mandibular hypoplasia, down-slanted palpebral fissures, colobomas, malformed ears, and zygomatic hypoplasia are commonly seen in what pharyngeal arch I abnormality?
Treacher Collins syndrome
279
What is the tetrad of tetralogy of Fallot?
SHIP: Shifting of the aorta, Hypertrophy of the right ventricle, Interventricular septal defect, Pulmonary stenosis
280
What is the term for the external urethra opening onto the Ventral surface of the penis?
Hypospadia
281
What CN is associated with the | First pharyngeal arch?
CN V
282
Second pharyngeal arch?
CN VII
283
Third pharyngeal arch?
CN IX
284
Fourth pharyngeal arch?
CN X
285
Fifth pharyngeal arch?
None; it degenerates.
286
Sixth pharyngeal arch?
CN X
287
What disease results in a failure of neural crest cells to migrate to the myenteric plexus of the sigmoid colon and rectum?
Hirschsprung's disease (colonic gangliosus)
288
What immunologic syndrome is due to a pharyngeal pouch 3 and 4 failure?
DiGeorge's syndrome
289
What embryonic structure, around day 19, tells the ectoderm above it to differentiate into Neural Tissue?
The notochord
290
What is the term for failure of the testes to descend into the scrotum?
Cryptorchidism; normally the testes descend into the scrotum within 3 months of birth.
291
Is a membranous septal defect more commonly interventricular or interatrial?
Membranous septal defects are interventricular; a persistent Patent Ovale results in an Interatrial septal defect.
292
What pharyngeal pouch and groove persist when a pharyngeal fistula is formed?
The second pharyngeal pouch and groove
293
How early can a pregnancy be detected by hCG assays in the blood? In urine?
hCG can be detected in the blood by day 8 and in the urine by day 10.
294
From what pharyngeal pouch is the following structure derived? Middle ear
First
295
Superior parathyroid gland and ultimobranchial body of the thyroid
Fourth
296
Inferior parathyroid gland and thymus
Third
297
Palatine tonsil
Second | M PITS for pharyngeal pouch derivatives
298
What is the term for the external urethra opening onto the Dorsal surface of the penis?
Epispadia
299
True or false? In females, meiosis II is incomplete unless fertilization takes place.
True. The elimination of the unfertilized egg is menses.
300
What adult structures are derived from preotic somites?
Muscles of the internal eye
301
What disorder is associated with jaundice, white stools, and dark urine due to biliary duct occlusion secondary to incomplete recanalization?
Extrahepatic biliary atresia
302
What hormone, produced by the Syncytiotropholast, stimulates the production of Progesterone by the corpus luteum?
hCG
303
How many mature sperm are produced by one type B spermatogonium?
Four
304
All primary oocytes in females are formed by what age?
They are formed by the fifth month of fetal life.
305
From what embryonic structure are the following structures derived? The ascending aorta and the pulmonary trunk
Truncus arteriosus
306
The sinus venarum, coronary sinus, and the oblique vein of the left atrium
Sinus venosus
307
The right and left ventricles
Primitive ventricle
308
The aortic vestibule and the conus arteriosus
Bulbus cordis
309
The right and left atria
Primitive atrium
310
After a longstanding left-to-right shunt reverses, causing cyanosis, and becomes a right-to-left shunt, what is it termed?
Eisenmenger's syndrome
311
True or false? The thyroid gland is an embryologic foregut derivative.
True. The thyroid gland, the lungs, and the pharyngeal pouches are foregut derivatives that are not a component of the gastrointestinal system.
312
What embryonic structure forms the following adult structures? Collecting ducts, calyces, renal pelvis, and ureter
Mesonephric duct (ureteric bud)
313
Urinary bladder and urethra
Urogenital sinus
314
External genitalia
Phallus, urogenital folds, and labioscrotal swellings
315
Nephrons, kidney
Metanephros
316
Median umbilical ligament
Urachus
317
True or false? The epithelial lining of the urinary bladder and the urethra are embryologic hindgut derivatives.
True
318
Name the four ventral mesentery derivatives.
1. The lesser omentum (consisting of the hepatoduodenal and hepatogstric ligaments) 2. Falciform ligament 3. Coronary ligament of the liver 4. Triangular ligament of the liver Liver is ventral; all other ligaments are dorsal mesentery derivatives.
319
Projectile Nonbilious vomiting and a small knot at the right costal margin (olive sign) are hallmarks of what embryonic disorder?
Hypertrophic pyloric stenosis due to hypertrophy of the muscularis externa, resulting in a narrowed pyloric outlet
320
The separation of 46 homologous chromosomes Without splitting of the centromeres occurs during what phase of meiosis?
Meiosis I; disjunction With centromere splitting occurs during meiosis II.
321
Blood and its vessels form during what embryonic week?
Third week; they are derived from the wall of the yolk sac.
322
What embryonic structure forms the adult female structures? | Glans clitoris, corpus cavernosus, and spongiosum
Phallus
323
Gartner's duct
Mesonephric duct
324
Ovary, follicles, rete ovarii
Gonads
325
Uterine tube, uterus, cervix, and upper third of the vagina
Paranesonephric ducts
326
Labia majora
Labioscrotal swelling
327
Labia minora
Urogenital folds
328
Ovarian and round ligaments
Gubernaculum
329
Urinary bladder, urethra, greater vestibular glands, vagina
Urogenital sinus
330
What direction does the primitive gut rotate? What is its axis rotation?
The gut rotates clockwise around the superior mesenteric artery.
331
What syndrome occurs when a 46XY fetus develops testes and Female external genitalia?
Testicular feminization syndrome (Dude looks like a lady!)
332
Preeclampsia in the first trimester, hCG levels above 100,00 mIU/mL, and an enlarged bleeding uterus are clinical signs of what?
Hydatidiform mole
333
True or false? The foramen ovale closes just prior to birth.
False. It closes just After birth because the change in pulmonary circulation causes increased left atrial pressure.
334
At ovulation, in what stage of meiosis II is the secondary oocyte arrested?
Metaphase II
335
What is the name for failed recanalization of the duodenum resulting in polyhydramnios, bile-containing vomitus, and a distended stomach?
Duodenal atresia
336
What remains patent in a hydrocele of the testis, allowing peritoneal fluid to form into a cyst?
A patent processus vaginalis
337
True or false? The respiratory system is derived from the ventral wall of the foregut.
True. The laryngotracheal (respiratory) diverticulum is divided from the foregut by the tracheoesophageal septum.
338
What is the name for failure of the allantois to close, resulting in a urachal fistula or sinus?
Patent urachus
339
What structure is derived from the prochordal plate?
The mouth
340
What is the only organ supplied by the foregut artery that is of mesodermal origin?
Spleen
341
What tumor is derived from primitive streak remnants and often contains bone, hair, or other tissue types?
