L83: Pregnancy and Partuition Flashcards Preview

FHB - Endocrinology (by Richie) > L83: Pregnancy and Partuition > Flashcards

Flashcards in L83: Pregnancy and Partuition Deck (12)
1

Relaxin is produced by

corpus luteum and placenta

2

Marker of fetal wellbeing

estriol

3

Although estriol is the major estrogen of pregnancy,

it has weak estrogenic activity.

4

The placenta has limited capacity to synthesize cholesterol and relies almost exclusively on ______ as its cholesterol source.

maternal LDL

5

Ferguson reflex

Cervical stretch induces OXY release from post. pituitary. OXY promotes prostaglandin release. OXY also promotes hemostasis of placental vessels. Prostaglandins promote cervical contractions.

6

Let down reflex

OXY induced secretion of milk from nipples, in response to suckling or even auditory sounds (eg. baby crying). OXY induces contraction of myoepithelial cells and alveoli and smooth muscle of duct walls causing “milk letdown” for infant.

7

The most dominant signal for partition is

Decreased progesterone, increased estrogen

8

alpha adrenergic receptor

stimulates myometrial contraction

9

beta-adrenergic receptor

inhibits myometrial contraction

10

Aside from high estrogen:progesterone ratio, what other factors can precipitate labor?

Cortisol and catecholamines

11

Does OXY initiate labor?

No. It plays a role after initiation.

12

What does estrogen do to oxytocin receptors?

increases expression to potentiate the effect of OXY (myometrial contractions)