lecture 10 Flashcards
(22 cards)
endothelium is avascular except
the chochlear duct that possess stria vasularis
what are 3 ways to classify epithelia
1) via layers- simple has one layer at the basement membrane
stratified has multilayers
2)cell shape in the superficial layer on stratified epithelia (sqamous, cuboidal, columnar)
3) keratinized/not
squamous vs columnar vs cuboidal
squamous is flat
columnar is column shaped
cuboidal is cubed
transitional epithelia
balloon shaped outer layer and relaxed or contracted (like in a urinary bladder that’s not full)
pseudostratified epithelia
one layer but have multiple sizes and shapes of cells but all attached to basement lamina
where is simple squamous found?
in the aveoli of lungs and in blood vessels
what is simple squamous epithelium function?
blood-brain barrier, filtration and exchange
where are simple cuboidal epithelia found?
what are their main functions?
thyroid particles, renal tubules and ducts of glands
absorption, excretion, barrier, conduit
where are simple columnar epithelia found and what are their main functions
found in uterine tubes, stomach and intestines
for absorption, secretion and barrier
pseudostratified epithelia are found where? function?
trachea, bronchi and ducts of male reproductive system
secretion, absorption, barrier and transport
squamous keratinized vs nonkeratinized
keratinized in skin
nonkeratinized in vagina, esophogous and distal anal canal
squamous cell carcinoma
change nonkeratinized tissue to keratinized
= keratin pearls
where are transitional squamous epithelia loacted? function?
they are found in urinary bladder, urethra, ureter
they are for distention, protection and barrier
cilium
have 9-2 array at top 9-3 at bottome made of microtubules with multiple dyenin-ATPase proteins used in motility
primary cilium
missing the two central microtubules
non-motile
key role in tissue morphogenesis
play role in chemosensors, osomoreceptors, and mechanorectors
polycystic kidney disease
mutation in polycystin 1 or 2 that causes the mitotic spindle in renal cells to form incorrectly causing a horizontal growth of the tubule and the diameter is going to get greater and greater until you have cysts
what do the celia in the primitive node do?
they direct flow thru the primitive flow correctly to provide the left right axis
microvilla made of
microfilaments
where do the microvilla terminate and what’s down there
terminal web,
actin, myosin and myosin 2 which has atp activity that bring the microvillae closer or further away that allows you to absorb or not absorb as much based on surface area
brush border
mature microvillae
pas positive
stereocelia
more like stereovilli non motile elongated microvilli actin found in male reproductive ducts and inner ear
car tangier ciliopathy
chronic sinitus- inflammation of mucosa
bronchiectasis- dilation of bronchi
situs inversus- abdominal stuff on wrong sides