Sacrococcygeal teratoma
342
What two pathologic conditions occur when the gut does not return to the embryo?
Omphalocele and gastroschisis
343
True or false? For implantation to occur the zona pellucida must degenerate.
True. Remember, it degenerates 4 to 5 days post fertilization, and implantation occurs 7 days post fertilization!
344
What results when the Maxillary prominence fails to fuse with the medial nasal prominence?
Cleft lip
345
What is the direction of growth for the primitive streak, caudal to rostral or rostral to caudal?
The primitive streak grows caudal to rostral.
346
During what embryonic week do somites begin to form?
Third week
347
In men, at what embryonic week do the primordial germ cells migrate to the indifferent gonad?
Week four, and they remain dormant there until puberty.
348
What embryonic week sees the formation of the notochord and the neural tube?
Third week
349
What right-to-left shunt occurs when only one vessel receives blood from both the right and left ventricles?
Persistent truncus arteriosus
350
What three embryonic cell layers form the chorion?
1. Cytotrophoblast 2. Syncytiotrophoblast 3. Extraembryonic mesoderm
351
NEUROSCIENCE | Where are the Preganglionic neuron cell bodies, the CNS or the PNS?
They are in the grey matter of the CNS.
352
Which three CNs send sensory information to the Solitary Nucleus?
CN VII, IX, and X; taste and general sensation for the tongue is sent to the solitary nucleus.
353
What syndrome is associated with the following brainstem lesions? Vertebral artery or anterior spinal artery occlusion, resulting in Contralateral corticospinal tract and medial lemniscus tract deficits and an Ipsilateral CN XII lesion
Medial medullary syndrome
354
Contralateral corticospinal and medial lemniscus tract deficits and an Ipsilateral medial strabismus secondary to a lesion in CN VI
Medial pontine syndrome
355
Slow-growing Acoustic Neuroma producing CN VII deficiencies
Pontocerebellar angle syndrome
356
Occlusion of the PICA, resulting in Ipsilateral limb ataxia, Ipsilateral facial pain and temperature loss, Contralateral pain and body temparature loss, Ipsilateral Horner's syndrome, and Ipsilateral paralysis of the vocal cords, palate droop, dysphagia, nystagmus, vomiting, and vertigo
Lateral medullary (Wallenberg's) syndrome
357
AICA or superior cerebellar artery occlusion, resulting in Ipsilateral limb ataxia, Ipsilateral facial pain and temperature loss, Contralateral loss of pain and temperature to the body, Ipsilateral Horner's syndrome, Ipsilateral facial paralysis, and hearing loss
Lateral pontine syndrome
358
Posterior cerebral artery occlusion resulting in a Contralateral corticospinal tract signs, Contralateral corticobulbar signs to the lower face, and Ipsilateral CN III palsy
Medial midbrain (Weber's) syndrome
359
What CNs are affected if there is a lesion in | The midbrain?
CN III and IV
360
The upper medulla?
CN IX, X, and XII
361
Pontomedullary junction?
CN VI, VII, and VIII
362
The upper pons?
CN V
363
What is the only CN nucleus found in the cervical spinal cord?
Accessory nucleus
364
What component of the trigeminal nuclei | Supplies the muscles of mastication?
Motor nucleus of CN V
365
Receives sensory input (all but pain and temperature) from the face, scalp, dura, and the oral and nasal cavities?
Spinal trigeminal nucleus
366
Forms the sensory component of the jaw jerk reflex?
Mesencephalic nucleus
367
What deep cerebellar nuclei receive Purkinje cell projections in The flocculonodular lobe?
The lateral vestibular nucleus
368
The vermis?
The fastigial nucleus
369
The lateral cerebellar hemispheres?
The interposed nucleus
370
The intermediate hemispheres?
The dentate nucleus
371
What is the only Excitatory neuron in the cerebellar cortex, and what is its neurotransmitter?
The granule cell is the only Excitatory neuron in the cerebellar cortex, and it uses Glutamate as its neurotransmitter. All the other cells in the cerebellum are Inhibitory neurons, and they use GABA as their neurotransmitter.
372
What three CNs are associated with conjugate eye movements?
CN III, IV, and VI
373
What is the term to describe the soft, flabby feel and diminished reflexes seen in patients with acute cerebellar injury to the deep cerebellar nuclei?
Hypotonia (rag doll appearance)
374
What bedside test is used to differentiate a dorsal column lesion from a lesion in the vermis of the cerebral cortex?
The Romberg sign is present if the patient Sways or loses balance when standing with eyes Open. In a Dorsal column lesion, patients sway with eyes Closed. (Don't forget this one.)
375
Which one of the cerebellar peduncles is mainly responsible for Outgoing (Efferent) information?
Superior cerebellar peduncle; the Inferior and the Middle consist mainly of Incoming (afferent) tracts and fibers.
376
What tract carries Unconscious propiroceptive information from the Golgi tendon organs and muscle spindle to the Cerebellum, helping monitor and modulate muscle movements?
Lower extremity and lower trunk information travels in the dorsal spinocerebellar tract. The Upper trunk and extremity information travels in the cuneocerebellar tract. (Cuneocerebellar and fasciculus Cuneatus both apply to Upper extremities.)
377
What reflex, seen in lesions of the corticospinal tract, is an Extension of the great toe with Fanning the of remaining toes?
The Babinski reflex is present in UMN lesions. Muscle atrophy due to disuse, hyperreflexia, spastic paralysis, increased muscle tone, and weakness are commonly seen in UMN lesions.
378
What is the triad of Horner's syndrome?
Ptosis (eyelid drooping), Miosis (pupillary constriction), and Anhydrosis (lack of sweating) occur when the preganglionic sympathetic fibers from T1 to T4 are obstucted.
379
What component of the inner ear | Contains Perilymph and responds to angular acceleration and deceleration of the head?
Semicircular canal
380
Contains Endolymph and responds to head turning and movement?
Semicircular duct
381
Contains Endolymph and gravity receptors monitoring Linear acceleration and deceleration of the head, noting changes in head position?
Utricle and saccule
382
What is the name of demyelination of the corticospinal tract and the dorsal column in the spinal cord due most commonly to a vitamin B12 deficiency?
Subacute combined degeneration, which is bilateral below the level of the lesion.
383
What encephalopathy causes ocular palsies, confusion, and gait abnormalities related to a lesion in the Mammillary bodies and/or the Dorsomedial nuclei of the thalamus?
Wernicke's encephalopathy
384
Which thalamic nucleus receives auditory input from the inferior colliculus?
MGB
385
Where are the Postganglionic neuron cell bodies, the CNS or the PNS?
They are in Ganglia in the PNS.
386
What disease is a cavitation of the spinal cord causing bilateral loss of pain and temperature at the level of the lesion?
