Lec 30 Endocrine System Flashcards

1
Q

describe the negative feedback mechanism

A

hormone level decreases -> secretion of hormone inc -> hormone level inc -> glands stop secreting hormone (since there is now enough)

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2
Q

where is the pituitary gland located?

A

interior surface of brain
attached to hypothalamus
surrounded by wall of willis

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3
Q

what is the structure of the pituitary gland?

A

2 distinct lobes -> adenohypophysis, neurohypophysis

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4
Q

what is the difference between adenohypophysis and neurohypophysis?

A
adenohypophysis -
no storage, production instead.
anterior
glanduar portion (produces)
produces and secretes 6 major hormones
neurohypophysis
posterior
storage
nervous portion
stores and releases 2 hormones by hypothalamus
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5
Q

what are the hormones secreted by the pituitary?

A

growth hormone, thyroid stimulating hormone, adreonocroticotropic hormone, follicle stimulating hormone (FSH), luteinizing hormone (LH), prolactin, oxytoxin, antidiuretic hormone

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6
Q

what is the action of growth hormones?

A

increases protein synthesis & mitosis

regulates growth of most cells of the body

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7
Q

what is the action of ACTH?

A

controls secretions of hormones of the adrenal cortex

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8
Q

what is the action of luteinizing hormone?

A

plays role in ovulation

stimulates secretion of sex hormones

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9
Q

what is the action of prolactin?

A

secretion of milk from mammary glands

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10
Q

what is the action of oxytocin?

A

stimulates uterine contractions

promotes milk ejection from breast

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11
Q

what is the action of antidiuretic hormone?

A

affects permeability of the kidney tubules to reduce the excretion of water

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12
Q

which 2 hormones secreted by the pituitary is made in the hypothalamus

A

oxytocin and ADH

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13
Q

where is the thyroid gland located?

A

anterior neck inferior to larynx

surrounds anterior and lateral aspect of trachea

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14
Q

what hormones are secreted by the thyroid gland

A

throxine (T4), triiodothromine(T3), calcitonin

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15
Q

what is the structure of throxine and triiodothyromine?

A

2 lobes connected by an isthmus, may contain pyramidal lobe

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16
Q

what is the effect of the thyroxine and triiodothyromine glands?

A

regulates metabolic rate

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17
Q

what is the structure of calcitonin?

A

cuboidal cells - hormone production

follicles - store hormones

18
Q

what effect does calcitonin have?

A

regulates osteoclast activity and lowers blood calcium levels

19
Q

where is the parathyroid gland located?

A

embedded on posterior side of thyroid gland

20
Q

where is the site of action for the parathyroid gland?

A

osteoclast in bone, kidney, intestine

21
Q

what is the effect of the parathyroid gland?

A

increase in blood calcium levels

22
Q

where are the adrenal glands located?

A

superior pole of the kidneys

23
Q

what hormones are secreted by the adrenal glands?

A

androgens (estrogen / progesterone)
epinephrine
aldosterone (mineracorticoid)
cortisol hydrocortison (a glucocorticod)

24
Q

where is the site of action of aldosterone?

A

kidney tubules

25
what is the effect of aldosterone?
regulates Na & K levels
26
what is the effect of cortisol hydrocortison?
prevent/ reduces inflammation
27
what hormone do beta and alpha cells secrete?
beta - insulin | alpha - glucagon
28
which part of the pancreas contains the beta and alpha cells?
endocrine
29
where is the site of action for exocrine cells?
ducts
30
what is the effect of beta cells vs alpha cells?
beta cells regulate transport of glucose into cells | alpha cells convert glycogen into glucose
31
what hormone does the pineal gland secrete?
melatonin
32
what does ACTH stand for?
adrenocorticotropic hormone
33
what does TSH stand for?
thyroid stimulating hormone
34
what is the difference between prolactin and oxytocin?
prolactin produces milk, oxytocin ejects milk
35
which 2 hormones in the pituitary stimulate sex hormone secretion?
follicle stimulating | lutenizing hormone
36
what is the effect of the thyroid gland?
regulates basal metabolic rate
37
where is the site of action for thyroid gland?
most cells
38
where is site of action for calcitonin?
bones
39
which hormones of the adrenal gland are made in the cortex?
androgens, aldosterone, cortisol hydrocortison
40
which hormone of the adrenal glands are made in the medulla?
epinephrine
41
what is the inner portion and outer portion of the adrenal glands?
inner - medulla | outer - cortex