L80: Reproduction 2 Flashcards Preview

FHB - Endocrinology (by Richie) > L80: Reproduction 2 > Flashcards

Flashcards in L80: Reproduction 2 Deck (40)
1

Seminal vesicles secrete

prostaglandins - stimulate uterine/fallopian tube contractions

2

Prostate gland secretes

alkaline secretions

3

In what accessory gland do sperm gain motility and lose cytoplasm? And is a reservoir for sperm? Stabilize acrosome?

Epididymis

4

Which of the following gonadal hormones is NOT a negative inhibitor of the pituitary?

A. Activin

B. Inhibitin

C. Follistatin

D. Testosterone/Estrogen

A. Activin

5

Which does NOT negatively feedback on hypothalamus?

A. Inhibin

B. Testosterone/Estrogen

C. Dopamine/Endorphins

D. Norepinephrine

D. NE

6

Which of the following PROMOTES release of LH and FSH?

A. Inhibin

B. Dopamine/Endorphins

C. Testosterone/Estrogen

D. Continuous exposure to GnRH

E. Pulsatile exposure to GnRH

E. 

7

Whats the major regulator of FSH?

inhibin

8

What's the major regulator of LH?

Testosterone

9

What does corpus luteum secrete?

Progesterone

10

Whats an acrosome on a spermocyte?

"A cap of membranes containing digestive enzymes"

11

Estradiol is carried by what binding protein?

SHBG

12

Progesterone is transported in blood by what carrier protein?

CBG

13

What is the most hydrophilic hormone on this table?

Androstendione

14

What is the most hydrophobic hormone on this table?

Dihydrotestosterone

15

what mechanism keeps the testes at the right temperature

counter-current heat exchange 

16

What stage of spermatogenesis, does the acrosome form? 

Spermiogenesis

17

Formation of residual body occurs in what stage of spermatogenesis?

Spermeation

18

During spermiogenesis, developing sperm are attached to the sertoli cell via

tight junction

19

Gametes are immunologically distinct from parent. It is protected from the parent immune system via

tight junctional border in testes

20

Prostaglandins, secreted from the seminal vesicles, promote

contraction of the uterus and fallopian tubes.

21

bodybuilders coming off steroids take

hCG

22

If spermatogenesis is TOO FAST, the developing germ cell release signals to Sertoli, which increase release of _____

inhibin which negatively regulates ant. pituitary release of FSH

23

If spermatogenesis is too slow, then sertoli cells secrete less ___________ which releases suppression of ant. pituitary to secrete _______

inhibin, FSH

24

NO stimulates _________, producing cGMP that leads to vasodilation

guanylyl cyclase

25

Which vein collapses during erection, preventing blood outflow?

Superficial dorsal vein

26

Emission is under control of 

sympathetic spinal reflex

27

give me an example of hypogonadotrophic hypogonadism

hyperprolactinemia (strong negative feedback of prolactin on hypothalamus)

28

give me 3 examples of incomplete androgen insensitivity

A. Testosterone receptor defect

B. Testosterone pathway defect

C. 5-alpha reductase deficiency

29

zona pellucida

"egg shell" made of mucopolysaccharide immediately around oocyte formed by granulosa cells

30

cumulus oophorus

granulosa cell that docks oocyte to wall of follicle

31

How does the graafian follicle grow?

Antral fluid increases as mucopolysaccharides depolymerize and pull water

32

How does the oocyte move into fallopian tubes

fimbrae sweep it in

33

corpus luteum secretes

progesterone

34

if fertilization doesnt occur

luteolysis

35

main action of activin

stimulates FSH release

36

Which inhibin is from the dominant graafian follicle?

inhibin B

37

What inhibin is from the corpus luteum?

inhibin A

38

What is the rate limiting step in ovarian steroid biosynthesis

Cholesterol to pregnenalone via desmolase

39

What is E1

estrone

40

What is E2

Estradiol (dominant estrogen)