Syringomyelia
387
What nulceus of the hypothalamus receives visual input from the retina and helps set the circadian rhythm?
Suprachiasmatic nucleus
388
Are white rami preganglionic or postganglionic fibers?
White rami are Preganglionic fibers, whereas Grey rami are Postgangilionic fibers.
389
What area of the hypothalamus is responsible for recognizing a Decrease in body temperature and mediates the response to conserve heat?
Posterior hypothalamic zones; lesions here result in poikilothermy (environmental control of one's body temperature).
390
What CN transmits sensory information from the Cornea?
CN V1, the Occulomotor division of the Trigeminal nerve, is the sensory component of the corneal reflex.
391
What Preganglionic Sympathetic fibers are the smooth muscle and glands of the pelvis and the hindgut?
Lumbar splanchnics
392
Where are the cell bodies for the DCML and spinothalamic sensory systems?
The First sensory neuron is in the Dorsal root ganglia. It carries Ascending sensory information in the dorsal root of a spinal nerve, eventually synapsing with Second sensory neuron. In the Brainstem (DCML) and the spinal Spinal cord (spinothalamic) the second neuron cell body sends its axons to synapse in the Thalamus. The Third sensory neuron cell body is a thalamic nuclei that sends its fibers to the primary somatosensory cortex.
393
What term describes the reflex that increases the curvature of the lens, allowing Near vision?
Accommodation
394
What CN carries Preganglionic parasympathetic fibers that innervate the viscera of the neck, thorax, foregut, and midgut?
CN X (Remember, the vagus nerve supplies the parasympathetic information from the tip of the pharynx to the end of the midgut and all between.)
395
What area of the hypothalamus is responsible for recognizing an increase in body temperature and mediates the response to dissipate heat?
Anterior hypothalamic zone; lesions here result in Hyperthermia.
396
What Excitatory fibers arise from the Inferior olivary nuclei on the Contralateral side of the body?
Climbing fibers; they are monosynaptic input on Purkinje cells. Mossy fibers, also Excitatory, are axons of all other sources and synapse on Granule cells.
397
What four CN carry Preganglionic parasympathetic fibers?
CN III, VII, IX, and X
398
Name the form of spina bifida. | Meninges and spinal cord project through a vertebral defect
Meningomyelocele
399
Meninges project through a vertebral defect
Meningocele
400
An open neural tube hying on the surface of the back
Myeloschisis
401
Defect in the vertebral arch
Occulta | All except occulta cause elevated α-fetoprotein levels.
402
Name the thalamic nucleus based on its input and output. | Input from the optic tract; output projects to the primary visual cortex of the occipital lobe
LGB (think EYES)
403
Input from the trigeminal pathways; output to primary somatosensory cortex of the parietal lobe
Ventral posteromedial mucleus
404
Input from globus pallidus and the cerebellum; output to the primary motor cortex
Ventral lateral nucleus
405
Input from medial lemniscus and the spinocerebellar tracts; output to the primary somatosensory cortex
Ventral posterolateral nucleus
406
Input from globus pallidus and substantia nigra; output to primary motor cortex
Ventral anterior nucleus
407
Input from the amygdala, prefrontal cortex, and temporal lobe; output to the prefrontal lobe and the cingulated gyrus
Medial nuclear group (limbic system)
408
Input from inferior colliculus; output to primary auditory cortex
MGB (think EARS)
409
Input from the mammillary bodies via the mammillothalamic tract and the cingulated gyrus; output to the cingulated gyrus via the anterior limb of the internal capsule
Anterior nuclear group (Papez circiut of the limbic system)
410
What is the name of a thin brown ring around the outer edge of the cornea, seen in Wilson's disease?
Kayser-Fleischer ring
411
What do UMNs innervate?
They innervate LMNs.
412
What area of the brain serves as the major Sensory relay center for visual, auditory, gustatory, and tactile information destined for the cerebral cortex, cerebellum, or basal ganglia?
The thalamus (I like to think of the thalamus as the executive secretary for the cerebral cortex. All information destined for the cortex has to go through the thalamus.)
413
Which of the colliculi help direct the movement of both eyes in a gaze?
Superior colliculus (Remember S for Superior and Sight). The inferior colliculus processes auditory information from both ears.
414
How do the corticobulbar fibers of CN VII differ from the rest of the CNs?
Normally corticobulbar fiber innervation of the CNs is bilateral (the LMN receives information from both the left and right cerebral cortex), but with CN VII the LMN of the Upper Face receives Bilateral input but the Lower facial LMNs receive only Contralateral input.
415
What syndrome is described by a lesion in the angular gyrus (area 39) resulting in alexia, agraphia, acalculia, finger agnosia, and right-left disorientation?
Gerstmann's syndrome; spoken language is usually understood.
416
How many pairs of spinal nerves are associated with | Cervical vertebrae?
Eight pairs through seven cervical vertebrae.
417
Thoracic vertebrae?
Twelve pairs through twelve thoracic vertebrae.
418
Lumbar vertebrae?
Five pairs through five lumbar vertebrae.
419
Sacral vertebrae?
Five pairs through five sacral vertebrae.
420
Coccygeal vertebrae?
One pair with three to five coccygeal vertebrae. | Totaling 31 pairs of spinal nerves.
421
What are the three sites where CSF can leave the ventricles and enter the subarachnoid space? (Name the lateral and the medial foramina.)
Two Lateral foramina of Luschka and 1 Medial foramen of Monroe (L for Lateral and M for Medial)
422
What CNs arise from | The midbrain?
CN III and IV
423
The pons?
CN V, VI, VII, and VIII
424
The medulla?
CN IX, X, and XII | CN XI arises from the cervical spinal cord.
425
What disconnect syndrome results from a lesion in the corpus callosum secondary to an infarct in the anterior cerebral artery, so that the person can comprehend the command but not execute it?
Transcortical apraxia; Wernicke's area of the left hemisphere cannot communicate with the right primary motor cortex because of the lesion in the corpus callosum.
426
True or false? Glucose readily diffuse across the blood-brain barrier.
False. Water readily diffuse across the blood-brain barrier, but glucose requires carrier-mediated transport.
427
What encapsulated group of the nerve endings seen at the muscle-tendon junction responds to an increase in tension generated in that muscle? (This is dropping a box that is too heavy to carry.)
Golgi tendon organs are stimulated by Ib afferent neurons in response to an Increase in force or tension. The inverse muscle reflex protects muscle from being torn; it limits the tension on the muscle.
428
What chromosome 4, AD disorder is a degeneration of GABA neurons in the striatum of the indirect pathway of the basal ganglia?
Huntington's chorea; patients have chorea, athetoid movements, progressive dementia, and behavioral problems.
429
What syndrome is described as bilateral lesions of the amygdala and the hippocampus resulting in placidity, anterograde amnesia, oral exploratory behavior, hepersexuality, and psychic blindness?
