Law Review GENERAL Clinical Flashcards
(243 cards)
Rivabirin and pregnancy? how long after can a patient get pregnant?
contraindicated in pregnancy , even a guy who is taking hep C cant have sex with a girl cuz she might have a baby with defects
-must wait 6 months after stopping therapy
Rivabirin and the kidney
Contraindicated at ClCR less than 50
Pegasys to generic
peginterferon 2g
What happens when a patient gets anemia or neutropenia with hepatitis C treatment?
doctor can prescribe epoetin for anemia
or filgastrim for neutropenia (neupogen)
Entecavir Brand
FOOD?
Baraclude
NO FOOD
peginterferon + rivabirin Brand
Rebetron
interferons and medguides
always dispense
Boceprivir/teleprivir
- indication
- MOA
- frequency
- pregnancy
Hepatitis C
protease inihibitors
-every 7 to 9 hours around the clock
-need negative pregnancy test before initial refill and before each refill
-must use two non hormonal contraceptives
NRTI class side effects
-lactic acidosis: muscle weakness, feet , cant move arms
-Headache fatigue, nausea, diarrhea
-skin rash
ALL possible
Epivir to Generic
Epivir HBV to generic
lamivudine for HIV
epivir HBV has a lower dose that is indicated for hepatitis
what meds cover bacteroides fragilis
tigecycline metronidazole Amp sulbactam cefoxitin, cefotetan ertapenem
nitrofurantoin
- indication
- Se
- Serious side effect
- renal adjustment
only for cystitis NOT systemic symptoms of UTI since does not reach good systemic concentraiton
- causes yellow brown urine that sotpes when you DC
- can cause serious lung problems
- CI at ClCR less than 60
biaxin to generic
MOA/Class
SE
DDI
clarithromycin
macrolide inhibiting 50 s
GI abmnormalities
3A4 inhibitor
amphotericin B
- compatibility
- why use the lipid formulation
- pregnancy
- side effects
ONLY D5W
- use lipid formulations to decrease infusion reactions and decrease nephrotoxicity
- pregnancy category B
- SE nephrotoxicity and electrolyte imbalances
what do you give to someone who has Cdiff but it it refractory to vancomycin and metronidazole?
Fidaxomicin
main rifampin side effects
hepatotoxicity and red orange urine
treatment for cytomegalovirus
cidofovir
valgancyclovir
foscarnet
clindamycin brand
spectrum
Cleocin
Covers gram + strept/staph but not enterococcus, gram + anaerobes
gram - anaerobes
daptomycin
- type of killing
- concentration or time dependent
- renal
- SE
- compatibility
- bacteriocidal
- concentration dependent
- Adjust renally
- myopathy of adem… (?)
- NS only
antibiotics with SLE - like side effects?
isoniazid
microdantin versus macrobid frequency
100 QID
100 BID
sinusitis doxycyline dose
100mg twice daily for 7-14 days
Does voriconazole cover aspergilis?
Yes
oseltamivir dose
75mg po twice daily for 5 days ( within the first 2 days of symptoms)