Lecture 16: Mediastinum, Lungs, Pleura Flashcards

(32 cards)

1
Q

what structures are found w/in the mediastinum

A

heart, great vessels, esophagus, trachea, autonomic and phrenic nerves, thymus, thoracic duct

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2
Q

what organs do the great vessels supply blood to?

A

head, neck, thoracic limbs

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3
Q

what spinal cord levels is the phrenic nerve located

A

C5-C7

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4
Q

sheets of mesothelium (single cell layer) that secrete small amounts of fluid and compost the pleura

A

serous membrane layer

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5
Q

what is the function of pleura

A

allows the external surfaces of lung lobes to smoothly glide during expansion and deflation

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6
Q

the out pouching of the foregut forms the ??

A

respiratory diverticulum AKA tracheobronchial diverticulum

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7
Q

what does the tracheobronchial tube form

A

larynx, trachea, lungs

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8
Q

what is the visceral pleura adherent to? what is the parietal (costal) pleura adherent to?

A

Visceral pleura - lung surface
Parietal (costal) pleura - body wall

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9
Q

what is central circulation and its inlet/outlet

A

blood supply to the heart
inlet: coronary arteries
outlet: cornonary sinus

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10
Q

what is systemic circulation and its inlet/outlet

A

oxygenated blood flow to the body

inlet: aorta
outlet: vena cavae

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11
Q

what is pulmonary circulation and its inlet/outlet

A

poorly oxygenated blood flow to the lungs for gas exchange
inlet: pulmonary arteries
outlet: pulmonary veins

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12
Q

where are the great vessels located

A

cranial mediastinum

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13
Q

what is the name of the embryonic layer that lines the developing gut tube

A

endoderm

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14
Q

what are the airways, lungs and visceral pleura derived from

A

visceral mesoderm and endoderm

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15
Q

what are muscle, CT and cartilage derived from

A

visceral mesoderm

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16
Q

what is internal epithelial lining and glands derived from

17
Q

what is the pleural cavity derived from

18
Q

where is the horizontal fissure of the lungs

A

b/w the cranial lobe and middle lobe

19
Q

where is the oblique fissure of the lungs

A

b/w middle lobe and caudal lobe

20
Q

what is the cardia notch

A

a gap where the cranial and middle lung lobes don’t cover the heart

21
Q

what type of epithelium is found at the mucosa layer and what 3 cell types

A

respiratory epithelium
- ciliated cells
- goblet cells
- basal cells

22
Q

what is the Lamina Propria and where is it found

A

it is a layer of highly vascular loose CT
- has mucous and seromucous glands
**primary site of immune response (lymphocytes+neutrophils)

23
Q

what happens to the epithelium as the tracheobronchial tree branches out

A

it gets shorter and thinner closer to alveoli

lose goblet cells then ciliated cells

24
Q

what do basal cells become

A

basal cells –> club cells –> type II alveolar cells

25
characteristics of the smooth layer of epithelium
- smooth muscle - bronchoconstriction - parasympathetic innervation
26
the mucosa layer is comprised of what two things
epithelium lining lamina propria
27
layer of tissues that is characterized by dense, irregular fibroelastic CT and mucus and seromucous glands
submucosa
28
cartilage layer
hyaline cartilage support adventitia
29
characteristics of club cells
- dome shaped - no cilia - secretory granules provide protection from pollutants + prevent luminal adhesion (collapse)
30
what is the anatomical unit of gas exchange
alveolus
31
site of blood-air barrier
alveolar septum
32
what cells are found in the alveoli and what are their functions
type I alveolar (pneumocyte): gas exchange - makes up 95% of alveolar surface type II alveolar: secrete surfactant and regenerate the epithelium alveolar macrophages