Kluver-Bucy syndrome
430
By asking a patient to close the eyes while standing with feet together, what two pathways are you eliminating from proprioception?
When a patient closes the eyes while standing with feet together, the Visual and Cerebellar components of proprioception are removed, so you are Testing the dorsal columns. Swaying with eyes closed is a Positive Romberg's sign indicating a lesion in the dorsal columns. The Cold water caloric test mimics a brainstem lesion by inhibiting the normal reflex response. (COWS: Cold Opposite Warm Same)
431
What is the name of bilateral flaccid paralysis, hyporeflexia, and hypotonia due to a viral infection of the ventral horn of the spinal cord?
Poliomyelitis; it is a bilateral LMN lesion.
432
What branch off the vertebral artery supplies | The ventrolateral two-thirds of the cervical spinal cord and the ventrolateral part of the medulla?
Anterior spinal artery
433
The cerebellum and the dorsolateral part of the medulla?
PICA
434
What syndrome causes inability to concentrate, easy distractibility, apathy, and regression to an infantile suckling or grasping reflex?
Frontal lobe syndrome (lesion in the prefrontal cortex)
435
True or false? The presence of PMNs in the CSF is always abnormal.
True. Although the CSF normally contains 0 to 4 lymphocytes or monocytes, the presence of PMNs is always considered abnormal.
436
What cells lining the ventricles have cilia on their luminal surface to move CSF?
Ependymal cells
437
What is the most common site for an aneurysm in cerebral circulation?
The junction where the anterior communicating and anterior cerebral arteries join. As the aneurysm expands, it compresses the fibers from the Upper temporal fields of the optic chiasm, producing Bitemporal inferior quadrantanopia.
438
What fissure of the cerebral cortex runs perpendicular to the lateral fissure and separates the frontal and the parietal lobes?
Central sulcus (sulcus of Rolando)
439
What is the name of violent projectile movements of a limb resulting from a lesion in the subthalamic nuclei of the basal ganglia?
Hemiballismus
440
What is the term for the type of pupil seen in Neurosyphilis, and what ocular reflexes are Lost?
Argyll Robertson pupils accompany a Loss of both Direct and Consensual light reflexes, but the Accomodation-convergence reaction remains Intact. It can also be seen in patients with pineal tumors or multiple sclerosis.
441
True or false? Intrafusal fibers form muscle spindles.
True. Muscle spindles are modified skeletal muscle fibers. They are the Sensory component of the stretch reflexes.
442
What Brodmann area is associated with | Broca's area?
Areas 44 and 45
443
Primary auditory cortex?
Areas 41 and 42
444
Primary somatosensory cortex?
Areas 1, 2, and 3
445
Somatosensory association cortex?
Areas 5 and 7
446
Primary motor cortex?
Area 4
447
Premotor cortex?
Area 6
448
Visual association cortex?
Area 18 and 19
449
Frontal eye fields?
Area 8
450
Primary visual cortex?
Area 17
451
Wernicke's area?
Area 22 and occasionally 39 and 40
452
What is the fluid of the posterior compartment of the eye?
Vitreous humor
453
What aphasia produces a nonfluent pattern of speech with the ability to understand written and spoken language seen in lesions in the dominant hemisphere?
Expressive aphasia
454
In a topographical arrangement of the cerebellar homunculus map, what area or lobe Controls the axial and proximal musculature of the limbs?
The vermis
455
Is involved in motor planning?
Lateral part of the hemispheres
456
Controls balance and eye movements?
Flocculonodular lobe
457
Controls distal musculature?
Intermediate part of the hemispheres
458
What glial cell is derived from mesoderm and acts as a scavenger, cleaning up cellular debris after injury?
Microglia (Microglia and mesoderm both begin with M)
459
What direct-pathway basal ganglia disease is described by masklike facies, stooped posture, cogwheel rigidity, pill-rolling tremor at rest, and a gait characterized by shuffling and chasing the center of gravity?
Parkinson's disease (I can't underestimate all of the buzzwords in this question. Remember it.)
460
What artery supplies most of the lateral surfaces of the cerebral hemispheres?
Middle cerebral artery
461
What hypothalamic nucleus is responsible for the production of ADH?
Supraoptic nuclei; lesions here result in diabetes insipidus.
462
True or false? High-frequency sound waves stimulate hair cells at the Base of the cochlea.
True. High-frequency sound waves stimulate the hair cells at the Base of the cochlea, whereas Low-frequency sound waves stimulate hair cells at the Apex of the cochlea.
463
What cells of the retina sees in Color and needs bright light to be activated?
Cones (C for Color and Cones)
464
What cell's axons are the only ones that Leave the cerebellar cortex?
The Purkinje cell
465
What splachnic carries Preganglionic Parasympathetic fibers that innervate the hindgut and the pelvic viscera?
Pelvic splanchnic (They all begin with P.)
466
Is nystagmus defined by the fast or slow component?
Nystagmus is named by the Fast component, which is the Corrective attempt made by the cerebral cortex in response to the Initial slow phase.
467
Name the ocular lesion; be specific. | Left optic nerve lesion
Left eye anopsia (left nasal and temporal hemianopsia)
468
Right calcarine cortex lesion
Left homonymous hemianopsia
469
A right LGB lesion (in the thalamus)
Left homonymous hemianopsia
470
Optic chiasm lesion
Bitemporal heteronymous hemianopsia
471
A right lateral compression of the optic chiasm (as in aneurysms in the internal carotid artery)
Right nasal hemianopsia
472
Left Meyer's loop lesion of the optic radiations.
Left homonymous hemianopsia
473
What is the function of the cerebellum?
Planning and Fine-tuning of voluntary skeletal muscle contractions. (Think coordination.) Remember, the function of the Basal ganglia is to Initiate gross voluntary skeletal muscle control.
474
What is the name for inability to stop a movement at the intended target?
Dysmetria; this is seen in a finger-to-nose test.
475
If a lesion occurs Before the onset of puberty and arrests sexual development, what area of the hypothalamus is affected?
Preoptic area of the hypothalamus; if the lesion occurs After puberty, amenorrhea or impotence will be seen.
476
What sulcus divides the occipital lobe horizontally into a superior cuneus and inferior lingual gyrus?
Calcarine sulcus
477
Do α- or γ-motor neurons innervate extrafusal muscle fibers?
α-Motor neurons innervate Extrafusal muscle fibers (a motor unit), whereas γ-motor neurons innervate Intrafusal muscle fibers.
478
Contracting both medial rectus muscles simultaneously makes the images of near objects remain on the same part of the retina. What term describes this process?
Convergence
479
Will a Unilateral lesion in the spinothalamic tract result in a contralateral or ipsilateral loss of pain and tempature?
Contralateral. The spinothalamic tract enters the spinal cord and immediately synapses in the dorsal born, crosses over, and ascends Contralateral in the spinal cord, brainstem, thalamus, and postcentral gyrus.
480
What ganglion supplies the Postganglionic parasympathetic fibers to the ciliary muscles of the eye?
Ciliary ganglion
481
In what tract does Pain, Temperature, and Crude touch sensory information Ascend to the Postcentral Gyrus of the parietal lobe?
Spinothalamic tract (anterolateral system)
482
What CN nucleus receives auditory information from both ears via the cochlear nuclei?
Superior olivary nucleus
483
What Parasympathetic nucleus is found on the floor of the fourth ventricle and supplies Preganglionic fibers innervating the terminal ganglias of the thorax, foregut, and midgut?
Dorsal motor nucleus of CN X
484
What sensory system is affected in the late spinal cord manifestation of syphilis?
Bilateral degeneration of the Dorsal columns in the spinal cord secondary to syphilis is known as tabes dorsalis. A high-step gait is seen in patients with tabes dorsalis because of the inability to feel the ground beneath their feet.
485
What do LMNs innervate?
They innervate skeletal muscle.
486
What tract carries the Ipsilateral dorsal column fibers from the Lower limbs in the spinal cord?
The fasciculus gracilis (Graceful), which lies Closest to the midline of the spinal cord.
487
True or false? CSF is clear, hypertonic solution with higher concentrations of K+ and HCO3-, than the serum.
False. CSF is a clear Isotonic solution with Lower concentration of K+ and HCO3-. It does have higher concentrations of Cl- and Mg2+.
488
What type of fiber or fibers are carried in (answer motor, sensory, or both) Dorsal root?
Sensory
489
Dorsal rami?
Both
490
Ventral rami?
Both
491
Ventral root?
Motor
492
Dorsal root ganglion?
Sensory
493
Spinal nerve?
Both
494
Describe the loss for each of the following in a hemisection of the spinal cord. (Brown-Saequard syndrome) Dorsal column tract?
Ipsilateral loss At and Below the level of the lesion
495
Corticospinal tract?
Ipsilateral loss Below the level of the lesion
496
LMN?
Ipsilateral flaccid paralysis
497
Spinothalamic tract?
Contralateral loss Below and Bilateral loss At the level of the lesion
498
What area of the brain acts as the center for Ipsilateral horizontal gaze?
PPRF
499
What aphasia is seen as an inability to comprehend spoken language and speaking in a word salad?
Receptive aphasia is due to a lesion to Broadmann areas 22, 39, and 40; generally the patient is Unaware of the deficit.
500
What is the function of the basal ganglia?
Initiate and manage Gross skeletal muscle movement control
501
What artery is formed by the union of the two vertebral arteries?
The basilar artery is formed at the pontomedullary junction.
502
What disease is described by bilateral flaccid weakness of the upper limbs (LMN) and bilateral spastic weakness of the lower limbs (UMN) beginning at the Cervical level of the spinal cord and progressing up or down the cord?
Amyotrophic lateral sclerosis (Lou Gehrig's disease) is a LMN lesion At the level of the lesion and UMN lesion Below the level of the lesion.
503
Which dopamine receptor excites the direct pathway of the basal ganglia?
D1 receptor; Inhibition of the direct pathway occurs through the D2 receptors.
504
Does the direct or indirect basal ganglia pathway result in a decreased level of cortical excitation?
Although both pathways are associated with disinhibition, the Indirect basal ganglia pathway is associated with a Decreased level of cortical excitation.
505
What fissure of the cerebral cortex separates the frontal and temporal lobes rostrally and partially separates the parietal and temporal lobes?
Lateral fissure (fissure of Sylvius)
506
What area of the brain acts as the center for Contralateral horizontal gaze?
Frontal eye field (Brodmann area 8)
507
In an adult, where does the spinal cord terminate and what is it called?
The conus medullaris terminates at the level of the second lumbar vertebra.
508
If a patient with a cerebellar lesion has nystagmus, which way is the fast component directed, toward or away from the lesion?
The fast component is directed toward the affected side of a cerebellar lesion.
509
What area of the limbic system is responsible for attaching Emotional significance to a stimulus?
Amygdala; it helps imprint an emotional response in memory.
510
What is the term for making up stories regarding past experiences because of an inability to retrieve them?
Confabulation; it is commonly seen in Korsakoff's syndrome.
511
What frontal lobe cortex is associated with organizing and planning the intellectual and emotional aspect of behavior?
Prefrontal cortex; it is in front of the premotor area.
512
What is the largest mucleus in the midbrain?
The substantia nigra is the largest nucleus in the midbrain. It contains melanin and uses GABA and dopamine as its neurotransmitters.
513
Where is the lesion that produces these symptoms when a patient is asked to look to the Left? Left eye can't look to the the Left
Left abducens nerve
514
Right eye can't look Left, Left eye nystagmus, and convergence is intact
Right medial longitudinal fasciculus
515
Neither eye can look Left with a Slow drift to the Right
Left abducens nucleus or Right cerebral cortex
516
What area of the hypothalamus is the feeding center?
Lateral hypothalamic zone; lesions here result in aphagia. (Notice the difference between the feeding center and the satiety center; they are in different zones.)
517
In what pathway of the basal ganglia do lesions result in hyperactive cortex with hyperkinetic, chorea, athetosis, tics, and dystonia?
Indirect pathway (Tourette syndrome for example)
518
What happens to muscle tone and stretch reflexes when there is a LMN lesion?
The Hallmarks of LMN lesion injury are Absent or decreased reflexes, muscle Fasciculations, Decreased muscle tone, and muscle Atrophy (flaccid paralysis). Don't forget, LMN lesions are Ipsilateral at the level of the lesion!
519
In what pathway of the basal ganglia do lesions result in an underactive cortex with hypokinetic, slow, or absent spontaneous movement?
Direct pathway; a good example is Parkinson's disease.
520
What sided muscle weakness is seen in an UMN corticospinal tract injury Above the pyramidal decussation?
Contralateral muscle weakness when Above the decussation, whereas an UMN injury Below the pyramidal decussation results in Ipsilateral muscle weakness.
521
What area of the retina consists of only cones and has the greatest visual acuity?
Fovea
522
What tract carries the ipsilateral dorsal column fibers from the upper limbs in the spinal cord?
The fasciculus cuneatus
523
What CNS demyelinating disease is characterized by diplopia, ataxia, paresthsias, monocular blindness and weakness, or spastic paresis?
Multiple sclerosis
524
What part of the ANS (i.e., PNS or CNS) controls the constriction of the pupil in response to light?
Parasympathetic
525
With which CN are preganglionic parasympathetic axons arising from the Edinger-Westphal nucleus associated?
CN III
526
Ophthalmic artery is a branch of what artery?
Internal carotid artery
527
What thalamic relay nucleus do the mammillary bodies project to?
The anterior nucleus of the thalamus
528
What cells contribute to the blood-brain barrier and proliferate in response to CNS injury?
Astrocytes
529
What causes slow writhing movements (athetosis)?
Hypermyelination of the corpus striatum and the thalamus (seen in cerebral palsy)
530
What area of the brain is responsible for emotion, feeding, mating, attention, and memory?
The limbic system
531
What is the name of the postganglionic parasympathetic ganglion that innervates The papillary sphincter and ciliary muscle of the eye?
Ciliary ganglion. (These fibers are carried in CN III. Remember it like this: -ili- in ciliary ganglion looks like the III of CN III.)
532
The parotid gland?
The otic ganglion. (These fibers are carried in CN IX. Remember it like this: the -oti- is in both Otic ganglion and parOtid gland.)
533
The submandibular and sublingual glands?
The submandibular ganglion. (Submandibular ganglion innervates the submandibular gland; easy enough.)
534
The lacrimal gland and oral and nasal mucosa?
Pterygopalatine ganglion (I remember this as the only ganglion left.)
535
What neuronal cell bodies are contained in the Intermediate zone of the spinal cord? (T1-L2)
Preganglionic sympathetic neurons
536
What limb of the internal capsule is Not supplied by the middle cerebral artery?
Anterior limb of the internal capsule is supplied by the anterior cerebral artery.
537
What tract is responsible for voluntary refined movements of distal extremities?
Corticospinal tract
538
Craniopharyngiomas are remnants of what?
Rathke's pouch; they can result in compression of the optic chiasm.
539
Clarke's nucleus is the second ascending sensory neuron of which spinocerebellar tract?
Dorsal spinocerebellar tract; the Accessory cuneate nucleus is the second nucleus fro the Cuneocerebellar tract.
540
Name the three postganglionic sympathetic ganglia that receive input from thoracic splanchnics.
Celiac, aorticorenal, and superior mesenteric ganglias. (Remember all "Splanchnics" are Sympathetic except for the Pelvic splanchnics, which are Preganglionic Parasympathetic fibers.)
541
What is the only CN to arise from the dorsal surface of the midbrain?
CN IV
542
What basic reflex regulates muscle tone by contracting muscles in response to stretch of that muscle?
The myotatic relfex is responsible for the tension present in all Resting muscle.
543
Where are the LMN cell bodies of the corticospinal tract?
In the ventral horn of the spinal cord. UMN cell bodies are in the precentral gyrus of the frontal lobe.
544
What nucleus, found in the intemediate zone of the spinal cord, sends unconscious proprioception to the cerebellum?
Clarke's nucleus
545
The vertebral artery is a branch of what artery?
The subclavian artery
546
What muscle of the middle car is innervated by the mandibular division of CN V?
Tensor tympani
547
The fibers of nucleus gracilis and nucleus cuneatus cross at the medullary decussation and ascend contralateral to what thalamic relay nucleus?
VPL nucleus sends its fibers to synapse in the Postcentral gyrus of the parietal lobe.
548
What muscle of the middle ear is innervated by CN VII?
The stapedius muscle
549
What part of the inner ear contains the gravity receptors for changes in the position of the head?
Saccule and utricle
550
What nucleus supplies the preganglionic parasympathetic fibers to the ciliary ganglion?
Edinger-Westphal nucleus (via CN III)
551
What reticular nuclei synthesize serotonin from L-tryptophan and plays a role in mood, aggression, and inducing sleep?
The raphe nuclei
552
Will a patient with a unilateral lesion in the cerebellum fall toward or away from the affected side?
Patients with unilateral cerebellar lesions fall toward the side of the lesion.
553
A unilateral lesion in what nucleus will produce ipsilateral paralysis of the Soft palate?
Nucleus ambiguus, resulting in the uvula deviating away from the side of the lesion.
554
True or false? Neurons in the dorsal horn participate in reflexes.
True. They are the sensory component of a spinal reflex.
555
What ganglion receives preganglionic sympathetic fibers from T1 to L1-2 and innervates smooth muscle, cardiac muscle, glands, head, thoracic viscera, and blood vessels of the body wall and limbs?
Sympathetic chain ganglion
556
What preganglionic sympathetic fibers are responsible for innervating the foregut and the midgut?
Thoracic splanchnic fibers
557
Does light or darkness regulate the pineal gland?
Light regulates the activity of the pineal gland via the retinal-suprachiasmatic-pineal pathway.
558
Name the three hormones produced by pinealocytes.
Melatonin, serotonin, and CCK
559
Is the pH of CSF acidotic, alkalotic, or neutral?
The pH of CSF is 7.33, acidotic.
560
What ascending sensory system carries joint position, vibratory and pressure sensation, and discriminative touch from the trunk and limbs?
The DCML system. (Remember, everything but pain and temperature.)
561
What reflex enables the eyes to remain focused on a target while the head is turning?
The vestibulo-ocular reflex
562
What cells of the retina see in black and white and are used for night vision?
Rods
563
HISTOLOGY Name the muscle type based on these descriptions: Discontinuous voluntary contraction, multinuclear striated unbranched fibers, actin and myosin overlapping for banding pattern, triadic T tubules, troponin and desmin as Z disc intermediate filament.
Skeletal muscles
564
Continuous involuntary contraction, uninuclear striated branched fibers, actin and myosin overlapping for banding pattern, dyadic T tubules, Intercalated Discs, troponin and desmin as a Z disc intermediate filament.
Cardiac muscle
565
Involuntary contraction, uninuclear nonstriated fibers, actin and myosin not forming banding pattern; lack of T tubules, Gap junctions, and Calmodulin.
Smooth muscle
566
What segment of the small intestine is associated with Brunner's glands?
Duodenum
567
Who is responsible for passing on mitochondrial DNA genetic disorders?
MItochondria-linked disorders are always inherited from the Mother.
568
What part of a neuron receives information?
Dendrites receive information, whereas axons send information.
569
What type of collagen is associated with the basement membrane?
Type IV collagen
570
What is the epithelial lining of the Prostatic portion of the urethra?
Transitional epithelium. The distal portion of the Penile urethra is composed of Stratified epithelium.
571
What cell of the nephron is responsible for renin production and secretion?
Juxtaglomerular (JG) cell
572
What cell surface modification of ependymal cells and respiratory epithelium has a 9 + 2 microtubular configuration and movement as its function?
Cilia
573
True or false? The following are functions of hepatocytes: protein production, bile secretion, detoxification, conjugation, and lipid storage.
True. (They are quite a busy bunch of cells!)
574
What substance found in eosinophils is toxic to parasitic worms?
Major basic protein
575
After fertilization, what cells of the corpus luteum | Secrete progesterone?
Granulose cells secrete progesterone. After fertilization the granulose cells form from follicular cells.
576
Secrete estrogen?
Theca cells secrete estrogen. After fertilization the theca cells form from the theca interna.
577
What is the largest organ in the body?
Integument (skin and its derivatives)
578
On what layer of the epidermis does all mitosis occur?
Malpighian layer (made up of the stratum basale and stratum spinosum)
579
What ribosomal subunit binds first to the mRNA strand?
The small subunit (40S) binds first.
580
What is the T-cell area of the spleen?
PALS
581
What element is needed for the proper alignment of tropocollagen molecules?
Copper (Cu2+)
582
What type of cell surface projection lies on the lateral surface of cells closest to the apex and acts to seal off the outside environment from the rest of the body?
Zonula occludens (tight junctions)
583
What organelle is responsible for ribosomal RNA synthesis?
Nucleolus. Ribosomal assembly also takes place in the nucleolus.
584
What sweat gland type is associated with odor production and hair follicles and is found in the axilla?
APocrinE glands (APES is my memory aid) Axilla, Areola, and Anus all begin with A. APES are hairy (associated with hair follicles). They smell (odor production), and if confronted by an APE, your Adrenergic nervous system would be firing (innervation).
585
What papillae send their senses via chorda tympani of CN VII?
Fungiform papillae
586
True or false? The portal tract of the liver lobule is the first area to be oxygenated in the liver.
True. (Remember, blood flows from the portal tracts to the central vein, so it is the first area to receive blood and therefor oxygen.)
587
Match the chromosome and haploid number with the stage of sperm development, spermatid, spermatocyte (primary or secondary), spermatogonia (type A or B): 46/2n (divide meiotically)
Spermatogonia (type A)
588
46/4n
Primary spermatocyte
589
23/1n
Spermatid
590
46/2n (divide mitotically)
Spermatogonia (type B)
591
23/2n
Secondary spermatocyte
592
What are the four functions of SER?
Steroid synthesis, drug detoxification, triglyceride resynthesis, and Ca2+ handling
593
Which immunoglobulin is secreted by the plasma cells in the gastrointestinal tract?
IgA
594
What area of the lymph node is considered the thymic-dependent area?
The inner cortex (paracortex) contains the T cells, so it is considered the thymic-dependent area.
595
What type of chromatin is transcriptionally inactive?
Heterochromatin, the light stuff in the nucleus on an electron microscope image.
596
Both submandibular and sublingual glands are innervated by CN VII (facial) and produce mucous and serous secretions. Which one mainly produces serous secretions?
Submandibular gland produces mainly Serous and the sublingual gland produces mainly Mucous secretions.
597
What is the only neuroglial cell of mesodermal origin?
Microglia. All others are neuroectodermal derivatives.
598
Where is tropocollagen aggregated to form a collagen fibril?
Outside the cell
599
What are the four posttranslational modifications done by the Golgi apparatus?
1. Phosphorylation of mannose (lysosomes only) 2. Removal of mannose residues 3. Formation of glycosylate proteins 4. Phosphorylation of sulfate amino acids
600
What is the epthelial cell lining the nasopharynx?
Stratified squamous nonkeratinized epithelium, which has cilia that beat toward the oropharynx.
601
What are the three epidermal derivatives?
1. Nails 2. Hair 3. Sweat glands (both apocrine and sebaceous)
602
What are the long microvilli in the inner ear and male reproductive tract called?
Stereocilia
603
True or false? The central vein of the liver lobule is the first area affected during hypoxia.
True. Blood flows from the portal tracts (distal) to the central vein (proximal), so it is the first area affected during hypoxia.
604
What cell of the male reproductive system produces testosterone?
Leydig cells produce testosterone. LH stimulates Leydig cells. (Both start with L.)
605
Myelin is produced by which cells in the PNS? In the CNS?
In the PNS, myelin is produced by Schwann cells, in the CNS by oligodendrocytes.
606
What cell type of the epidermis functions as antigen-presenting cells?
Langerhans cells (found in the stratum spinosum)
607
What cell type is found in the peripheral white pulp of the spleen?
B cells are mainly found in the peripheral white pulp and germinal centers in the spleen.
608
What area of the female reproductive tract is lined by stratified squamous epithelium rich in glycogen?
The vagina
609
What encapsulated lymphoid organ is characterized by presence of Hassall's corpuscles, and absence of germinal centers and B cells?
Thymus gland. (Thymus gland is essential for T cell maturation.)
610
What cell transports IgA, is secreted by plasma cells, and is in Peyer's patches to the gastrointestinal lumen?
M-cells
611
What are the cells of the parathyroid gland that produce PTH?
Chief cells
612
What skin type on the palms and soles is characterized by the absence of hair follicles and presence of stratum lucidum?
Thick skin
613
What is the name of hydrophilic pores that allow the direct passage of ions and particles between two adjacent cells?
Gap junctions
614
What type of lysosome is formed when lysosome fuses with a subtrate for breakdown?
Secondary lysosome (think of the primary as Inactive and secondary as Active)
615
What cell membrane structure increases the surface area of a cell and has actin randomly assorted within its structure?
Microvillus
616
What are the four components of the basement membrane?
1. Laminin 2. Heparan sulfate (heparitin sulfate) 3. Fibronectin 4. Type IV collagen
617
What organelle synthesizes proteins that are intended to stay within the cell?
Free polysomes. Membrane-associated polysomes are the site of protein synthesis destined to leave the cell.
618
What cell type of the body or fundus of the stomach secretes IF?
Parietal cells (Remember, they secrete HCl, too.)
619
What cell type of the body or fundus of the stomach secretes pepsinogen?
Chief cells
620
What hormone, produced by the granulose cell, stimulates the endometrium to enter the Proliferative phase?
Estrogen; the first 14 days of the female reproductive cycle mark the proliferative phase.
621
What cells of the nephron function as sodium concentration sensors of the tubular fluid?
Macula densa
622
What type of chromatin is transcriptionally Active?
Euchromatin, the dark stuff in the nucleus on an election microscope image.
623
What cells of the thyroid gland secrete calcitonin?
Parafollicular C cells
624
True or false? The nucleus is the site of Transcription.
True. Transcription (conversion of DNA to RNA), as well as replication, occurs in the nucleus.
625
How many days After the LH surge is ovulation?
One day after the LH surge and 2 days after the estrogen peak.
626
In what layer of the epidermis is melanin transferred from melanocytes to keratinocytes?
Stratum spinosum
627
What cells of the epidermis, derived from the neural crest, act as mechanoreceptors?
Merkel cells (Merkel's tactile cells)
628
What substance do the JG cells of the kidney secrete in response to low blood pressure?
Renin
629
What is the rule of one-third regarding muscle type of the esophagus?
Upper third skeletal muscle, Middle third both skeletal and smooth muscle, and Lower third smooth muscle
630
What papillae are responsible for sweet taste?
Circumvallate papillae
631
What area of the lymph node contains germinal centers?
The outer cortex contains most of the germinal centers and therefore also most B cells.
632
True or false? The gallbladder functions to produce bile.
False. The gallbladder does NOT produce bile, but it Concentrate bile via active sodium transport; water follow the sodium.
633
True or false? Depolarization of the postsynaptic membrane excites the neuron.
True. Hyperpolarization inhibits the postsynaptic membrane.
634
In the alveoli, what cell type is | for gas exchange?
Type I pneumocytes
635
responsible for producing surfactant?
Type II pneumocytes
636
part of the mononuclear phagocytic system?
Alveolar macrophages (dust cells)
637
Which trophoblast layer of the placenta remains until the end of pregnancy?
Syncytiotrophoblast. (The cytotrophoblast gets incorporated into syncytiotrophoblast.)
638
What is the first epidermal layer without organelles and nuclei?
Stratum lucidum
639
What area of the small intestine is characterized by Peyer's patches?
Ileum
640
What lymphoid organ has the following characteristics: outer and inner cortical areas, encapsulation, germinal centers, and high endothelial venules?
Lymph nodes
641
What area of the nephron is sensitive to the effects of ADH?
Collecting ducts, which make them readily permeable to water reabsorption.
642
What is the name of RER in neurons?
Nissl substances; there is a great deal of RER in neuron cell bodies, indicating high protein synthesis.
643
What hormone causes milk letdown?
Oxytocin
644
What are the three reasons for the effectiveness of the blood-brain barrier?
1. Tight junctions 2. Capillaries that lack fenestration 3. Very selective pinocytosis by the capillaries
645
What cell type of the epidermis originates from the neural crest?
Melanocytes
646
If no fertilization occurs, how many days after ovulation does the corpus luteum begin to degenerate?
12 days after ovulation
647
What area of the spleen consists of splenic cords of Billroth and phagocytoses RBCs?
Red pulp (Remember, Red pulp and RBCs begin with R.)
648
What is the name of the protein coat that surrounds the nuclear envelope?
Vimentin
649
What papillae are touch receptors on the tongue and send their sensations via CN V3 (mandibular division)?
Filiform papillae
650
What is the most superficial layer of the epidermis?
Stratum corneum (keratinized)
651
What syndrome is characterized by dynein arm abnormality resulting in chronic sinusitis, recurrent pulmonary infections, and infertility?
Kartagener's syndrome (also known as immotile cilia syndrome)
652
What are the functions of the zonula occludens and the zonula adherens?
To provide attachment between contiguous cells and to maintain a semipermeable barrier
653
What is the name of the SER of striated muscle?
Sarcoplasmic reticulum
654
Where do sperm go for maturation?
Ductus epididymis, which is lined by pseudostratified epithelium with stereocilia.
655
When is the first arrested stage of development in the female reproductive cycle?
Prophase of meiosis I (between 12th and 22nd week in utero)
656
What is the longest and most convoluted segment of the nephron?
PCT
657
What cells of the epidermis carry the pigment melanin?
Keratinocytes, the most numerous cells in the epidermis, carry Melanin and produce Keratin.
658
What segment of the gastrointestinal tract lacks villi, has crypts, and actively transports sodium out of its lumen?
Large intestine. Water is Passively removed from the lumen.
659
What two areas of the skin do NOT contain sebaceous glands?
Palms and soles of the feet. Sebaceous glands are associated with hair follicles, which are lacking on the palms and soles of the feet.
660
Which of the following is NOT part of the conducting portion of the respiratory system: trachea, bronchi, alveoli, or larynx?
Alveoli; they are part of the respiratory portion.
661
Where are the enzymes for the ETC and oxidative phosphorylation found?
The inner membrane of the mitochondria (cristae)
662
What lymphoid organ is characterized by germinal centers, plasma cells that secrete IgA, and NO encapsulation?
Peyer's patch
663
What generate Anterograde transport of information in a neuron?
Kinesins. Dynein generates Retrograde transportation of information.
664
What is the only glycosaminoglycan (GAG) that binds to the linker portion of the proteoglycan?
Hyaluronic acid (all sulfates bind to the core protein)
665
What cell in bone is a part of the mononuclear phagocytic system?
Osteoclasts
666
What three factors do Sertoli cells produce for normal Male development?
Inhibin, mullerian-inhibiting factor, and androgen binding protein
667
What epidermal layer's function is to release lipids to act as a sealant?
Stratum granulosum
668
What does the tunica intima of arteries have that veins do not?
An internal elastic lamina
669
Do the duct or the acini cells of the pancreas secrete HCO3-?
Duct cells secrete HCO3-, electrolytes, and water. The acini secrete the Enzymes necessary for carbohydrate, nucleic acid, protein cleavage, and emulsification of fats.
670
What cell of the duodenum contains high concentrations of lysozymes and has phagocytic activity?
Paneth cells
671
What maintains the osmotic gradient that is critical to the concentrating ability of the kidney?
The venae recta maintain the gradient via countercurrent flow.
672
Are the JG cells of the nephron a part of the afferent or efferent arteriole?
Afferent arteriole
673
What cell of the duodenum secretes CCK?
Enteroendocine (EE) cells; they also secrete secretin.
674
What are the proteoglycans of cartilage and bone?
Chondroitin sulfate and keratan sulfate
675
What is the term for the first 3 to 5 days of the female reproductive cycle?
Menses. (Ovulation occurs 14 days before the beginning of menses.)
676
What is the second arrested stage of development in the female reproductive cycle?
Metaphase of meiosis II (in the oocyte of the graafian follicle)
677
What ribosomal subunit sizes do eukaryotic cells have?
60S and 40S. The large subunits (60S) are made in the nucleolus and the small subunits (40S) are made in the nucleus.
678
What term describes how an action potential is propagated along an axon?
Saltatory conduction
679
What phase of the female reproductive cycle is 14 days long?
The secretory phase is Progesterone-dependent and 14 days long, whereas the length of the proliferative phase varies.
680
A single mRNA strand translated by a ribosome is termed what?
Polysome. Ribosomes read from the 5' to the 3' end of the mRNA.
681
What cell is under control of FSH and testosterone; secretes inhibin, MIF, and androgen-binding protein; and phagocytizes the excess cytoplasm of the spermatid?
Sertoli cell
682
What histone binds to nucleosomes together?
H1 histones
683
What is the major inorganic component of bone?
Hydroxyapatite
684
What cells of the adrenal gland are neural crest derivatives?
Chromaffin cells (adrenal medulla)
685
Where does β-oxidation of very long chain fatty acids begin?
In the peroxisome until it is 10 carbons long; the rest is completed in the mitochondria.
686
What organelles make ATP, have their own dsDNA, and can synthesize protein?
Mitochondria